Aberration Dmel\C(1)DX

General Information
Symbol	Dmel\C(1)DX	Species	D. melanogaster
Name	Compound (1) Double X	FlyBase ID	FBab0000080
Feature type	homo_compound_chromosome

Computed Breakpoints include
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor	In(1)dl-49 In(1)sc⁸
Mutagen	X ray
Class of aberration (relative to progenitor)
Breakpoints
Causes alleles
Carries alleles	f¹ (The Moscow Regional Drosophila melanogaster Stock Center, Dubna) y¹ (The Moscow Regional Drosophila melanogaster Stock Center, Dubna)
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments
Comments on Cytology
	C(1)DX, In(1)dl-49 - In(1)sc⁸., y f - y^- sc⁸ f..
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	bb
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations	Oocytes from All-Compound females produce anaphase I and meiosis II figures 64% of the time, i.e. they have bypassed metaphase I arrest. (Jang et al., 1995)
NOT in combination with other aberrations	A reversed acrocentric heterozygous for In(1)dl-49; it is useful in balancing because it is very stable, which is probably due to little interstitial heterochromatin. y w f detachments very rarely produced. Also produces a low incidence of homozygosis for w. C(1)DX/0 lethal
Stocks ( 568 )
Bloomington	784 FM6/C(1)DX, y^* f¹ 1303 FM7k/C(1)DX, y¹ f¹ 5263 FM7i/C(1)DX, y¹ f¹ 5265 FM7d/C(1)DX, y¹ f¹ 4428 FM7b/Y & C(1)DX, y¹ f¹/Y 83 r⁹/C(1)DX, y¹ f¹
Kyoto	106077 FM6/C(1)DX, y^* f¹ 106271 FM7k/C(1)DX, y¹ f¹ 108132 FM7i/C(1)DX, y¹ f¹ 108134 FM7d/C(1)DX, y¹ f¹ 107738 FM7b/Y & C(1)DX, y¹ f¹/Y 105722 r⁹/C(1)DX, y¹ f¹
	More stocks available...
Notes on Origin
Discoverer	Muller.
	Induced on: In(1)dl-49 y¹ w¹ f¹/In(1)sc⁸ sc⁸ B¹.
Balancer / Genotype Variants of the Aberration
	C(1)DX-P
Separable Components

Other Comments
	Some versions also marked with w¹. (The Moscow Regional Drosophila melanogaster Stock Center, Dubna) A study of metaphase arrest found that crossovers between homologs attached to the same centromere do not induce metaphase arrest. Hence exchanges induce metaphase arrest only when they physically conjoin two separate kinetochores. The signal that mediates metaphase arrest is not the exchange event per se, but the resulting tension on homologous kinetochores. (Jang et al., 1995) Attached X chromosomes homozygous for various w alleles were used to study dosage compensation of w. (Birchler, 1992) female <up>stated by Muller to have been In(1)dl-49/In(1)sc^8Ly^3PR, but the derivative does not carry y^3P</up>. Was originally y¹ w¹ f¹ - y^- sc⁸ B¹ ., but by double exchange f¹ became homozygous and B¹ was lost. y¹, w¹, f¹ versions exist.
Synonyms & Secondary IDs ( 6 )
Reported As
Symbol Synonym	:= C(1)DX (Rakovitsky et al., 2007, Sokac and Wieschaus, 2008) C(1) DX (De Renzis et al., 2006) nulloX (Sokac and Wieschaus, 2008)
Name Synonym	Compound-1 DX (Skaer and Simpson, 2000) Compound (1) Double X
Secondary FlyBase IDs

References ( 23 )

Generate a list of	All references relating to this aberration ( 23 )

List References by type	Research paper ( 20 ) Stock list ( 2 ) Book ( 1 )
Recent research papers (0)
	All research papers listed in FlyBase were published before 2011 Show research papers ...