Aberration Dmel\Df(3L)81k19

General Information
Symbol	Dmel\Df(3L)81k19	Species	D. melanogaster
Name		FlyBase ID	FBab0000011
Feature type	chromosomal_deletion
Also Known As	Df(3L)st-81k19

Computed Breakpoints include	73A3;74F1-74F4
Deleted segment	73A3--74F4
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Aberration
Cytological Order
Progenitor
Mutagen
Class of aberration (relative to progenitor)	chromosomal_deletion (James and Collier, 1992, Pauli et al., 1995, Fletcher and Thummel, 1995, Urness and Thummel, 1995, Harbecke and Lengyel, 1995, Cunniff et al., 1997, Deak et al., 1997, Biyasheva et al., 2001)
Breakpoints	73A3;74A (Deak et al., 1997) 73A3;74F (James and Collier, 1992, Pauli et al., 1995, Harbecke and Lengyel, 1995, Fletcher and Thummel, 1995, Urness and Thummel, 1995, Cunniff et al., 1997)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	bk1 << SS3-5 << Eip74EF << bk2 << Eip75B
Genetic mapping information
Comments
Comments on Cytology
	Ref: FBrf0100929. (Urness and Thummel, 1995) Left limit of break 1 from polytene analysis (FBrf0055827) Right limit of break 1 from inclusion of argos (FBrf0067338) Left limit of break 2 from inclusion of Eip74EF (FBrf0055827) Right limit of break 2 from polytene analysis (FBrf0055827)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	Abl (Spradling et al., 1999) aos (Gaengel and Mlodzik, 2003, BDGP Project Members, 1994-1999, Wemmer and Klambt, 1995) Baldspot (Spradling et al., 1999, BDGP Project Members, 1994-1999) blot (Johnson et al., 1999) Eip74EF (Halsell and Kiehart, 1998, Spradling et al., 1999, Lee and Baehrecke, 2001, James and Collier, 1992, BDGP Project Members, 1994-1999, Russell et al., 1996) etiolated (Ghabrial et al., 2011) frc (Szeged Stock Center, 1998-, Spradling et al., 1999, Selva et al., 2001, Goto et al., 2001, BDGP Project Members, 1994-1999, Deak et al., 1997) Int6 (Spradling et al., 1999, BDGP Project Members, 1994-1999, Cunniff et al., 1997) Krn (Schupbach, 2000.3.3) l(3)02634 (BDGP Project Members, 1994-1999) l(3)04069b (Spradling et al., 1999, BDGP Project Members, 1994-1999) l(3)06266 (BDGP Project Members, 1994-1999) l(3)j11B2 (Spradling et al., 1999, BDGP Project Members, 1994-1999) l(3)S001405 (Szeged Stock Center, 1998-) l(3)s1629b (Spradling et al., 1999, BDGP Project Members, 1994-1999) l(3)S001925 (Szeged Stock Center, 1998-) l(3)S005029a (Deak et al., 1997) l(3)S011524 (Deak et al., 1997) l(3)S014708 (Deak et al., 1997) l(3)S022564 (Szeged Stock Center, 1998-) l(3)S023204a (Deak et al., 1997) l(3)S023549 (Szeged Stock Center, 1998-) l(3)S027005 (Deak et al., 1997) l(3)S038305 (Deak et al., 1997) l(3)S042420 (Szeged Stock Center, 1998-) l(3)S049701 (Deak et al., 1997) l(3)S063319 (Deak et al., 1997) l(3)S073615 (Szeged Stock Center, 1998-, Deak et al., 1997) l(3)S075901 (Deak et al., 1997) l(3)S096611 (Szeged Stock Center, 1998-) l(3)S103114 (Szeged Stock Center, 1998-) l(3)S103909 (Szeged Stock Center, 1998-) l(3)S123208 (Szeged Stock Center, 1998-) l(3)S145710a (Szeged Stock Center, 1998-, Deak et al., 1997) l(3)S147114 (Deak et al., 1997) Mo25 (Spradling et al., 1999, BDGP Project Members, 1994-1999) S(CycE^JP)3.1 (Brumby et al., 2004) SS3-5 (Neufeld et al., 1998) tap (Ledent et al., 1998, BDGP Project Members, 1994-1999)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	cp (Kennison, 2006.7.21) Eip75B (Spradling et al., 1999, BDGP Project Members, 1994-1999) l(3)neo20 (Spradling et al., 1999, BDGP Project Members, 1994-1999) l(3)S103505b (Szeged Stock Center, 1998-) ms(3)73D (BDGP Project Members, 1994-1999) Wow (Birchler et al., 1994)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	The Df(3L)81k19 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion). (Mason et al., 2004) Causes inviability or low viability in hybrid females when heterozygous with D.simulans chromosome. (Coyne et al., 1998) Strong second site non-complementing phenotype with zip^Ebr and zip^mhc-c6.1: malformed phenotype penetrance >75%. (Halsell and Kiehart, 1998) Shows no maternal enhancement of dpp^hr4. (Nicholls and Gelbart, 1998) P{hs-Eip78C-B} expression in heterozygotes causes a reduction in the 63E, 71CD and 82F late puffs and the 62E early/late puff. (Russell et al., 1996) Midgut development of mutant embryos is wild type. (Bilder and Scott, 1995) Homozygous embryos show abnormal head involution, germband retraction and dorsal closure. Midgut constrictions do not form and Malpighian tubules are not completely elongated. (Harbecke and Lengyel, 1995) Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovo^D2. (Pauli et al., 1995)
Stocks ( 2 )
Bloomington	2998 Df(3L)81k19/TM6B, Tb¹
Kyoto	107518 Df(3L)81k19/TM6B, Tb¹
Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 12 )
Reported As
Symbol Synonym	81K19 (Yamaguchi et al., 2001) Df(3)81k19 (Selva et al., 2001) Df(3)83K19 (Ledent et al., 1998) Df(3L)81^k19 (Kraft et al., 2006) Df(3L)81K19 (Brumby et al., 2004, Goto et al., 2001, Shamloula et al., 2002, Lee et al., 2001, Firth et al., 2000, Johnson et al., 1999, Nicholls and Gelbart, 1998, Deak et al., 1997, Harbecke and Lengyel, 1995, Bilder and Scott, 1995, Pauli et al., 1995, Martin et al., 2005) Df(3L)81k19 (Pepple et al., 2007, Kennison, 2006.7.21, Curtis et al., 2011, He et al., 2005, Ihry et al., 2012, Munoz-Soriano et al., 2012, Ghabrial et al., 2011) Df(3L) 81K19 (Fiehler and Wolff, 2008) Df(3L)st-81k19 (Martin and Baehrecke, 2004, Lee and Baehrecke, 2001, Jiang et al., 2000, Urness and Thummel, 1995, Fletcher and Thummel, 1995, Fletcher et al., 1995) Df(3L)st-81k-19 (Lee et al., 2002) Df(3L)st81k19 (Biyasheva et al., 2001) Df(3L)st 81k19 (Cunniff et al., 1997) Df^3Lst-8IK19 (Daish et al., 2003)
Name Synonym
Secondary FlyBase IDs

References ( 64 )

Generate a list of	All references relating to this aberration ( 64 )

List References by type	Research paper ( 57 ) Personal communication to FlyBase ( 4 ) Abstract ( 1 ) FlyBase analysis ( 1 ) Stock list ( 1 )
Recent research papers ( 4 )
	Ihry et al., 2012, PLoS Genet. 8(11): e1003085 Translational Control by the DEAD Box RNA Helicase belle Regulates Ecdysone-Triggered Transcriptional Cascades. [FBrf0220149] Munoz-Soriano et al., 2012, J. Mol. Neurosci. 48(1): 136--143 Septin 4, the Drosophila Ortholog of Human CDCrel-1, Accumulates in parkin Mutant Brains and is Functionally Related to the Nedd4 E3 Ubiquitin Ligase. [FBrf0219099] Curtis et al., 2011, Dev. Biol. 350(2): 534--547 Histone lysine demethylases function as co-repressors of SWI/SNF remodeling activities during Drosophila wing development. [FBrf0212876] Ghabrial et al., 2011, PLoS Genet. 7(7): e1002087 A systematic screen for tube morphogenesis and branching genes in the Drosophila tracheal system. [FBrf0214368] Show all research papers ...