A Database of Drosophila Genes & Genomes

FB2008_07, released August 8, 2008
 

Aberration Dmel\Df(1)N-66i25

General Information
SymbolDmel\Df(1)N-66i25SpeciesD. melanogaster
NameDeficiency (1) NotchFlyBase IDFBab0000572
Feature typechromosomal_deletionCreated / Updated2006-08-22/2006-08-22
Formalized genetic data bk1 << w << N << bk2
Sequence coordinates
Deleted segment3C1--3C7
Duplicated segment
Computed Breakpoints include 3C1-3C2;3C7
Breakpoints Inherited  
hide Nature of the Aberration
Cytological Order
Progenitor
Mutagen
spontaneous
 
Class of aberration (relative to progenitor)
chromosomal_deletion
(Welshons, 1974)
Breakpoints
3C1;3C6
(Welshons, 1974)
Causes alleles
Carries alleles
Transposon Insertions
Genetic mapping information
Comments
+0.8 to +2.7 kb The zero coordinate used in locating the molecular lesions in the Notch deficiencies is the first Eco R1 site in Canton-S DNA proximal to the 3C7 breakpoint of In(1)N76b8 (Kidd et al., 1983); it is 1.1 kb to the right of the zero coordinate used by Artavanis-Tsakonas et al., 1983
 
hide Comments on Cytology
Limits of break 1 from polytene analysis (FBrf0026367) Left limit of break 2 from inclusion of N (FBrf0026367) Right limit of break 2 from polytene analysis (citation unavailable)
 
hide Molecularly Mapped Breakpoints
 
hide Sequence Crossreferences
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
hide Gene Deletion & Duplication Data
hide Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
w
(Welshons, 1974)
N
(Welshons, 1974)
rst
(Welshons, 1974)
vt
(Welshons, 1974)
Molecular Data
hide Genes NOT Deleted / Disrupted
Complementation Data
Molecular Data
hide Genes Duplicated
Complementation Data
Molecular Data
hide Genes NOT Duplicated
Complementation Data
Molecular Data
hide Related Comments
hide Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations
hide Position Effect Variegation Data
  
hide Stocks ( 0 )
hide Notes on Origin
Discoverer
Green.
 
Arose in: w8.
 
hide Balancer / Genotype Variants of the Aberration
    hide Separable Components
      hide Other Comments
      hide Synonyms & Secondary IDs ( 5 )
      Reported As
      Symbol Synonym
      Df(1)N-66i25
       
      Df(1)N-66i25,17
       
      Df(1)N66i25
      (Welshons, 1974)
      N66i25
      (Grimwade et al., 1985, Artavanis-Tsakonas et al., 1983)
      Name Synonym
      Deficiency (1) Notch
       
      Secondary FlyBase IDs
        hide References ( 8 )
        Research paper
        Grimwade et al., 1985, Dev. Biol. 107: 503--519
        The molecular genetics of the Notch locus in Drosophila melanogaster. [FBrf0042381]
        Artavanis-Tsakonas et al., 1983, Proc. Natl. Acad. Sci. USA 80: 1977--1981
        Molecular cloning of Notch, a locus affecting neurogenesis in Drosophila melanogaster. [FBrf0040118]
        Kidd et al., 1983, Cell 34: 421--433
        The Notch locus of Drosophila melanogaster. [FBrf0039003]
        Welshons and Keppy, 1981, Molec. gen. Genet. 181(3): 319--324
        The recombinational analysis of aberrations and the position of the Notch locus on the polytene chromosome of Drosophila. [FBrf0037065]
        Welshons, 1974, Genetics 76: 775--794
        The cytogenetic analysis of a fractured gene in Drosophila. [FBrf0026367]
        Green, 1967, Genetics 56: 467--482
        The genetics of a mutable gene at the white locus of Drosophila melanogaster. [FBrf0018632]
        FlyBase analysis
        FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type.
        En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]
        Book
        Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster.
        The Genome of Drosophila melanogaster. [FBrf0066905]