Aberration Dmel\Df(1)bi-D2

General Information
Symbol	Dmel\Df(1)bi-D2	Species	D. melanogaster
Name	Deficiency (1) bifid	FlyBase ID	FBab0000756
Feature type	chromosomal_deletion
Also Known As	Df(1)bi^D2

Computed Breakpoints include	4B6;4E1
Deleted segment	4B6--4E1
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Aberration
Cytological Order
Progenitor	T(1;2)bi^D2 (Oliver et al., 1988)
Mutagen	gamma ray (Garfinkel et al., 1992) X ray (Banga et al., 1986)
Class of aberration (relative to progenitor)	chromosomal_deletion (Garfinkel et al., 1992, Oliver et al., 1988, Pauli et al., 1995, Landecker et al., 1994)
Breakpoints	4B6-4C1;4D7-4E1 (Garfinkel et al., 1992, Landecker et al., 1994, Pauli et al., 1995) 4B6;4D7-4E1 (Oliver et al., 1988)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	norpA << bk1 << lac << ovo << bk2 << rg
Genetic mapping information
Comments	Breakpoint(s) molecularly mapped (Garfinkel et al., 1992)
Comments on Cytology
	Limits of break 1 from polytene analysis (FBrf0048195) Left limit of break 2 from inclusion of ovo (FBrf0048195) Right limit of break 2 from polytene analysis (FBrf0048195)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	amb (Banga et al., 1986, Oliver et al., 1988) bi (Banga et al., 1986, Oliver et al., 1988) ctp (Ghosh-Roy et al., 2004) lac (Banga et al., 1986, Oliver et al., 1988) ovo (Oliver et al., 1988, Garfinkel et al., 1992, Mevel-Ninio et al., 1995) peb (Oliver et al., 1988, Mevel-Ninio et al., 1995) rb (Banga et al., 1986, Oliver et al., 1988)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	brn (Oliver et al., 1988) c (Oliver et al., 1988) cho (Oliver et al., 1988) ec (Oliver et al., 1988) fs(1)A456 (Oliver et al., 1988) fs(1)A1059 (Oliver et al., 1988) mei-9 (Banga et al., 1986, Oliver et al., 1988) norpA (Banga et al., 1986, Oliver et al., 1988) ovo (Oliver et al., 1987, Mevel-Ninio et al., 1991) rg (Oliver et al., 1988) snf (Oliver et al., 1988) spoon (Hadad et al., 2011)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovo^D2. (Pauli et al., 1995) Hemizygous embryos were examined with polarised light microscopy and antibody staining: muscle pattern grossly deranged. (Drysdale et al., 1993)
Stocks ( 2 )
Bloomington	3203 Df(1)bi-D2, w^*/FM7c
Kyoto	106915 Df(1)bi-D2, w^*/FM7c
Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments
	Removes the svb but not ovo function (Mevel-Ninio et al., 1995)
Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	Df(1)bi^D2 (Delon et al., 2003, Garfinkel et al., 1994, Mevel-Ninio et al., 1995, Mevel-Ninio et al., 1991, Banga et al., 1986, Oliver et al., 1988, Garfinkel et al., 1992) Df(1)biD2 (Pauli et al., 1995) Df(1)bi-D2 (Hadad et al., 2011, Silies and Klämbt, 2010)
Name Synonym	Deficiency (1) bifid
Secondary FlyBase IDs

References ( 17 )
Research paper	Hadad et al., 2011, Mech. Dev. 128(7-10): 471--482 Drosophila spoonbill encodes a dual-specificity A-kinase anchor protein essential for oogenesis. [FBrf0216765] Silies and Klämbt, 2010, Nat. Neurosci. 13(11): 1357--1364 APC/C(Fzr/Cdh1)-dependent regulation of cell adhesion controls glial migration in the Drosophila PNS. [FBrf0212144] Ghosh-Roy et al., 2004, Mol. Biol. Cell 15(5): 2470--2483 Cytoplasmic Dynein-dynactin complex is required for spermatid growth but not axoneme assembly in Drosophila. [FBrf0174932] Delon et al., 2003, Mech. Dev. 120(7): 747--758 The Ovo/Shavenbaby transcription factor specifies actin remodelling during epidermal differentiation in Drosophila. [FBrf0162225] Mevel-Ninio et al., 1995, Mech. Dev. 49(1-2): 83--95 ovo, a Drosophila gene required for ovarian development, is specifically expressed in the germline and shares most of its coding sequences with shavenbaby, a gene involved in embryo patterning. [FBrf0080251] Pauli et al., 1995, Genetics 139(2): 713--732 Identification of regions interacting with ovo^D mutations: Potential new genes involved in germline sex determination or differentiation in Drosophila melanogaster. [FBrf0080317] Pauli et al., 1995, D. I. S. 76: 107--124 Dose dependent enhancers and suppressors of ovoD2. [FBrf0082455] Garfinkel et al., 1994, Mol. Cell. Biol. 14(10): 6809--6818 Multiple products from the shavenbaby-ovo gene region of Drosophila melanogaster: Relationship to genetic complexity. [FBrf0076971] Landecker et al., 1994, Dev. Genet. 15(5): 425--434 Screen for enhancers of Polycomb and Polycomblike in Drosophila melanogaster. [FBrf0076124] Drysdale et al., 1993, Rouxs Arch. Dev. Biol. 202(5): 276--295 Genes required for embryonic muscle development in Drosophila melanogaster: A survey of the X chromosome. [FBrf0059320] Garfinkel et al., 1992, Genetics 130(4): 791--803 Molecular genetics of the Drosophila melanogaster ovo locus, a gene required for sex determination of germline cells. [FBrf0056260] Mevel-Ninio et al., 1991, EMBO J. 10: 2259--2266 The ovo gene of Drosophila encodes a zinc finger protein required for female germ line development. [FBrf0053878] Oliver et al., 1988, Genetics 120: 159--171 Genetic evidence that the sans fille locus is involved in Drosophila sex determination. [FBrf0048195] Oliver et al., 1987, Genes Dev. 1: 913--923 The ovo locus is required for sex-specific germ line maintenance in Drosophila. [FBrf0046291] Banga et al., 1986, Chromosoma 93: 341--346 Cytogenetic characterization of the 4BC region on the X chromosome of Drosophila melanogaster: localization of the mei-9, norpA and omb genes. [FBrf0043953]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]
Book	Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster. The Genome of Drosophila melanogaster. [FBrf0066905]