|Computed Breakpoints include||7F1;8C6|
|Member of large scale dataset(s)|
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|Nature of the Aberration|
|Class of aberration (relative to progenitor)|
(Perrimon et al., 1989, Spradling et al., 1994, Wieschaus et al., 1984, Deak et al., 1982, Bieber et al., 1989, Pauli et al., 1995, Duffy et al., 1996, King et al., 1986, Silva et al., 1991, Lineruth et al., 1985, Helfand and Carlson, 1989, Inoue et al., 1989, Cook et al., 1997, Watson et al., 1991, Harbecke and Lengyel, 1995, Landecker et al., 1994, Anand and Chandra, 1994, Min and Benzer, 1997, Craymer and Roy, 1980, Porsch et al., 1998)
(Craymer and Roy, 1980, Deak et al., 1982, Wieschaus et al., 1984, Lineruth et al., 1985, King et al., 1986, Perrimon et al., 1989, Inoue et al., 1989, Watson et al., 1991, Silva et al., 1991, Smith et al., 1993, Landecker et al., 1994, Wojcik et al., 1994, Anand and Chandra, 1994, Pauli et al., 1995, Harbecke and Lengyel, 1995, Duffy et al., 1996, Cook et al., 1997, Porsch et al., 1998)
|Formalized genetic data||lix << bk1 << su(Cbx) << l(1)7Fd << bk2 << fliD|
|Genetic mapping information|
|Comments on Cytology|
Ref: Craymer and Roy, 1980, D. I. S. 55: 200--204
|Gene Deletion & Duplication Data|
|Genes Deleted / Disrupted|
|Completely deleted / disrupted|
|Genes NOT Deleted / Disrupted|
|Genes NOT Duplicated|
|In combination with other aberrations|
|NOT in combination with other aberrations|
Does not cause unconditional lethality in hybrid females when heterozygous with D.simulans chromosome.
Most of the VUM neurons and also the median neuroblast degenerate. Midline glial cells fail to migrate posteriorly, but this may be an indirect effect due to the absence of VUM neurons. Dorsal medial cell numbers correspond to wild type. Thus midline neurons appear to be dispensible with regard to dorsal meidal cell formation.
Midgut development of mutant embryos is wild type.
Homozygous embryos have reduced heads compared to wild-type.
Heterozygosity for this deletion enhances the mutant ovarian phenotype of ovoD2.
The Bolwig organ, hypopharyngeal organ and laterohypopharyngeal organ are absent in homozygous embryos. The frontal ganglion and frontal connective are shifted anteriorly. The supraoesophageal ganglion is reduced in size and no supraoesophageal commissure forms. The optic lobes are almost completely deleted.
More than six-fold reduction in sex ratio and significant levels of female lethality is observed when in combination with Sxlf1. Female lethality is also reduced when in combination with da1 but restored when in combination with emcML.
Ocular segment, dorsomedial papilla, pharyngeal sense organ, Bolwig's organ, antennal sense organ and pharyngeal monoscolopidial chordotonal organ are deleted.
Hemizygous embryos were examined with polarised light microscopy and antibody staining: indistinct striations and altered staining properties in antibody assay.
Heterozygotes have ocelli placed far back on the head and there is a slight indentation in the cuticle beneath the postvertical bristles.
Germ-line clones lethal (Garcia-Bellido and Robbins, 1983, Genetics 103: 235-47)
|Stocks ( 2 )|
|Notes on Origin|
|Balancer / Genotype Variants of the Aberration|
|Synonyms & Secondary IDs ( 6 )|
|Secondary FlyBase IDs|
|References ( 68 )|
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|List References by type|
|Recent research papers (0)|
|All research papers listed in FlyBase were published before 2011|