Aberration Dmel\Df(1)GA56

General Information
Symbol	Dmel\Df(1)GA56	Species	D. melanogaster
Name		FlyBase ID	FBab0000403
Feature type	chromosomal_deletion

Computed Breakpoints include	4C6;4D1
Deleted segment	4C6--4D1
Map ( GBrowse )	Untitled Document Error No matching regions found.
Sequence coordinates	X:4,386,538..4,390,113 [+] (Df(1)GA56:bk1) (Pflugfelder et al., 1990, Pflugfelder et al., 1992)
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Aberration
Cytological Order
Progenitor
Mutagen	X ray
Class of aberration (relative to progenitor)	chromosomal_deletion (Pauli et al., 1995)
Breakpoints	4C5-4C6;4D1 (Pauli et al., 1995)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	lac << bk1 << bi << peb << bk2 << ovo
Genetic mapping information
Comments	Breakpoint(s) molecularly mapped (Pflugfelder et al., 1990, Pflugfelder et al., 1991)
Comments on Cytology
	Left limit of break 1 from non-inclusion of lac (FBrf0043953) Right limit of break 1 from inclusion of amb (FBrf0043953) Limits of break 2 from polytene analysis (FBrf0080317)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	amb (Banga et al., 1986, Oliver et al., 1988) bi (Banga et al., 1986, Oliver et al., 1988, Pflugfelder et al., 1990) peb (Oliver et al., 1988) rb (Lawlor, 1980, Banga et al., 1986, Oliver et al., 1988, Pflugfelder et al., 1990)
Molecular Data
Completely deleted	rap (Sigrist and Lehner, 1997)
Genes NOT Deleted / Disrupted
Complementation Data
	brn (Oliver et al., 1988) cho (Oliver et al., 1988) cv (Oliver et al., 1988) ec (Oliver et al., 1988) fs(1)A456 (Oliver et al., 1988) fs(1)A1059 (Oliver et al., 1988) lac (Banga et al., 1986, Oliver et al., 1988, Pflugfelder et al., 1990) mei-9 (Banga et al., 1986, Oliver et al., 1988) norpA (Oliver et al., 1988, Pflugfelder et al., 1990, Banga et al., 1986) ovo (Oliver et al., 1988) rg (Oliver et al., 1988) snf (Oliver et al., 1988)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations	In(1)omb-H31/Df(1)GA56 phenotypically lac⁺ In(1)omb-H31/Df(1)GA56 phenotypically bi⁺ In(1)omb-H31/Df(1)GA56 phenotypically rb⁺ Df(1)GA56/T(1;2)bi^D2 lethal Df(1)GA56/T(1;2)bi^D1T lethal Df(1)GA56/bi¹ lethal Df(1)GA56/bi² lethal Df(1)GA56/bi^D4 lethal (Pflugfelder et al., 1990)
NOT in combination with other aberrations	Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovo^D2. (Pauli et al., 1995)
Stocks ( 0 )

Notes on Origin
Discoverer	Lefevre.

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments
	Has a mutation in the same gene that is lethally mutated in T(1;3)bi^D1T, T(1;3)bi^D1T and bi alleles. (Pflugfelder et al., 1990)
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	Df(1)GA56
Name Synonym
Secondary FlyBase IDs

References ( 13 )
Research paper	Shamloula et al., 2002, Genetics 161(2): 693--710 rugose (rg), a Drosophila A kinase anchor protein, is required for retinal pattern formation and interacts genetically with multiple signaling pathways. [FBrf0149022] Sigrist and Lehner, 1997, Cell 90(4): 671--681 Drosophila fizzy-related down-regulates mitotic cyclins and is required for cell proliferation arrest and entry into endocycles. [FBrf0098351] Pauli et al., 1995, Genetics 139(2): 713--732 Identification of regions interacting with ovo^D mutations: Potential new genes involved in germline sex determination or differentiation in Drosophila melanogaster. [FBrf0080317] Pauli et al., 1995, D. I. S. 76: 107--124 Dose dependent enhancers and suppressors of ovoD2. [FBrf0082455] Poeck et al., 1993, Mol. Gen. Genet. 238(3): 325--332 Transcript identification in the optomotor-blind locus of Drosophila melanogaster by intragenic recombination mapping and PCR-aided sequence analysis of lethal point mutations. [FBrf0059076] Pflugfelder et al., 1992, Proc. Natl. Acad. Sci. U.S.A. 89: 1199--1203 The lethal(1)optomotor-blind gene of Drosophila melanogaster is a major organizer of optic lobe development: isolation and characterization of the gene. [FBrf0057510] Pflugfelder et al., 1990, Genetics 126: 91--104 Genetic and molecular characterization of the optomotor-blind gene locus in Drosophila melanogaster. [FBrf0051990] Oliver et al., 1988, Genetics 120: 159--171 Genetic evidence that the sans fille locus is involved in Drosophila sex determination. [FBrf0048195] Banga et al., 1986, Chromosoma 93: 341--346 Cytogenetic characterization of the 4BC region on the X chromosome of Drosophila melanogaster: localization of the mei-9, norpA and omb genes. [FBrf0043953] Lawlor, 1980, D. I. S. 55: 81--82 Genetic and cytological localization of mei-9. [FBrf0034483]
Abstract	Pflugfelder et al., 1991, Greenspan, Palka, 1991: 143 Gene products of the l(1) optomotor-blind gene of Drosophila melanogaster are essential for correct brain and wing development. [FBrf0053304]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]
Book	Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster. The Genome of Drosophila melanogaster. [FBrf0066905]

Aberration Dmel\Df(1)GA56

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