Aberration Dmel\Df(1)JC70

General Information
Symbol	Dmel\Df(1)JC70	Species	D. melanogaster
Name		FlyBase ID	FBab0000474
Feature type	chromosomal_deletion

Computed Breakpoints include	4C11-4C12;5A3-5A4
Deleted segment	4C11--5A4
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor
Mutagen	X ray (Eeken and Sobels, 1990)
Class of aberration (relative to progenitor)	chromosomal_deletion (Salz, 1992, Duffy et al., 1996, Cook et al., 1997, Harbecke and Lengyel, 1995, Han et al., 1997, Eeken and Sobels, 1990, Craymer and Roy, 1980)
Breakpoints	4C5-4C6;5A1-5A2 (Han et al., 1997) 4C11-4C12;5A3-5A4 (Salz, 1992) 4C15-4C16;5A1-5A2 (Craymer and Roy, 1980, Eeken and Sobels, 1990, Harbecke and Lengyel, 1995, Duffy et al., 1996, Cook et al., 1997)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	rap << bk1 << l(1)4Da << bk2 << cx
Genetic mapping information
Comments
Comments on Cytology
	Deletion of 22/28 bands. (Eeken and Sobels, 1990) All limits from polytene analysis (FBrf0056236)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	fs(1)A456 (Oliver et al., 1988, Salz, 1992) fs(1)A1059 (Oliver et al., 1988, Salz, 1992) l(1)4Da (Schalet, 1986) l(1)4Ea (Salz, 1992) l(1)4Fa (Salz, 1992) mus108 (Laurencon, 2001.7.21) ovo (Oliver et al., 1988, Salz, 1992, Harbecke and Lengyel, 1995) rg (Craymer and Roy, 1980, Oliver et al., 1988, Salz, 1992, Han et al., 1997) snf (Oliver et al., 1988, Salz, 1992, Granadino et al., 1992)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	amb (Oliver et al., 1988) bi (Schalet, 1986, Oliver et al., 1988) brn (Oliver et al., 1988) cho (Schalet, 1986, Oliver et al., 1988) ctp (Ghosh-Roy et al., 2004) cv (Schalet, 1986, Oliver et al., 1988) cx (Craymer and Roy, 1980, Schalet, 1986) ec (Schalet, 1986, Oliver et al., 1988) fs(1)se (Perez-Chiesa et al., 1983) l(1)4ACa (Schalet, 1986) l(1)4Ca (Schalet, 1986) l(1)5Aa (Schalet, 1986) l(1)5ACa (Schalet, 1986) l(1)5ACb (Schalet, 1986) l(1)5AEa (Schalet, 1986) l(1)5Da (Schalet, 1986) l(1)5DEa (Schalet, 1986) lac (Oliver et al., 1988) mei-9 (Oliver et al., 1988) norpA (Oliver et al., 1988) peb (Schalet, 1986, Tearle and Nusslein-Volhard, 1987, Oliver et al., 1988) qed (Florence, 1999.7.22) rb (Craymer and Roy, 1980, Schalet, 1986, Oliver et al., 1988) rux (Schalet, 1986) spoon (Hadad et al., 2011)
Molecular Data
	rap (Sigrist and Lehner, 1997)
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments
	Df(1)JC70 complements the “ew” trait of ctp alleles. (Ghosh-Roy et al., 2004)
Phenotypic Data
In combination with other aberrations	Transmission rate of Dp(1;f)J21A through females to progeny is 28%, Df(1)JC70 weakly decreases transmission. (Cook et al., 1997)
NOT in combination with other aberrations	Uncovers Dsec\ovo in D.melanogaster/D.sechellia hybrids. (Sucena and Stern, 2000) Does not cause unconditional lethality in hybrid females when heterozygous with D.simulans chromosome. (Coyne et al., 1998) Intermediate second site non-complementing phenotype with zip^Ebr and zip^mhc-c6.1: malformed phenotype penetrance 25-75%. (Halsell and Kiehart, 1998) Shows no maternal enhancement of dpp^hr4. (Nicholls and Gelbart, 1998) Dominantly causes tergite defects in less than 50% of run³ heterozygotes. (Duffy et al., 1996) Midgut development of mutant embryos is wild type. (Bilder and Scott, 1995) Hemizygous embryos were examined with polarised light microscopy and antibody staining and found to have wild type muscle pattern and contraction. (Drysdale et al., 1993) Heterozygous females exhibit reduced viability and fertility. (Eeken and Sobels, 1990)
Stocks ( 5 )
Bloomington	944 Df(1)JC70/FM7c, sn⁺ 5279 Df(1)JC70/Dp(1;Y)dx⁺5, y⁺/C(1)M5
Kyoto	108924 Df(1)JC70/FM7c, sn⁺ 108145 Df(1)JC70/Dp(1;Y)dx⁺5, y⁺/C(1)M5 103246 Df(1)JC70 / FM7c, y^31d sc⁸ w^a sn^X2 v^Of g⁴ B¹
Notes on Origin
Discoverer	Lefevre.

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	Df(1)Jc70 (Ghosh-Roy et al., 2004) Df(1)JC70 (Jordan et al., 2006, Crest et al., 2007, Hadad et al., 2011, Wang et al., 2011, Silies and Klämbt, 2010) JC70 (Sanchez et al., 1994)
Name Synonym
Secondary FlyBase IDs

References ( 44 )

Generate a list of	All references relating to this aberration ( 44 )

List References by type	Research paper ( 38 ) Supplementary material ( 1 ) Personal communication to FlyBase ( 2 ) FlyBase analysis ( 1 ) Stock list ( 1 ) Book ( 1 )
Recent research papers ( 2 )
	Hadad et al., 2011, Mech. Dev. 128(7-10): 471--482 Drosophila spoonbill encodes a dual-specificity A-kinase anchor protein essential for oogenesis. [FBrf0216765] Wang et al., 2011, Dev. Cell 21(3): 520--533 An ana2/ctp/mud complex regulates spindle orientation in Drosophila neuroblasts. [FBrf0215580] Show all research papers ...