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General Information
Symbol
Df(1)RA2
Species
D. melanogaster
Name
FlyBase ID
FBab0000663
Feature type
Computed Breakpoints include

7D18-7D22;8A4

Deleted Segment
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
Class of aberration (relative to wild type)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

l(1)ESHS36 << bk1 << eggroll << l(1)7Do << bk2 << rdgA

Genetic mapping information
Comments

Breakpoint(s) molecularly mapped

Comments on Cytology

Left limit of break 1 from polytene analysis (FBrf0058587) Right limit of break 1 from inclusion of l(1)7Dm (FBrf0105246) Left limit of break 2 from polytene analysis (FBrf0034402) Right limit of break 2 from polytene analysis (FBrf0099402)

Sequence Crossreferences
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Phenotypic Data
In combination with other aberrations

The viability of Df(1)svr/Df(1)RA2 or Df(1)svr/+ female progeny derived from a cross between Df(1)RA2/+ females and Df(1)svr/Y males is severely reduced. The viability of Df(1)N71/Df(1)RA2 or Df(1)N71/+ female progeny derived from a cross between Df(1)RA2/+ females and Df(1)N71/Y males is severely reduced.

Fails to complement Df(1)D46.

Df(1)RA2/Ubl females slight oc phenotype

NOT in combination with other aberrations

Does not cause unconditional lethality in hybrid females when heterozygous with D.simulans chromosome.

Intermediate second site non-complementing phenotype with zipEbr and zipmhc-c6.1 : malformed phenotype penetrance 25-75%.

Shows no maternal enhancement of dpphr4.

Dominantly causes tergite defects in less than 50% of run3 heterozygotes.

Deficient embryos show an uninterpretable mutant midgut phenotype.

Homozygous embryos are very abnormal compared to wild-type.

Heterozygosity for this deletion enhances the mutant ovarian phenotype of ovoD2.

More than six-fold reduction in sex ratio and significant levels of female lethality is observed when in combination with Sxlf1. Female lethality is also reduced when in combination with da1 but restored when in combination with emcML.

The viability of Sxlf1/Df(1)RA2 female progeny derived from a cross between Df(1)RA2/+ females and Sxlf1/Y males is severely reduced. Viability is recovered if the Sxlf1/Df(1)RA2 female progeny also carry Dp(1;3)sn13a1 or if the Df(1)RA2/+ mothers also carry Dp(1;3)sn13a1.

Heterozygotes have ocelli placed far back on the head and there is a slight indentation in the cuticle beneath the postvertical bristles.

Stocks (2)
Notes on Origin
Discoverer

Lefevre.

 
Balancer / Genotype Variants of the Aberration
 
Separable Components
 
Other Comments
 

"7D18--22;8A4--5" was stated as revision. Complements Df(1)Desi-S3.

Synonyms and Secondary IDs (8)
References (63)