FlyBase is pleased to introduce “Metabolic Pathway reports”, a subset of our Gene Group resource. For example, see the report for GLYCOLYSIS. These manually curated reports aim to facilitate metabolic research in Drosophila by providing high-quality gene lists and visual representations of fly metabolic pathways, integrated with the other rich data in FlyBase.

Metabolic Pathway reports include a curated list of genes that have been experimentally shown or are predicted to act within a pathway. Two visual representations of the pathway are provided: a “text-book” representation (Pathway Thumbnail) manually drawn by FlyBase curators, and a GO-Causal Activity Model (GO-CAM) that is based directly on GO annotation data. Useful links to external resources (FlyCyc, Reactome, KEGG) and publications are provided, as well as options to export the gene list to analysis, download and orthology tools.

You can search for metabolic pathways via the ‘Pathways’ QuickSearch tab or alternatively, browse the ‘Metabolic Pathway reports’ list. For the FB2024_06 release, we provide a first set of 20 pathways involved in carbohydrate metabolism. Additional pathways will be added in the coming year. We welcome any feedback to help improve the usefulness and accuracy of these reports.