FB2025_01 , released February 20, 2025
Aberration: Dmel\Df(1)N12
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General Information
Symbol
Df(1)N12
Species
D. melanogaster
Name
FlyBase ID
FBab0000595
Feature type
chromosomal_deletion
Computed Breakpoints include

11D1-11D2;11F1-11F2

Features within 11D1--11F2
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
X ray
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Cook et al., 1997, Duffy et al., 1996, Harbecke and Lengyel, 1995, Pauli et al., 1995, Anand and Chandra, 1994, Watson et al., 1991, Deak et al., 1982, Craymer and Roy, 1980, Lefevre and Peterson, 1972)
Breakpoints

11D1-11D2;11F1-11F2

(Cook et al., 1997, Duffy et al., 1996, Harbecke and Lengyel, 1995, Pauli et al., 1995, Watson et al., 1991, Deak et al., 1982, Craymer and Roy, 1980, Lefevre and Peterson, 1972)

11D1-11D2;11F7-11F8

(Anand and Chandra, 1994)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

bk1 << hep << mew << bk2 << s

Genetic mapping information
Comments

This deletion removes multiple ribosomal protein-coding genes (in addition to other genes).

(Marygold et al., 2007)
Comments on Cytology

Left limit of break 1 from polytene analysis (FBrf0023568) Right limit of break 1 from inclusion of hep (FBrf0083963) Limits of break 2 from polytene analysis (FBrf0023568)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
    In these cases, there will be no "Export to Hitlist" button to the left.
    Phenotypic Data
    In combination with other aberrations

    Transmission rate of Dp(1;f)J21A through females to progeny is 28%, Df(1)N12 has no effect on transmission.

    (Cook et al., 1997)
    NOT in combination with other aberrations

    Flies heterozygous for the deletion show a Minute bristle phenotype.

    (Marygold et al., 2007)

    Does not cause unconditional lethality in hybrid females when heterozygous with D.simulans chromosome.

    (Coyne et al., 1998)

    No second site non-complementing phenotype with zipEbr and zipmhc-c6.1.

    (Halsell and Kiehart, 1998)

    Shows no maternal enhancement of dpphr4.

    (Nicholls and Gelbart, 1998)

    Dominantly causes tergite defects in less than 50% of run3 heterozygotes.

    (Duffy et al., 1996)

    Deficient embryos show an uninterpretable mutant midgut phenotype.

    (Bilder and Scott, 1995)

    Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovoD2.

    (Pauli et al., 1995)

    No significant change in female lethality when in combination with Sxlf1.

    (Anand and Chandra, 1994)

    Hemizygous embryos were examined with polarised light microscopy and antibody staining: muscle pattern incomplete due to muscle absences and detachments.

    (Drysdale et al., 1993)
    Stocks (2)
    Notes on Origin
    Discoverer

    Lefevre.

     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (3)
    Reported As
    Symbol Synonym
    Df(1)N12
    (Degennaro et al., 2011, Crest et al., 2007, Folkers et al., 2006, Möller et al., 2005, Savvateeva-Popova et al., 2004)
    Df(1)sno-N12
    N12
    (Sanchez et al., 1994)
    Name Synonyms
    Secondary FlyBase IDs
      References (39)