FlyBase Aberration Report: Dmel\Df(1)ct4b1

General Information

Symbol

Df(1)ct4b1

Species

D. melanogaster

Name

FlyBase ID

FBab0000798

Feature type

chromosomal_deletion

Also Known As

Df(1)ct^4b1

Computed Breakpoints include

7B2;7C4

Features within 7B2--7C4

Sequence coordinates

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

Progenitor

Mutagen

X ray

(Johnson and Judd, 1979, Lefevre and Johnson, 1973)

Class of aberration (relative to wild type)

chromosomal_deletion

(FlyBase, 2007)

Class of aberration (relative to progenitor)

chromosomal_deletion

(Harbecke and Lengyel, 1995, Pauli et al., 1995, Watson et al., 1991, Brown et al., 1988, Johnson and Judd, 1979, Lefevre and Johnson, 1973)

Breakpoints

7B3;7C4

(Johnson and Judd, 1979, Lefevre and Johnson, 1973)

7B2-7B4;7C2-7C4

(Brown et al., 1988)

7B2;7C4

(Watson et al., 1991)

7B2-7B4;7C3-7C4

(Harbecke and Lengyel, 1995, Pauli et al., 1995)

Causes alleles

dec^ct4b1

(Nogueron et al., 2000)

Carries alleles

Transposon Insertions

Formalized genetic data

l(1)ESHS31 << bk1 << l(1)47 << dec-1 << bk2 << l(1)ESHS35

Genetic mapping information

Comments

Breakpoint(s) molecularly mapped

(Stewart and Denell, 1993, Jack et al., 1991)

Proximal breakpoint lies between coordinates 3.6 and 4.0 on the molecular map of dec-1.

Comments on Cytology

Left limit of break 1 from polytene analysis (FBrf0048669) Right limit of break 1 from polytene analysis (FBrf0053739) Limits of break 2 from polytene analysis (FBrf0025084)

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

Partially deleted / disrupted

Molecular Data

Completely deleted

Partially deleted

Genes NOT Deleted / Disrupted

Complementation Data

fs(1)h

(Eeken et al., 1985)

l(1)7Do

(Eeken et al., 1985)

l(1)7Fg

(Eeken et al., 1985)

(Eeken, 1982)

(Eeken, 1982)

(Eeken, 1982)

(Eeken, 1982)

(Eeken, 1982)

(Eeken, 1982)

(Eeken, 1982)

(Eeken, 1982)

(Eeken, 1982)

(Eeken, 1982)

(Eeken, 1982)

(Eeken, 1982)

(Eeken, 1982)

(Eeken, 1982)

(Eeken, 1982)

(Eeken et al., 1985)

l(1)ESHS25

(Eeken et al., 1985)

l(1)ESHS26

(Eeken et al., 1985)

l(1)ESHS27

(Eeken et al., 1985)

l(1)ESHS28

(Eeken et al., 1985)

l(1)ESHS29

(Eeken et al., 1985)

l(1)ESHS30

(Eeken et al., 1985)

l(1)ESHS31

(Eeken et al., 1985)

l(1)ESHS32

(Eeken et al., 1985)

l(1)ESHS34

(Eeken et al., 1985)

l(1)ESHS35

(Eeken et al., 1985)

l(1)ESHS36

(Eeken et al., 1985)

l(1)ESHS37

(Eeken et al., 1985)

l(1)ESHS38

(Eeken et al., 1985)

l(1)ESHS39

(Eeken et al., 1985)

(Loppin et al., 2001)

sesB

(Rikhy et al., 2003)

(Andersson and Lambertsson, 1990, Eeken et al., 1985)

Molecular Data

Genes Duplicated

Complementation Data

Completely duplicated

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Affected Genes Inferred by Location (0)

If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
In these cases, there will be no "Export to Hitlist" button to the left.

Related Comments

Phenotypic Data

In combination with other aberrations

Df(1)R19/Df(1)ct4b1 females have good viability, about 20% have a kinked femur-like phenotype.

(Johnson and Judd, 1979)

Df(1)ct4b1/Dp(1;3)sn^13a1 viable (Lefevre and Johnson, 1973, Genetics 74:633-45 ).

NOT in combination with other aberrations

Does not cause unconditional lethality in hybrid females when heterozygous with D.simulans chromosome.

(Coyne et al., 1998)

Weak second site non-complementing phenotype with zip^Ebr and zip^mhc-c6.1 : malformed phenotype penetrance 10-24%.

(Halsell and Kiehart, 1998)

Shows no maternal enhancement of dpp^hr4.

(Nicholls and Gelbart, 1998)

Midgut development of mutant embryos is wild type.

(Bilder and Scott, 1995)

Salivary ducts are absent in homozygous embryos. Malpighian tubule material is not elongated.

(Harbecke and Lengyel, 1995)

Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovo^D2.

(Pauli et al., 1995)

Embryos hemizygous for Df(1)ct-J4 and Df(1)ct4b1 were examined with polarised light microscopy and antibody staining: muscle pattern incomplete due to muscle absences.

(Drysdale et al., 1993)

Homozygous embryos lack Malpighian tubules and the gut wall is 3--4 fold thicker than wild type at the junction of the posterior and anterior midgut.

(Liu et al., 1991)

Lethal.

(Johnson and Judd, 1979)

Homozygous lethal.

(Lefevre and Johnson, 1973)

Stocks (4)

3221

106927

108712

Df(1)ct4b1, Dp(1;1)sn^S93/FM7c

106918

Df(1)ct4b1, oc¹ ptg¹; Dp(1;3)ct^J8/Ubx^*; C(1)DX, y¹

Notes on Origin

Discoverer

Hannah, 1947.

(Lefevre and Johnson, 1973)

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms and Secondary IDs (7)

Reported As

Symbol Synonym

3221

(Rikhy et al., 2003)

Df(1)ct4b1

(Ribot et al., 2022, Ibar and Glavic, 2017, Bonnefoy et al., 2007, Crest et al., 2007, Chen et al., 2006)

Df(1)ct^4b-1

(Lammel and Saumweber, 2000)

Df(1)ct^4b1

(Mauzy-Melitz and Waring, 2003, Jazwinska et al., 1999, Stewart and Denell, 1993, Liu et al., 1991, Watson et al., 1991, Waring et al., 1990, Homyk and Pye, 1989, Perrimon et al., 1989, Brown et al., 1988, Hawley and Waring, 1988, Schalet, 1986, Eeken et al., 1985, Eeken, 1982, Johnson and Judd, 1979, Lefevre and Johnson, 1973)

Df(1)ct^4bl

(Homyk and Emerson, 1988)

ct4b1

(Yamaguchi et al., 2001)

ct^4b1

(Sanchez et al., 1994)

Name Synonyms

Secondary FlyBase IDs

References (48)

Report Sections

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