A POSTDOCTORAL POSITION is available to study fundamental mechanisms of apoptosis, cell survival and apoptosis-induced compensatory proliferation in Drosophila. Projects involve performing mutagenesis screens, genetic and phenotypic characterization of obtained mutants, and molecular (cloning) and biochemical analyses of the underlying genes. Recent relevant publications about these topics from the lab are listed below. Applicants with a strong background in Drosophila genetics and molecular biology are encouraged to apply.
Send curriculum vitae, a description of research accomplishments and interests, and the names, telephone numbers, and e-mail addresses of three references to:
Dr. Andreas Bergmann, Department of Biochemistry and Molecular Biology University of Texas M. D. Anderson Cancer Center
Website: http://www.mdanderson.org/departments/b ... 508B603A14
Recent relevant publications from the Bergmannlab
Lee TV, Ding T, Chen Z, Rajendran V, Scherr M, Lackey M, Bolduc C, and Bergmann A (2008). The E1-ubiquitin-acitivating-enzyme uba1 in Drosophila controls apoptosis autonomously and tissue growth non-autonomously. Development 135, 43-52.
Wang Y, Werz C, Xu D, Chen Z, Li Y, Hafen E, and Bergmann A (2008). Drosophila cbl is essential for control of cell differentiation and cell death in the developing eye. PLoS ONE 3(1), e1447.
Fan Y and Bergmann A (2008). Distinct Mechanisms of Apoptosis-induced Compensatory Proliferation in Proliferating and Differentiating Eye Tissues in Drosophila. Developmental Cell 14, 399-410.
Fan Y and Bergmann A (2008). Apoptosis-induced Compensatory Proliferation: The cell is dead. Long live the Cell! Trends in Cell Biology 18, 467-473. 2008.
Ditzel M, Broemer M, Tenev T, Bolduc C, Lee TV, Rigbolt KTG, Elliott R, Zvelebil M, Blagoev B, Bergmann A and Meier P (2008). Inactivation of Effector Caspases through non-degradative Polyubiquitylation. Molecular Cell 32, 540-553.
Herz H-M, Woodfield SE, Chen Z, Bolduc C, and Bergmann A (2009). Common and distinct genetic properties of ESCRT-II components in Drosophila. PLoS ONE 4(1): e4165.
Xu D, Woodfield SE, Lee TV, Fan Y, Antonio C, and Bergmann A (2009). Genetic control of programmed cell death (apoptosis) in Drosophila. FLY 3, 78-90.