Aberration Dmel\Df(1)C149

General Information
Symbol	Dmel\Df(1)C149	Species	D. melanogaster
Name		FlyBase ID	FBab0000350
Feature type	chromosomal_deletion	Created / Updated	2006-08-22/2006-08-22

Formalized genetic data	fs(1)A456 << bk1 << pbr << bk2 << rux
Sequence coordinates
Deleted segment	5A8--5C5
Duplicated segment
Computed Breakpoints include	5A8-5A9;5C5
Breakpoints Inherited
Nature of the Aberration
Cytological Order
Progenitor
Mutagen	X ray
Class of aberration (relative to progenitor)	chromosomal_deletion (Oliver et al., 1988, Deak et al., 1982, Pauli et al., 1995, Duffy et al., 1996, Savvateeva et al., 1985, Cook et al., 1997, Harbecke and Lengyel, 1995, Anand and Chandra, 1994, Craymer and Roy, 1980)
Breakpoints	5A8-5A9;5C5-5C6 (Craymer and Roy, 1980, Deak et al., 1982, Savvateeva et al., 1985, Anand and Chandra, 1994, Pauli et al., 1995, Harbecke and Lengyel, 1995, Duffy et al., 1996, Cook et al., 1997) 5A8-5A9;5C5 (Oliver et al., 1988)
Causes alleles
Carries alleles
Transposon Insertions
Genetic mapping information
Comments
Comments on Cytology
	Limits of break 1 from polytene analysis (FBrf0034402) Left limit of break 2 from polytene analysis (FBrf0034402) Right limit of break 2 from polytene analysis (FBrf0048195)
Molecularly Mapped Breakpoints

Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	cv (Craymer and Roy, 1980, Oliver et al., 1988) fs(1)M3 (Komitopoulou et al., 1983) Act5C (Sodja et al., 1982) mus105 (Baker and Smith, 1979) pbr (Giorgi et al., 1993)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	brn (Oliver et al., 1988) mei-9 (Oliver et al., 1988) bi (Oliver et al., 1988) rb (Oliver et al., 1988) snf (Oliver et al., 1988) rux (Craymer and Roy, 1980) fs(1)M3 (Degelmann et al., 1990) peb (Oliver et al., 1988) norpA (Oliver et al., 1988) ec (Oliver et al., 1988) ovo (Oliver et al., 1988) lac (Oliver et al., 1988) cho (Oliver et al., 1988) fs(1)A1059 (Oliver et al., 1988) l(1)5CDa (Savvateeva et al., 1985) fs(1)A456 (Oliver et al., 1988) qed (Florence, 1999.7.22) amb (Oliver et al., 1988) kdn (Fergestad et al., 2006) rg (Oliver et al., 1988)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	Does not cause unconditional lethality in hybrid females when heterozygous with D.simulans chromosome. (Coyne et al., 1998) Dominantly causes tergite defects in less than 50% of run³ heterozygotes. (Duffy et al., 1996) Hemizygous embryos were examined with polarised light microscopy and antibody staining and found to have wild type muscle pattern and contraction. (Drysdale et al., 1993) Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovo^D2. (Pauli et al., 1995) Midgut development of mutant embryos is wild type. (Bilder and Scott, 1995) No second site non-complementing phenotype with zip^Ebr and zip^mhc-c6.1. (Halsell and Kiehart, 1998) No significant change in female lethality when in combination with Sxl^f1. (Anand and Chandra, 1994) Shows no maternal enhancement of dpp^hr4. (Nicholls and Gelbart, 1998) Transmission rate of Dp(1;f)J21A through females to progeny is 28%, Df(1)C149 has no effect on transmission. (Cook et al., 1997)
Position Effect Variegation Data

Stocks ( 2 )
Bloomington	945 Df(1)C149/FM6
Kyoto	108925 Df(1)C149/FM6
Notes on Origin
Discoverer	Lefevre.

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	C149 (Sanchez et al., 1994) Df(1)C149 (Fergestad et al., 2006, Crest et al., 2007)
Name Synonym
Secondary FlyBase IDs

References ( 38 )

Generate a list of	All references relating to this aberration ( 38 )

List References by type	Research paper ( 35 ) Personal communication to FlyBase ( 1 ) FlyBase analysis ( 1 ) Book ( 1 )
Recent research papers ( 2 )
	Crest et al., 2007, Genetics 175(2): 567--584 Onset of the DNA replication checkpoint in the early Drosophila embryo. [FBrf0194644] Fergestad et al., 2006, Genetics 173(3): 1357--1364 Metabolic disruption in Drosophila bang-sensitive seizure mutants. [FBrf0194355] Show all research papers ...