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General Information
Symbol
Df(1)JC70
Species
D. melanogaster
Name
FlyBase ID
FBab0000474
Feature type
Computed Breakpoints include

4C11-4C12;5A3-5A4

Deleted Segment
Sequence coordinates
X:4,679,537..4,919,558 (Df(1)JC70:bk1)
X:5,309,242..5,412,386 (Df(1)JC70:bk2)
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Class of aberration (relative to wild type)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

rap << bk1 << l(1)4Da << bk2 << cx

Genetic mapping information
Comments

The X:4679537..4919558 release 6 coordinates of the left breakpoint are estimates. The left extent corresponds to the right end of rap, which published results say is not deleted. The right extent corresponds to the rightmost end of a PCR primer pair flanking the insertion site of P{EPgy2}CG6903EY08878 from Table S1 of FBrf0212582, which did not amplify a DNA segment from Df(1)JC70 in tests at the Bloomington Stock Center.

The X:5309242..5412386 release 6 coordinates of the right breakpoint are estimates. The left extent corresponds to the left end of snf, which published results say is deleted. The right extent corresponds to the left end of spoon, which published results say is not deleted.

Comments on Cytology

Deletion of 22/28 bands.

All limits from polytene analysis (FBrf0056236)

Sequence Crossreferences
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Phenotypic Data
In combination with other aberrations

Inferred to overlap with: Df(1)Exel6234.

Mated Df(1)JC70/Df(1)Exel6234 females behave like virgins. They fail to decrease receptivity (readiness to mate) compared with wild-type mated controls. They show somewhat decreased oviposition compared with mated wild-type females.

Transmission rate of Dp(1;f)J21A through females to progeny is 28%, Df(1)JC70 weakly decreases transmission.

NOT in combination with other aberrations

Does not cause unconditional lethality in hybrid females when heterozygous with D.simulans chromosome.

Intermediate second site non-complementing phenotype with zipEbr and zipmhc-c6.1 : malformed phenotype penetrance 25-75%.

Shows no maternal enhancement of dpphr4.

Dominantly causes tergite defects in less than 50% of run3 heterozygotes.

Midgut development of mutant embryos is wild type.

Hemizygous embryos were examined with polarised light microscopy and antibody staining and found to have wild type muscle pattern and contraction.

Heterozygous females exhibit reduced viability and fertility.

Stocks (5)
Notes on Origin
Discoverer

Lefevre.

 
Balancer / Genotype Variants of the Aberration
 
Separable Components
 
Other Comments
 
Synonyms and Secondary IDs (3)
References (48)