Aberration Dmel\Df(1)LB6

General Information
Symbol	Dmel\Df(1)LB6	Species	D. melanogaster
Name		FlyBase ID	FBab0000496
Feature type	chromosomal_deletion
Also Known As	LB6

Computed Breakpoints include	19E2-19E4;20A2-20A3
Deleted segment	19E2--20A3
Map ( GBrowse )	Untitled Document Error No matching regions found.
Sequence coordinates	X:20,650,741..20,651,741 [-] (Df(1)LB6:bk1) (Crompton et al., 1995)
Member of large scale dataset(s)
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor
Mutagen	mitomycin C (Schalet and Lefevre, 1973)
Class of aberration (relative to progenitor)	chromosomal_deletion (Schalet and Lefevre, 1973)
Breakpoints	19E4;20A2-20A3 (Schalet and Lefevre, 1973)
Causes alleles	shakB^LB6 (Crompton et al., 1995)
Carries alleles
Transposon Insertions
Formalized genetic data	bk1 hits shakB << flam << bk2 << wap
Genetic mapping information
Comments	Df(1)LB6 distal breakpoint maps to the long intron between exons B and D of shakB transcript S2.2. (Crompton et al., 1995)
Comments on Cytology
	Left limit of break 1 from non-inclusion of mell (FBrf0049891) Right limit of break 1 from inclusion of l(1)19Ec (FBrf0049891) Limits of break 2 from polytene analysis (FBrf0024685)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	COM (Desset et al., 2003) eo (Robert et al., 2001, Schalet and Lefevre, 1973, Perrimon et al., 1989, Prud'homme et al., 1995) flam (Robert et al., 2001, Prud'homme et al., 1995) fliI (Perrimon et al., 1989) Hlc (Perrimon et al., 1989, Prud'homme et al., 1995) l(1)19Ed (Perrimon et al., 1989, Torres and Sanchez, 1992) l(1)19Fb (Perrimon et al., 1989) lf (Perrimon et al., 1989, Torres and Sanchez, 1992) lfl (Perrimon et al., 1989) mst (Perrimon et al., 1989, Prud'homme et al., 1995) Npc1b (Torres and Sanchez, 1992, Perrimon et al., 1989) shakB (Schalet and Lefevre, 1973, Perrimon et al., 1989, Torres and Sanchez, 1992, Griffin et al., 1993, Crompton et al., 1995) slgA (Perrimon et al., 1989) sol (Perrimon et al., 1989) tuh1 (Perrimon et al., 1989, Prud'homme et al., 1995) unc (Perrimon et al., 1989) vao (Perrimon et al., 1989, Torres and Sanchez, 1992)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	fog (Perrimon et al., 1989) intro (Schalet and Lefevre, 1973, Perrimon et al., 1989, Prud'homme et al., 1995) l(1)20Ca (Perrimon et al., 1989) l(1)20Cb (Perrimon et al., 1989) l(1)carot2 (Prud'homme et al., 1995) mal (Perrimon et al., 1989) mel (Prud'homme et al., 1995) mell (Perrimon et al., 1989) run (Schalet and Lefevre, 1973, Perrimon et al., 1989, Torres and Sanchez, 1992) soz (Perrimon et al., 1989) sph (Perrimon et al., 1989) stnA (Perrimon et al., 1989) stnB (Perrimon et al., 1989) su(f) (Perrimon et al., 1989, Prud'homme et al., 1995) tilB (Kavlie et al., 2010) uncl (Perrimon et al., 1989) wap (Robert et al., 2001, Schalet and Lefevre, 1973, Perrimon et al., 1989, Prud'homme et al., 1995)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations	Deficiency heterozygotes between Df(1)B12 or Df(1)LB6 and Df(1)R21, Df(1)16-2-13 or Df(1)DCB1-35c are viable, fertile and do not display any visible phenotype. (Prud'homme et al., 1995)
NOT in combination with other aberrations
Stocks ( 2 )
Bloomington	5999 Df(1)LB6/FM6/Dp(1;Y)y⁺mal¹⁰⁶
Kyoto	108539 Df(1)LB6/FM6/Dp(1;Y)y⁺mal¹⁰⁶
Notes on Origin
Discoverer	Baldwin.

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	Df(1)LB6 (Kavlie et al., 2010) LB6 (Robert et al., 2001, Schalet and Lefevre, 1973)
Name Synonym
Secondary FlyBase IDs

References ( 11 )
Research paper	Kavlie et al., 2010, Genetics 185(1): 177--188 Hearing in Drosophila Requires TilB, a Conserved Protein Associated With Ciliary Motility. [FBrf0210892] Desset et al., 2003, Genetics 164(2): 501--509 COM, a heterochromatic locus governing the control of independent endogenous retroviruses from Drosophila melanogaster. [FBrf0160480] Robert et al., 2001, Genetics 158(2): 701--713 Characterization of the flamenco Region of the Drosophila melanogaster Genome. [FBrf0136953] Crompton et al., 1995, Dev. Biol. 170(1): 142--158 Essential and neural transcripts from the Drosophila shaking-B locus are differentially expressed in the embryonic mesoderm and pupal nervous system. [FBrf0081679] Prud'homme et al., 1995, Genetics 139(2): 697--711 flamenco, a gene controlling the gypsy retrovirus of Drosophila melanogaster. [FBrf0080334] Torres and Sanchez, 1992, Genet. Res. (Camb.) 59(3): 189--198 The segmentation gene runt is needed to activate Sex-lethal, a gene that controls sex determination and dosage compensation in Drosophila. [FBrf0056153] Perrimon et al., 1989, Genetics 121: 313--331 Developmental genetics of loci at the base of the X chromosome of Drosophila melanogaster. [FBrf0049891] Schalet and Lefevre, 1973, Chromosoma 44: 183--202 The localization of 'ordinary' sex-linked genes in section 20 of the polytene X chromosome of Drosophila melanogaster. [FBrf0024685]
Abstract	Griffin et al., 1993, J. Neurogenet. 8: 232 Analysis of the genomic region in and around the Shaking-B locus of Drosophila melanogaster. [FBrf0079732]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]
Book	Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster. The Genome of Drosophila melanogaster. [FBrf0066905]

Aberration Dmel\Df(1)LB6

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