Aberration Dmel\Df(3L)ri-XT1
| General Information | |||
|---|---|---|---|
| Symbol | Dmel\Df(3L)ri-XT1 | Species | D. melanogaster |
| Name | FlyBase ID | FBab0000008 | |
| Feature type | chromosomal_deletion | Created / Updated | 2006-08-22/2006-08-22 |
| Formalized genetic data | bk1 << knrl << fng << bk2 | ||
| Sequence coordinates | |||
| Deleted segment | 77E2--78A4 | ||
| Duplicated segment | |||
| Computed Breakpoints include | 77E2;[>78A4] | ||
| Breakpoints Inherited | |||
Nature of the Aberration
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| Cytological Order | |||
| Progenitor | |||
| Mutagen | |||
| Class of aberration (relative to progenitor) | |||
| Breakpoints | 77E2-77E4;78A2-78A4 | ||
| Causes alleles | |||
| Carries alleles | |||
| Transposon Insertions | |||
| Genetic mapping information | |||
| Comments | |||
Comments on Cytology
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Left limit of break 1 from polytene analysis (citation unavailable) Right limit of break 1 from inclusion of kni (FBrf0045941) Left limit of break 2 from inclusion of fng (FBrf0076041) The 77E1-4 quadruplet is attenuated, but a distal portion is still present. The 78A5,6 doublet is present, but the 78A1,2 doublet is absent. | |||
Molecularly Mapped Breakpoints
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Sequence Crossreferences
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| DDBJ
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EMBL / GenBank | DNA sequence Protein sequence Name | ||
Gene Deletion & Duplication Data
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Genes Deleted / Disrupted
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| Complementation Data | |||
| Completely deleted / disrupted | |||
| Molecular Data | |||
Genes NOT Deleted / Disrupted
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| Complementation Data | |||
| Molecular Data | |||
Genes Duplicated
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| Complementation Data | |||
| Molecular Data | |||
Genes NOT Duplicated
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| Complementation Data | |||
| Molecular Data | |||
Related Comments
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Phenotypic Data
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| In combination with other aberrations | |||
| NOT in combination with other aberrations | Deletion of abdominal segments, severe head defect and absence of SNS. SNS defect can be rescued by expression of either the knitRa or knrlkni.PR construct. Phenotypic rescue with the knrl transgene is dose dependent, three copies provides an almost normal head as strong as that observed with two copies of kni transgene. Homozygous embryos display abdominal segmentation defect. One copy of Res1r1 lacks the rescued abdominal segments. Mutant abdominal phenotype of Df(3L)ri-XT1 embryos can be rescued by P{kniSH} but only weak rescue of head defects. Mutant embryos have defects in the visceral branch of the tracheal system. Only five tracheal metameres develop, and the tracheal cells do not migrate. When partially rescued with knitRa, segmentation is restored, but dorsal and ventral branches have breaks in the dorsal trunk. Embryos usually lack the visceral branches and if present they are very rudimentary. The Df(3L)ri-XT1 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3\'WP-2,wvar}2Lt insertion). Tracheal metameres in remaining 5 abdominal segments of homozygotes show much more disrupted phenotype than kni8. Rudimentary tracheal metameres invaginate but lack primary branching and interconnections. When combined with knitRa, dorsal trunk formation is similar to wild type, though dorsal outgrowth fails and lateral trunk fusion is only partial. Visceral and ganglionic tracheal branches fail to reach the gut and nervous system. Lack of tracheal branch formation is caused by failure of cell migration. | ||
Position Effect Variegation Data
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Stocks
( 2 ) | |||
| Kyoto | |||
| Bloomington | |||
Notes on Origin
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| Discoverer | |||
Balancer / Genotype Variants of the Aberration
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Separable Components
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Other Comments
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Synonyms & Secondary IDs
( 9 ) | |||
| Reported As | |||
| Symbol Synonym | Df(3L)ri-XT1 Df(3L)riXT1 Df(3L)rixTi Df(3L)riXT1 Df(3L)ri-XT1 Df(3L)XT1 DfriXT1 fngDf XT1 | ||
| Name Synonym | |||
| Secondary FlyBase IDs | |||
References
( 23 ) | |||
| Generate a list of | |||
| List References by type |
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Recent research papers ( 1 ) | |||
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Recent reviews (0)
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| All reviews listed in FlyBase were published before 2006 | |||
Nature of the Aberration