|Computed Breakpoints include||10E1;11A7|
|Member of large scale dataset(s)|
What does this section display?
This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).
What does this section not display?
This section does not currently display links that were removed or gene model changes.
Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
|All updates||Click here to see a list of all updates to this record from FB2010_08 and on.|
|Nature of the Aberration|
|Class of aberration (relative to progenitor)|
|Formalized genetic data||Rst(1)JH << bk1 << l(1)10Fk << l(1)10Ea << bk2 << gs(1)N41|
|Genetic mapping information|
Breakpoint(s) molecularly mapped
|Comments on Cytology|
Deletion of 22/24 bands.
All limits from polytene analysis (FBrf0034402)
|Gene Deletion & Duplication Data|
|Genes Deleted / Disrupted|
|Completely deleted / disrupted|
|Genes NOT Deleted / Disrupted|
|Genes NOT Duplicated|
|In combination with other aberrations|
|NOT in combination with other aberrations|
Df(1)KA6 hemizygous embryos exhibit head and thorax defects similar to tsg loss of function mutants. With a very low penetrance, Df(1)KA6 hemizygous embryos show subtle defects in segmentation, including partial fusion of denticle band pairs in the register seen for Ten-m mutants. Flies with transheterozygous combinations of Df(1)KA6/+ and Ten-m/+ display eye roughness. Consistent features include ommatidial order defects, ommatidial fusions, eye sensory bristle loss, and occasional supernumerary sensory bristles.
Hemizygous late embryonic lethal.
Acts as a dosage sensitive maternal modifier of run: causes tergite defects in greater than 50% of run3 heterozygotes. Maternal heterozygosity for Df(1)KA6 greatly increases the frequency of segmentation defects in embryos heterozygous for eve, run and Kr.
Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovoD2.
Heterozygous females exhibit reduced viability and fertility.
|Stocks ( 2 )|
|Notes on Origin|
|Balancer / Genotype Variants of the Aberration|
|Synonyms & Secondary IDs ( 3 )|
|Secondary FlyBase IDs|
|References ( 29 )|
|Generate a list of|
|List References by type|
|Recent research papers (0)|
|All research papers listed in FlyBase were published before 2011|