A Database of Drosophila Genes & Genomes

 

Aberration Dmel\C(1)DX

General Information
SymbolDmel\C(1)DXSpeciesD. melanogaster
NameCompound (1) Double XFlyBase IDFBab0000080
Feature typehomo_compound_chromosomeCreated / Updated2006-08-22/2006-08-22
Formalized genetic data
Sequence coordinates
Deleted segment
Duplicated segment
Computed Breakpoints include
Breakpoints Inherited  
hide Nature of the Aberration
Cytological Order
Progenitor
In(1)dl-49
 
In(1)sc8
 
Mutagen
X ray
 
Class of aberration (relative to progenitor)
Breakpoints
Causes alleles
Carries alleles
f1
(The Moscow Regional Drosophila melanogaster Stock Center, Dubna)
y1
(The Moscow Regional Drosophila melanogaster Stock Center, Dubna)
Transposon Insertions
Genetic mapping information
Comments
hide Comments on Cytology
C(1)DX, In(1)dl-49 - In(1)sc8., y f - y- sc8 f..
 
hide Molecularly Mapped Breakpoints
 
hide Sequence Crossreferences
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
hide Gene Deletion & Duplication Data
hide Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
bb
 
Molecular Data
hide Genes NOT Deleted / Disrupted
Complementation Data
Molecular Data
hide Genes Duplicated
Complementation Data
Molecular Data
hide Genes NOT Duplicated
Complementation Data
Molecular Data
hide Related Comments
hide Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations
A reversed acrocentric heterozygous for In(1)dl-49; it is useful in balancing because it is very stable, which is probably due to little interstitial heterochromatin. y w f detachments very rarely produced. Also produces a low incidence of homozygosis for w. C(1)DX/0 lethal
 
hide Position Effect Variegation Data
  
hide Stocks ( 577 )
Bloomington
784
FM6/C(1)DX, y* f1
1303
FM7k/C(1)DX, y1 f1
5263
FM7i/C(1)DX, y1 f1
5265
FM7d/C(1)DX, y1 f1
773
In(1)AB/C(1)DX, y1 f1
4333
T(1;4)4C3/C(1)DX, y1 f1
4428
FM7b/Y & C(1)DX, y1 f1/Y
Kyoto
106077
FM6/C(1)DX, y* f1
106271
FM7k/C(1)DX, y1 f1
108132
FM7i/C(1)DX, y1 f1
108134
FM7d/C(1)DX, y1 f1
107738
FM7b/Y & C(1)DX, y1 f1/Y
hide Notes on Origin
Discoverer
Muller.
 
Induced on: In(1)dl-49 y1 w1 f1/In(1)sc8 sc8 B1.
 
hide Balancer / Genotype Variants of the Aberration
hide Separable Components
    hide Other Comments
    female [stated by Muller to have been In(1)dl-49/In(1)sc8Ly3PR, but the derivative does not carry y3P]. Was originally y1 w1 f1 - y- sc8 B1 ., but by double exchange f1 became homozygous and B1 was lost. y1, w1, f1 versions exist.
     
    Attached X chromosomes homozygous for various w alleles were used to study dosage compensation of w.
    (Birchler, 1992)
    A study of metaphase arrest found that crossovers between homologs attached to the same centromere do not induce metaphase arrest. Hence exchanges induce metaphase arrest only when they physically conjoin two separate kinetochores. The signal that mediates metaphase arrest is not the exchange event per se, but the resulting tension on homologous kinetochores.
    (Jang et al., 1995)
    Some versions also marked with w1.
    (The Moscow Regional Drosophila melanogaster Stock Center, Dubna)
    hide Synonyms & Secondary IDs ( 4 )
    Reported As
    Symbol Synonym
    :=
     
    C(1)DX
     
    Name Synonym
    Compound-1 DX
    (Skaer and Simpson, 2000)
    Compound (1) Double X
     
    Secondary FlyBase IDs
      hide References ( 20 )
      Research paper
      Niemi et al., 2004, Genetics 166(1): 255--264
      Establishment and maintenance of the P cytotype associated with telomeric P elements in Drosophila melanogaster. [FBrf0174706]
      Schumacher et al., 2004, Development 131(11): 2631--2640
      The RhoGEF Pebble is required for cell shape changes during cell migration triggered by the Drosophila FGF receptor Heartless. [FBrf0179437]
      Simmons et al., 2004, Genetics 166(1): 243--254
      The P cytotype in Drosophila melanogaster: a maternally transmitted regulatory state of the germ line associated with telomeric P elements. [FBrf0174705]
      Webber et al., 2004, J. Cell Biol. 164(6): 819--829
      The cohesion protein ORD is required for homologue bias during meiotic recombination. [FBrf0174802]
      Hunter et al., 2002, Molec. Biol. Cell 13(1): 146--157
      Conserved domains of the nullo protein required for cell-surface localization and formation of adherens junctions. [FBrf0145107]
      de Carvalho et al., 2001, Proc. Natl. Acad. Sci. USA 98(23): 13225--13230
      Identification of five new genes on the Y chromosome of Drosophila melanogaster. [FBrf0141717]
      Green and Piergentili, 2000, Proc. Natl. Acad. Sci. USA 97(26): 14484--14487
      On the origin of metacentric, attached-X (A-X) chromosomes in Drosophila melanogaster males. [FBrf0132437]
      Skaer and Simpson, 2000, Dev. Biol. 221(1): 148--167
      Genetic analysis of bristle loss in hybrids between Drosophila melanogaster and D. simulans provides evidence for divergence of cis-regulatory sequences in the achaete-scute gene complex. [FBrf0127332]
      Zakharenko et al., 2000, Molec. gen. Genet. 263(2): 335--341
      hobo-induced rearrangements are responsible for mutation bursts at the yellow locus in a natural population of Drosophila melanogaster. [FBrf0127410]
      Helms et al., 1999, Dev. Biol. 215(2): 358--374
      Engineered truncations in the Drosophila mastermind protein disrupt Notch pathway function. [FBrf0111904]
      Mason et al., 1997, Genetics 146(4): 1381--1397
      Germ-line effects of a mutator, mu2, in Drosophila melanogaster. [FBrf0095657]
      Jang et al., 1995, Science 268(5219): 1917--1919
      Induction of metaphase arrest in Drosophila oocytes by chiasma-based kinetochore tension. [FBrf0082182]
      Birchler, 1992, Genet. Res. 59(1): 11--18
      Expression of cis-regulatory mutations of the white locus in metafemales of Drosophila melanogaster. [FBrf0056147]
      Prudhommeau and Proust, 1990, Mutat. Res. 230: 135--157
      I-R hybrid dysgenesis in Drosophila melanogaster: nature and site specificity of induced recessive lethals. [FBrf0052612]
      Zhimulev et al., 1987, Biol. Zentbl. 106(6): 699--720
      Fine cytogenetical analysis of the band 10A1-2 and the adjoining regions in the Drosophila melanogaster X-chromosome. [FBrf0045718]
      Valencia et al., 1949, D. I. S. 23: 99--102
      Formation of attached X's by reverse crossing over in the heterochromatic region. [FBrf0007401]
      Muller, 1943, D. I. S. 17: 61--62
      A stable double X chromosome. [FBrf0005925]
      Stock list
      The Moscow Regional Drosophila melanogaster Stock Center, Dubna, Russia, 1997, D. I. S. 80: 109--130
      Stock list. [FBrf0098381]
      Bloomington Drosophila Stock Center, 19??-, Bloomington Stock List.
      Bloomington Stock List. [FBrf0141259]
      Book
      Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster.
      The Genome of Drosophila melanogaster. [FBrf0066905]