FlyBase Aberration Report: Dmel\Df(1)JC70

General Information

Symbol

Df(1)JC70

Species

D. melanogaster

Name

FlyBase ID

FBab0000474

Feature type

chromosomal_deletion

Computed Breakpoints include

4C11-4C12;5A3-5A4

Features within 4C11--5A4

Genomic Maps

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Sequence coordinates

X:4,679,537..4,919,558 (Df(1)JC70:bk1)

(Cook, 2016.2.8)

X:5,309,242..5,412,386 (Df(1)JC70:bk2)

(Cook, 2016.2.8)

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

Progenitor

Mutagen

X ray

(Eeken and Sobels, 1990)

Class of aberration (relative to wild type)

chromosomal_deletion

(FlyBase, 2007)

Class of aberration (relative to progenitor)

chromosomal_deletion

(Cook et al., 1997, Han et al., 1997, Duffy et al., 1996, Harbecke and Lengyel, 1995, Salz, 1992, Eeken and Sobels, 1990, Craymer and Roy, 1980)

Breakpoints

4C15-4C16;5A1-5A2

(Cook et al., 1997, Duffy et al., 1996, Harbecke and Lengyel, 1995, Eeken and Sobels, 1990, Craymer and Roy, 1980)

4C11-4C12;5A3-5A4

(Salz, 1992)

4C5-4C6;5A1-5A2

(Han et al., 1997)

Causes alleles

Carries alleles

Transposon Insertions

Formalized genetic data

rap << bk1 << l(1)4Da << bk2 << cx

Genetic mapping information

Comments

The X:4679537..4919558 release 6 coordinates of the left breakpoint are estimates. The left extent corresponds to the right end of rap, which published results say is not deleted. The right extent corresponds to the rightmost end of a PCR primer pair flanking the insertion site of P{EPgy2}CG6903^EY08878 from Table S1 of FBrf0212582, which did not amplify a DNA segment from Df(1)JC70 in tests at the Bloomington Stock Center.

(Cook, 2016.2.8)

The X:5309242..5412386 release 6 coordinates of the right breakpoint are estimates. The left extent corresponds to the left end of snf, which published results say is deleted. The right extent corresponds to the left end of spoon, which published results say is not deleted.

(Cook, 2016.2.8)

Comments on Cytology

Deletion of 22/28 bands.

(Eeken and Sobels, 1990)

All limits from polytene analysis (FBrf0056236)

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

fs(1)A456

(Salz, 1992, Oliver et al., 1988)

fs(1)A1059

(Salz, 1992, Oliver et al., 1988)

(Schalet, 1986)

(Salz, 1992)

(Salz, 1992)

(Laurencon, 2001.7.21)

ovo

(Harbecke and Lengyel, 1995, Salz, 1992, Oliver et al., 1988)

(Han et al., 1997, Salz, 1992, Oliver et al., 1988, Craymer and Roy, 1980)

snf

(Granadino et al., 1992, Salz, 1992, Oliver et al., 1988)

Partially deleted / disrupted

Molecular Data

Completely deleted

Partially deleted

Genes NOT Deleted / Disrupted

Complementation Data

amb

(Oliver et al., 1988)

(Oliver et al., 1988, Schalet, 1986)

brn

(Oliver et al., 1988)

ctp

(Ghosh-Roy et al., 2004)

(Oliver et al., 1988, Schalet, 1986)

(Schalet, 1986, Craymer and Roy, 1980)

(Oliver et al., 1988, Schalet, 1986)

fs(1)se

(Perez-Chiesa et al., 1983)

(Schalet, 1986)

(Schalet, 1986)

(Schalet, 1986)

(Schalet, 1986)

(Schalet, 1986)

(Schalet, 1986)

(Schalet, 1986)

(Schalet, 1986)

(Oliver et al., 1988)

mei-9

(Oliver et al., 1988)

norpA

(Oliver et al., 1988)

peb

(Oliver et al., 1988, Tearle and Nusslein-Volhard, 1987, Schalet, 1986)

PpV

(Liu et al., 2019)

qed

(Florence, 1999.7.22)

(Oliver et al., 1988, Schalet, 1986, Craymer and Roy, 1980)

rux

(Schalet, 1986)

spoon

(Hadad et al., 2011)

VhaAC39-1

(Oliver et al., 1988, Schalet, 1986)

Molecular Data

fzr

(Sigrist and Lehner, 1997)

Genes Duplicated

Complementation Data

Completely duplicated

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Affected Genes Inferred by Location

Related Comments

Df(1)JC70 complements the “ew” trait of ctp alleles.

(Ghosh-Roy et al., 2004)

Phenotypic Data

In combination with other aberrations

Inferred to overlap with: Df(1)Exel6234.

(Haussmann et al., 2013)

Mated Df(1)JC70/Df(1)Exel6234 females behave like virgins. They fail to decrease receptivity (readiness to mate) compared with wild-type mated controls. They show somewhat decreased oviposition compared with mated wild-type females.

(Haussmann et al., 2013)

Transmission rate of Dp(1;f)J21A through females to progeny is 28%, Df(1)JC70 weakly decreases transmission.

(Cook et al., 1997)

NOT in combination with other aberrations

Uncovers Dsec\ovo in D.melanogaster/D.sechellia hybrids.

(Sucena and Stern, 2000)

Does not cause unconditional lethality in hybrid females when heterozygous with D.simulans chromosome.

(Coyne et al., 1998)

Intermediate second site non-complementing phenotype with zip^Ebr and zip^mhc-c6.1 : malformed phenotype penetrance 25-75%.

(Halsell and Kiehart, 1998)

Shows no maternal enhancement of dpp^hr4.

(Nicholls and Gelbart, 1998)

Dominantly causes tergite defects in less than 50% of run³ heterozygotes.

(Duffy et al., 1996)

Midgut development of mutant embryos is wild type.

(Bilder and Scott, 1995)

Hemizygous embryos were examined with polarised light microscopy and antibody staining and found to have wild type muscle pattern and contraction.

(Drysdale et al., 1993)

Heterozygous females exhibit reduced viability and fertility.

(Eeken and Sobels, 1990)

Stocks (5)

Bloomington

944

Df(1)JC70/FM7c, sn⁺

5279

Df(1)JC70/Dp(1;Y)dx⁺5, y⁺/C(1)M5

Kyoto

108924

Df(1)JC70/FM7c, sn⁺

108145

Df(1)JC70/Dp(1;Y)dx⁺5, y⁺/C(1)M5

103246

Df(1)JC70 / FM7c, y^31d sc⁸ w^a sn^X2 v^Of g⁴ B¹

Notes on Origin

Discoverer

Lefevre.

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Df(1)JC70

(Li et al., 2020, Sawyer et al., 2020, Tirmarche et al., 2016, Haussmann et al., 2013, Hadad et al., 2011, Wang et al., 2011, Silies and Klämbt, 2010, Crest et al., 2007, Jordan et al., 2006)

Df(1)Jc70

(Ghosh-Roy et al., 2004)

JC70

(Sanchez et al., 1994)

Name Synonyms

Secondary FlyBase IDs

References (51)

Report Sections

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