A Database of Drosophila Genes & Genomes

 

Aberration Dmel\Df(3R)awd-KRB

General Information
SymbolDmel\Df(3R)awd-KRBSpeciesD. melanogaster
NameFlyBase IDFBab0000009
Feature typechromosomal_deletionCreated / Updated2006-08-22/2006-08-22
Formalized genetic data Med << bk1 << l(3)100CDa << bk2
Sequence coordinates
Deleted segment100D1--100D4
Duplicated segment
Computed Breakpoints include 100D1;100D3-100D4
Breakpoints Inherited  
hide Nature of the Aberration
Cytological Order
Progenitor
Mutagen
Class of aberration (relative to progenitor)
chromosomal_deletion
(Roseman et al., 1995, Raftery, 1995.4.6, Harbecke and Lengyel, 1995, Giesen et al., 1997, Salzberg et al., 1997, Duffy et al., 1996, Wisotzkey et al., 1998)
Breakpoints
100C;100D
(Harbecke and Lengyel, 1995, Roseman et al., 1995, Duffy et al., 1996, Giesen et al., 1997, Salzberg et al., 1997)
100C6-100D1;100D1-100D4
(Raftery, 1995.4.6)
100C6-100C7;100D3-100D4
(Wisotzkey et al., 1998)
Causes alleles
Carries alleles
Transposon Insertions
Genetic mapping information
Comments
Breakpoint(s) molecularly mapped
(Xiong and Montell, 1993)
hide Comments on Cytology
Left limit of break 1 from non-inclusion of Med (FBrf0086254) Right limit of break 1 from polytene analysis (FBrf0086254) Left limit of break 2 from polytene analysis (FBrf0102610) Right limit of break 2 from polytene analysis (FBrf0086254)
 
Ref: FBrf0048096.
(Salzberg et al., 1997)
hide Molecularly Mapped Breakpoints
 
hide Sequence Crossreferences
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
hide Gene Deletion & Duplication Data
hide Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
ttk
(Xiong and Montell, 1993, BDGP Project Members, 1994-1999, Salzberg et al., 1994, Giesen et al., 1997, Szeged Stock Center, 1998-, Spradling et al., 1999, French et al., 2003, Cook, 2006.1.31)
awd
(Cook, 2006.1.31)
l(3)100CDa
(Roseman et al., 1995)
l(3)S139101
(Szeged Stock Center, 1998-)
l(3)S058209b
(Szeged Stock Center, 1998-)
l(3)S008224
(Szeged Stock Center, 1998-)
Molecular Data
hide Genes NOT Deleted / Disrupted
Complementation Data
Aly
(BDGP Project Members, 1994-1999, Spradling et al., 1999)
dco
(Cook, 2006.1.31)
γCop
(Salzberg et al., 1997)
pygo
(Cook, 2006.1.31)
heph
(Cook, 2006.1.31)
Med
(Raftery, 1995.4.6, Wisotzkey et al., 1998, Cook, 2006.1.31)
l(3)rM731
(BDGP Project Members, 1994-1999, Spradling et al., 1999, Cook, 2006.1.31)
l(3)S125015b
(Szeged Stock Center, 1998-)
Molecular Data
hide Genes Duplicated
Complementation Data
Molecular Data
hide Genes NOT Duplicated
Complementation Data
Molecular Data
hide Related Comments
hide Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations
Df(3R)awd-KRB homozygous embryos exhibit major disruption of the tracheal network accompanied by ectopic branching and looping, appearance of a few extra branches or "knobs", and migration abnormalities.
(Dammai et al., 2003)
Deficient embryos show an uninterpretable mutant midgut phenotype.
(Bilder and Scott, 1995)
Does not give a Minute phenotype when heterozygous.
(Cook, 2006.1.31)
Dominantly causes tergite defects in less than 50% of run3 heterozygotes.
(Duffy et al., 1996)
Has a partially penetrant dominant cuticle phenotype.
(Cox et al., 2000)
Heterozygous embryos sometimes have gaps (consisting of patches of naked cuticle) in the denticle belts.
(Desbordes et al., 2005)
Homozygous embryos are very abnormal compared to wild-type.
(Harbecke and Lengyel, 1995)
No second site non-complementing phenotype with zipEbr and zipmhc-c6.1.
(Halsell and Kiehart, 1998)
Shows dominant enhancement of dominant haltere phenotype caused by Ubx195 and Ubx9.22.
(Burnette et al., 1999)
Shows no maternal enhancement of dpphr4.
(Nicholls and Gelbart, 1998)
The Df(3R)awd-KRB chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3\'WP-2,wvar}2Lt insertion).
(Mason et al., 2004)
hide Position Effect Variegation Data
  
hide Stocks ( 2 )
Bloomington
3369
y*; Df(3R)awd-KRB, e* ca1/TM3, Sb1 Ser1
Kyoto
107013
y*; Df(3R)awd-KRB, e* ca1/TM3, Sb1 Ser1
hide Notes on Origin
Discoverer
hide Balancer / Genotype Variants of the Aberration
    hide Separable Components
      hide Other Comments
      hide Synonyms & Secondary IDs ( 5 )
      Reported As
      Symbol Synonym
      Df(3R)awd
      (Duffy et al., 1996, Harbecke and Lengyel, 1995)
      Df(3R)awdKRB
      (Brumby et al., 2004, Dammai et al., 2003, Giesen et al., 1997, Weber et al., 1995, Xiong and Montell, 1993, Salzberg et al., 1994)
      Df(3R)awdkrb
      (LaJeunesse et al., 2001)
      Df(3R)awd-KRB
      (Wilson et al., 2006)
      Df(3R)KRB
      (Raftery, 1995.4.6)
      Name Synonym
      Secondary FlyBase IDs
        hide References ( 35 )
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        hide Recent research papers ( 1 )
        Wilson et al., 2006, Genetics 173(3): 1455--1463
        High-resolution mapping of quantitative trait loci affecting increased life span in Drosophila melanogaster. [FBrf0194188]
        Show all research papers ...