Aberration Dmel\Df(1)C246

General Information
Symbol	Dmel\Df(1)C246	Species	D. melanogaster
Name		FlyBase ID	FBab0000355
Feature type	chromosomal_deletion
Also Known As	C246

Computed Breakpoints include	11D1;12A1
Deleted segment	11D1--12A1
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor
Mutagen	X ray
Class of aberration (relative to progenitor)	chromosomal_deletion (Deak et al., 1982, Pauli et al., 1995, Mason et al., 1981, Kulkarni et al., 1988, Duffy et al., 1996, Harbecke and Lengyel, 1995, Craymer and Roy, 1980)
Breakpoints	11;12A1-12A2 (Deak et al., 1982) 11D-11E;12A1 (Duffy et al., 1996) 11D-11E;12A1-12A2 (Kulkarni et al., 1988, Pauli et al., 1995, Harbecke and Lengyel, 1995) 11D;12A1-12A2 (Craymer and Roy, 1980, Mason et al., 1981) [];12A1--2 (Fyrberg et al., 1990)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	gs(1)N41 << bk1 << l(1)11Dc << Gpt << bk2 << up
Genetic mapping information
Comments
Comments on Cytology
	Left limit of break 1 from polytene analysis (citation unavailable) Right limit of break 1 from inclusion of rad (FBrf0053305) Left limit of break 2 from polytene analysis (FBrf0034402) Right limit of break 2 from polytene analysis (FBrf0086390)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	Bap60 (Brumby et al., 2002) comt (Sanyal and Krishnan, 2001) rad (Folkers et al., 1991, Folkers et al., 1993) s (Craymer and Roy, 1980, Deak et al., 1982) sno (Coyle-Thompson and Banerjee, 1993) wy (Craymer and Roy, 1980, Deak et al., 1982)
Molecular Data
Completely deleted	Rbp1-like (Kumar and Lopez, 2005)
Genes NOT Deleted / Disrupted
Complementation Data
	gs(1)N41 (Hatanaka and Okada, 1991) mei-41 (Mason et al., 1981) mh (Loppin et al., 2001) mus101 (Mason et al., 1981) mus106 (Laurencon, 2001.7.23) mus109 (Mason et al., 1981) nonA (Kulkarni et al., 1988) sesB (Rikhy et al., 2003) up (Deak et al., 1982, Homyk and Emerson, 1988)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations	YSX.YL, Df(1)C246, In(1)EN, y M/C(1;Y)2, Df(1)g^l In(1)EN, y g f B females are viable, yellow and Minute (Schalet).
NOT in combination with other aberrations	Shows dominant enhancement of dominant haltere phenotype caused by Ubx¹⁹⁵ and Ubx^9.22. (Burnette et al., 1999) Does not cause unconditional lethality in hybrid females when heterozygous with D.simulans chromosome. (Coyne et al., 1998) No second site non-complementing phenotype with zip^Ebr and zip^mhc-c6.1. (Halsell and Kiehart, 1998) Shows no maternal enhancement of dpp^hr4. (Nicholls and Gelbart, 1998) Dominantly causes tergite defects in less than 50% of run³ heterozygotes. (Duffy et al., 1996) Deficient embryos show an uninterpretable mutant midgut phenotype. (Bilder and Scott, 1995) Heterozygosity for this deletion suppresses the mutant ovarian phenotype of ovo^D2. (Pauli et al., 1995) Hemizygous embryos were examined with polarised light microscopy and antibody staining: muscle pattern incomplete due to muscle absences and detachments. (Drysdale et al., 1993) Mutants show a moderate Minute phenotype. (Craymer and Roy, 1980)
Stocks ( 2 )
Bloomington	967 Df(1)C246/FM6
Kyoto	106693 Df(1)C246/FM6
Notes on Origin
Discoverer	Lefevre.

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 6 )
Reported As
Symbol Synonym	967 (Rikhy et al., 2003) C246 (Yamaguchi et al., 1999, Sanchez et al., 1994) Df(1)c246 (Marenda et al., 2004) Df(1)C246 (Crest et al., 2007, Secombe et al., 2007) Df(1)C²⁴⁶ (Sanyal and Krishnan, 2001) Df(2L)C246 (Li and Li, 2003)
Name Synonym
Secondary FlyBase IDs

References ( 46 )

Generate a list of	All references relating to this aberration ( 46 )

List References by type	Research paper ( 40 ) Personal communication to FlyBase ( 1 ) Abstract ( 3 ) FlyBase analysis ( 1 ) Book ( 1 )
Recent research papers (0)
	All research papers listed in FlyBase were published before 2011 Show research papers ...