FB2025_01 , released February 20, 2025
Aberration: Dmel\Df(1)JA27
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General Information
Symbol
Df(1)JA27
Species
D. melanogaster
Name
FlyBase ID
FBab0000464
Feature type
chromosomal_deletion
Also Known As
JA27
Computed Breakpoints include

18A5;18D1

Features within 18A5--18D1
Genomic Maps
Sequence coordinates
X:19,149,609..19,149,609 (Df(1)JA27:bk1)
(Miller et al., 2016)
X:19,505,829..19,505,829 (Df(1)JA27:bk2)
(Miller et al., 2016)
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
X ray
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Holmes et al., 1998, Cook et al., 1997, Duffy et al., 1996, Pauli et al., 1995, Anand and Chandra, 1994, Ferrus et al., 1990, Thomas and Wyman, 1984, Deak et al., 1982, Craymer and Roy, 1980)
Breakpoints

18A5;18D1-18D2

(Duffy et al., 1996, Craymer and Roy, 1980)

18A;18D

(Deak et al., 1982)

18A5;18D1

(Thomas and Wyman, 1984)

18A4-18A5;18D1-18D2

(Ferrus et al., 1990)

18A5;20A

(Cook et al., 1997, Pauli et al., 1995, Anand and Chandra, 1994)

18A;18D;19F;20

(Fehon et al., 1997)

18A5;18D

(Holmes et al., 1998)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

bk1 << knax << jok << bk2 << car

Genetic mapping information
Comments

FlyBase curator comment: genomic coordinates updated from release 5 coordinates ( X:19 ,043,642..19,399,862) given in paper.

(Miller et al., 2016)

This deletion removes a single ribosomal protein-coding gene (though other genes are also removed).

(Marygold et al., 2007)
Comments on Cytology

Limits of break 1 from polytene analysis (FBrf0034402) Left limit of break 2 from polytene analysis (FBrf0034402) Right limit of break 2 from polytene analysis (FBrf0041358)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
jok
(Holmes et al., 1998)
knax
(Holmes et al., 1998)
nAChRα7
(Thomas and Wyman, 1984)
out
(Coffman et al., 2002)
tur
(Choi et al., 1991)
Partially deleted / disrupted
Molecular Data
Completely deleted
mRpS14
(Marygold et al., 2007)
pcm
(Lin et al., 2008)
Partially deleted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (45)
Phenotypic Data
In combination with other aberrations

Transmission rate of Dp(1;f)J21A through females to progeny is 28%, Df(1)JA27 has no effect on transmission.

(Cook et al., 1997)
NOT in combination with other aberrations

Flies heterozygous for the deletion do not show a Minute bristle phenotype.

(Marygold et al., 2007)

Does not cause unconditional lethality in hybrid females when heterozygous with D.simulans chromosome.

(Coyne et al., 1998)

No second site non-complementing phenotype with zipEbr and zipmhc-c6.1.

(Halsell and Kiehart, 1998)

Shows no maternal enhancement of dpphr4.

(Nicholls and Gelbart, 1998)

Dominantly causes tergite defects in less than 50% of run3 heterozygotes.

(Duffy et al., 1996)

Deficient embryos show an uninterpretable mutant midgut phenotype.

(Bilder and Scott, 1995)

Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovoD2.

(Pauli et al., 1995)

No significant change in female lethality when in combination with Sxlf1.

(Anand and Chandra, 1994)

Heterozygotes with gfA1 or nAChRalpha72 display the nAChRalpha7 physiological phenotype.

(Thomas and Wyman, 1984)
Stocks (4)
Notes on Origin
Discoverer

Lefevre.

 
Balancer / Genotype Variants of the Aberration
 
Separable Components
 
Other Comments
 
Synonyms and Secondary IDs (2)
References (37)