A Database of Drosophila Genes & Genomes

 

Aberration Dmel\C(1)M4

General Information
SymbolDmel\C(1)M4SpeciesD. melanogaster
NameFlyBase IDFBab0000083
Feature typehomo_compound_chromosomeCreated / Updated2006-08-22/2006-08-22
Formalized genetic data
Sequence coordinates
Deleted segment
Duplicated segment
Computed Breakpoints include
Breakpoints Inherited  
hide Nature of the Aberration
Cytological Order
Progenitor
In(1)FM7
 
In(1)wm4
 
In(1)AB
 
Mutagen
X ray
 
Class of aberration (relative to progenitor)
Breakpoints
Causes alleles
Carries alleles
Transposon Insertions
Genetic mapping information
Comments
hide Comments on Cytology
C(1)M4, In(1)wm4 + AB - FM7., y wm4 - y- wa vOf sc8..
 
hide Molecularly Mapped Breakpoints
 
hide Sequence Crossreferences
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
hide Gene Deletion & Duplication Data
hide Genes Deleted / Disrupted
Complementation Data
Molecular Data
hide Genes NOT Deleted / Disrupted
Complementation Data
Molecular Data
hide Genes Duplicated
Complementation Data
Molecular Data
hide Genes NOT Duplicated
Complementation Data
Molecular Data
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hide Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations
Because of the In(1)wm4/wa constitution, C(1)M4 females without a Y chromosome display strong variegation, those with YS moderate variegation and those with YL or a complete Y almost no variegation. A powerful enhancer of autosomal recombination, but has low viability in combination with autosomal rearrangements.
 
hide Position Effect Variegation Data
Genes subject to PEV
w
 
hide Stocks ( 39 )
Bloomington
988
FM7a/Y/C(1)M4
12555
w1118 P{GT1}BG01022/C(1)M4
4738
In(1)AB, f1/C(1)M4, y2
1999
C(1)M4, y2/C(1;Y)6, w1118
1177
C(1)M4, y2/shi1; In(3LR)234
2000
C(1)M4, y2/Y & C(1;Y)6, w1118/Y
8867
Zhr7F/C(1)M4, y2/Dp(1;Y)y+
1204
C(1)M4, y2; In(3L)P, rs2 th1
1175
C(1)M4, y2/shi1; In(3LR)C190/Sb1
3073
C(1)M4, y2; In(3LR)A114/Sb1 Ubx1
Kyoto
106158
FM7a/Y/C(1)M4
101126
In(1)AB, fM1 / C(1)M4, y2
hide Notes on Origin
Discoverer
Craymer, May 1972.
 
Induced on: In(1)wm4 In(1)AB.
 
exchange of the proximal heterochromatin of In(1)wm4 + AB and the distal heterochromatin of FM7
 
hide Balancer / Genotype Variants of the Aberration
    hide Separable Components
      hide Other Comments
      Detachment rate approximately 1/15,000. Useful in maintenance of XY-bearing stocks without a free Y. Some derivatives are marked with y2 bb-.
       
      hide Synonyms & Secondary IDs ( 1 )
      Reported As
      Symbol Synonym
      C(1)M4
       
      Name Synonym
      Secondary FlyBase IDs
        hide References ( 5 )
        Research paper
        Schotta et al., 2002, EMBO J. 21(5): 1121--1131
        Central role of Drosophila SU(VAR)3-9 in histone H3-K9 methylation and heterochromatic gene silencing. [FBrf0144851]
        Sawamura et al., 2000, Proc. Natl. Acad. Sci. USA 97(6): 2652--2655
        Genetic analysis of speciation by means of introgression into Drosophila melanogaster. [FBrf0127307]
        Craymer, 1974, D. I. S. 51: 21
        [New mutants report.] [FBrf0026093]
        Review
        Presgraves et al., 2003, Nature 423: 715--718
        Adaptive evolution drives divergence of a hybrid inviability gene between two species of Drosophila. [FBrf0159638]
        Book
        Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster.
        The Genome of Drosophila melanogaster. [FBrf0066905]