FB2025_01 , released February 20, 2025
Aberration: Dmel\Df(1)KA14
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General Information
Symbol
Df(1)KA14
Species
D. melanogaster
Name
FlyBase ID
FBab0000483
Feature type
chromosomal_deletion
Computed Breakpoints include

7F1;8C6

Features within 7F1--8C6
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
X ray
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Porsch et al., 1998, Cook et al., 1997, Min and Benzer, 1997, Duffy et al., 1996, Harbecke and Lengyel, 1995, Pauli et al., 1995, Anand and Chandra, 1994, Landecker et al., 1994, Spradling et al., 1994, Silva et al., 1991, Watson et al., 1991, Bieber et al., 1989, Helfand and Carlson, 1989, Inoue et al., 1989, Perrimon et al., 1989, King et al., 1986, Lineruth et al., 1985, Wieschaus et al., 1984, Deak et al., 1982, Craymer and Roy, 1980)
Breakpoints

7F1-7F2;8C6

(Porsch et al., 1998, Cook et al., 1997, Duffy et al., 1996, Harbecke and Lengyel, 1995, Pauli et al., 1995, Anand and Chandra, 1994, Landecker et al., 1994, Wojcik et al., 1994, Smith et al., 1993, Silva et al., 1991, Watson et al., 1991, Inoue et al., 1989, Perrimon et al., 1989, King et al., 1986, Lineruth et al., 1985, Wieschaus et al., 1984, Deak et al., 1982, Craymer and Roy, 1980)

7D10-7D11;8C6

(Spradling et al., 1994)

7F1-7F2;8C5

(Bieber et al., 1989)

7F1;8C6

(Min and Benzer, 1997, Helfand and Carlson, 1989)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

lix << bk1 << su(Cbx) << l(1)7Fd << bk2 << fliD

Genetic mapping information
Comments
Comments on Cytology

Ref: Craymer and Roy, 1980, D. I. S. 55: 200--204

(Wieschaus et al., 1984)

Left limit of break 1 from polytene analysis (FBrf0034402) Right limit of break 1 from inclusion of Nrg (FBrf0044177) Limits of break 2 from polytene analysis (FBrf0034402)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
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    Phenotypic Data
    In combination with other aberrations

    Transmission rate of Dp(1;f)J21A through females to progeny is 28%, Df(1)KA14 has no effect on transmission.

    (Cook et al., 1997)
    NOT in combination with other aberrations

    Shows dominant enhancement of dominant haltere phenotype caused by Ubx195 and Ubx9.22.

    (Burnette et al., 1999)

    Does not cause unconditional lethality in hybrid females when heterozygous with D.simulans chromosome.

    (Coyne et al., 1998)

    No second site non-complementing phenotype with zipEbr and zipmhc-c6.1.

    (Halsell and Kiehart, 1998)

    Shows no maternal enhancement of dpphr4.

    (Nicholls and Gelbart, 1998)

    Most of the VUM neurons and also the median neuroblast degenerate. Midline glial cells fail to migrate posteriorly, but this may be an indirect effect due to the absence of VUM neurons. Dorsal medial cell numbers correspond to wild type. Thus midline neurons appear to be dispensible with regard to dorsal meidal cell formation.

    (Luer et al., 1997)

    Dominantly causes tergite defects in less than 50% of run3 heterozygotes.

    (Duffy et al., 1996)

    Midgut development of mutant embryos is wild type.

    (Bilder and Scott, 1995)

    Homozygous embryos have reduced heads compared to wild-type.

    (Harbecke and Lengyel, 1995)

    Heterozygosity for this deletion enhances the mutant ovarian phenotype of ovoD2.

    (Pauli et al., 1995)

    The Bolwig organ, hypopharyngeal organ and laterohypopharyngeal organ are absent in homozygous embryos. The frontal ganglion and frontal connective are shifted anteriorly. The supraoesophageal ganglion is reduced in size and no supraoesophageal commissure forms. The optic lobes are almost completely deleted.

    (Schmidt-Ott et al., 1995)

    More than six-fold reduction in sex ratio and significant levels of female lethality is observed when in combination with Sxlf1. Female lethality is also reduced when in combination with da1 but restored when in combination with emcML.

    (Anand and Chandra, 1994)

    Ocular segment, dorsomedial papilla, pharyngeal sense organ, Bolwig's organ, antennal sense organ and pharyngeal monoscolopidial chordotonal organ are deleted.

    (Schmidt-Ott et al., 1994)

    Hemizygous embryos were examined with polarised light microscopy and antibody staining: indistinct striations and altered staining properties in antibody assay.

    (Drysdale et al., 1993)

    Heterozygotes have ocelli placed far back on the head and there is a slight indentation in the cuticle beneath the postvertical bristles.

    (Craymer and Roy, 1980)

    Germ-line clones lethal (Garcia-Bellido and Robbins, 1983, Genetics 103: 235-47)

    Stocks (2)
    Notes on Origin
    Discoverer

    Lefevre.

     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (6)
    References (68)