Aberration Dmel\Df(1)bb158

General Information
Symbol	Dmel\Df(1)bb158	Species	D. melanogaster
Name	Deficiency (1) bobbed	FlyBase ID	FBab0000749
Feature type	chromosomal_deletion
Also Known As	Df(1)bb^1-158, bb^l-158

Computed Breakpoints include	[20F--h32];[>h26]
Deleted segment	20F--h26
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor
Mutagen	X ray (Lindsley et al., 1960)
Class of aberration (relative to progenitor)	chromosomal_deletion
Breakpoints
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	su(f) << bk1 << bb << bk2
Genetic mapping information
Comments
Comments on Cytology
	Left limit of break 1 from non-inclusion of su(f) (FBrf0036523) Right limit of break 1 from inclusion of bb (FBrf0013319) Left limit of break 2 from inclusion of bb (FBrf0013319)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	bb (Lindsley et al., 1960, Rahman and Lindsley, 1980, Rahman and Lindsley, 1981) Zhr (Sawamura and Yamamoto, 1993)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	fur (Blake et al., 1991) su(f) (Rahman and Lindsley, 1981)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations	Male sterile in combination with T(Y;2)b10, T(Y;2)t22, T(Y;2)L141, T(Y;2)b13, T(Y;2)a2 or T(Y;2)c5. (Lyttle, 1984) Fertile when in combination with Dp(1;Y)B^SYy⁺ or Dp(1;Y)y⁺mal¹²⁶ and weakly fertile when in combination with Dp(1;Y)mal⁺. (Rahman and Lindsley, 1981) Heterozygotes with Dp(1;Y)y⁺mal⁺ are sterile. Fertility is higher in combination with Dp(1;Y)y⁺mal¹²⁶. (Rahman and Lindsley, 1980) Df(1)bb158/Dp(1;f)18 males are bb⁺, show eo phenotype in 50% of the flies (Schalet) Df(1)bb158/Dp(1;f)122 males are bb⁺, show eo phenotype in 50% of the flies (Schalet) Df(1)bb158/Df(1)mal³ females are bb⁺, show eo phenotype in 50% of the flies (Schalet) Df(1)bb158/Df(1)17-137 females are bb, show eo phenotype in >50% of flies (Schalet)
NOT in combination with other aberrations	X/0 males are lethal (relative viability of 0), X/Y males are viable (relative viability of 1.13). Levels of maternal nondisjunction are low. (Lindsley et al., 1960) X0 male lethal. Segregates irregularly from the Y chromosome. Male sterile or nearly so in combination with T(Y;A)'s (Lindsley, Pearson, Rokop, Jones and Stern, 1979, Genetics 91: s69-70) or with Dp(1;Y)y⁺mal⁺ (Rahman and Lindsley, 1981).
Stocks ( 2 )
Bloomington	3143 Df(1)bb158, y¹/Dp(1;Y)y⁺/C(1)*; ca¹ awd^K
Kyoto	106876 Df(1)bb158, y¹/Dp(1;Y)y⁺/C(1)*; ca¹ awd^K
Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments
	Exhibit Zhr phenotype and produce viable hybrid females from a cross between D.melanogaster males and D.sechellia females. Paternal non-disjunction produced viable X0 hybrid males at a low frequency. (Sawamura and Yamamoto, 1993)
Synonyms & Secondary IDs ( 7 )
Reported As
Symbol Synonym	bb^1-158 (Blake et al., 1991) bb^l-158 (Rahman and Lindsley, 1981, Lyttle, 1984) Df(1)bb158 Df(1)bb^1-158 (Rahman and Lindsley, 1980, Clark and Lyckegaard, 1990) Df(1)bb¹⁵⁸ (Subramanian and Bickel, 2009) Df(1)bb^l-
Name Synonym	Deficiency (1) bobbed
Secondary FlyBase IDs

References ( 15 )
Research paper	Subramanian and Bickel, 2009, Genetics 181(4): 1207--1218 Heterochromatin-mediated association of achiasmate homologs declines with age when cohesion is compromised. [FBrf0207808] Robbins, 1999, Genetics 151(1): 251--262 Are unpaired chromosomes spermicidal? A maximum-likelihood analysis of segregation and meiotic drive in Drosophila melanogaster males deficient for the ribosomal DNA. [FBrf0107168] Sawamura and Yamamoto, 1993, Mol. Gen. Genet. 239(3): 441--449 Cytogenetical localization of Zygotic hybrid rescue (Zhr), a Drosophila melanogaster gene that rescues interspecific hybrids from embryonic lethality. [FBrf0059084] Blake et al., 1991, J. Neurogenet. 7: 213--228 Fused rhabdomeres (fur) in Drosophila: an eye mutation that alters rhabdomere morphology and retinal function. [FBrf0054501] Clark and Lyckegaard, 1990, Evolution 44(8): 2106--2112 Two neutrality tests of Y-linked R DNA variation in Drosophila melanogaster. [FBrf0051732] Williams et al., 1990, Proc. Natl. Acad. Sci. U.S.A. 87: 3156--3160 Superstructure of the Drosophila ribosomal gene family. [FBrf0052835] Williams et al., 1989, Genetics 122(3): 617--624 Reciprocal recombination and the evolution of the ribosomal gene family of Drosophila melanogaster. [FBrf0049917] Lyttle, 1984, Genetics 106: 423--434 Chromosomal control of fertility in Drosophila melanogaster. [FBrf0040952] Rahman and Lindsley, 1981, Genetics 99(1): 49--64 Male-sterilizing interactions between duplications and deficiencies for proximal X-chromosome material in Drosophila melanogaster. [FBrf0036523] Rahman and Lindsley, 1980, D. I. S. 55: 123--124 Effect of proximal X-chromosome deletions on male fertility. [FBrf0034331] Yamamoto and Miklos, 1978, Chromosoma 66: 71--98 Genetic studies on heterochromatin in Drosophila melanogaster and their implications for the functions of satellite DNA. [FBrf0031205] Lindsley et al., 1960, Genetics 45(12): 1649--1670 Sex-linked recessive lethals in Drosophila whose expression is suppressed by the Y chromosome. [FBrf0013319]
Abstract	Lindsley et al., 1979, Genetics 91: s69--s70 Genotypic features causing sterility of males carrying a bobbed-deficient X chromosome. [FBrf0033294]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]
Book	Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster. The Genome of Drosophila melanogaster. [FBrf0066905]