FlyBase Aberration Report: Dmel\Df(1)hl-a

FB2025_01 , released February 20, 2025

FB2025_01 , released February 20, 2025

Aberration: Dmel\Df(1)hl-a

General Information

Symbol

Df(1)hl-a

Species

D. melanogaster

Name

FlyBase ID

FBab0000832

Feature type

chromosomal_deletion

Also Known As

Df(1)hl^a

Computed Breakpoints include

7B7;7E2

Features within 7B7--7E2

Genomic Maps

Sequence coordinates

X:7,678,859..7,901,331 (Df(1)hl-a:bk1)

(Cook, 2016.2.8)

X:8,276,200..8,409,272 (Df(1)hl-a:bk2)

(Cook, 2016.2.8)

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

Progenitor

Mutagen

Class of aberration (relative to wild type)

chromosomal_deletion

(FlyBase, 2007)

Class of aberration (relative to progenitor)

chromosomal_deletion

(Porsch et al., 1998)

Breakpoints

7B7;7E2

(Porsch et al., 1998)

Causes alleles

Carries alleles

Transposon Insertions

Formalized genetic data

ct << bk1 << M(1)7C << bk2 << ptg

Genetic mapping information

Comments

The X:7678859..7901331 release 6 coordinates of the left breakpoint are estimates. The left extent corresponds to the right end of ct, which published results say is not deleted. The right extent corresponds to the right end of RpS6, which published results say is deleted.

(Cook, 2016.2.8)

The X:8276200..8409272 release 6 coordinates of the right breakpoint are estimates. The left extent corresponds to the right end of nAChRalpha3. The right extent corresponds to the left end of Trf2. FBrf0144880 mapped the breakpoint to this region.

(Cook, 2016.2.8)

This deletion removes multiple ribosomal protein-coding genes (in addition to other genes).

(Marygold et al., 2007)

Comments on Cytology

All limits from polytene analysis (FBrf0103013)

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

(Zheng et al., 2003)

(Zheng et al., 2003, Henderson and Andrew, 1998)

(Henderson and Andrew, 1998)

(Zheng et al., 2003, Henderson and Andrew, 1998)

(Zheng et al., 2003, Henderson and Andrew, 1998)

(Zheng et al., 2003, Henderson and Andrew, 1998)

(Zheng et al., 2003, Henderson and Andrew, 1998)

(Zheng et al., 2003)

(Zheng et al., 2003, Henderson and Andrew, 1998)

(Zheng et al., 2003, Henderson and Andrew, 1998)

(Zheng et al., 2003, Henderson and Andrew, 1998)

(Zheng et al., 2003, Henderson and Andrew, 1998)

(Zheng et al., 2003, Henderson and Andrew, 1998)

(Zheng et al., 2003, Henderson and Andrew, 1998)

(Zheng et al., 2003, Henderson and Andrew, 1998)

(Andersson and Lambertsson, 1990)

(Andersson and Lambertsson, 1990)

(Andersson and Lambertsson, 1990)

(Stronach and Perrimon, 2002, Stronach, 1999.3.4)

(Zheng et al., 2003)

(Zheng et al., 2003, Henderson and Andrew, 1998, Andersson and Lambertsson, 1990)

Partially deleted / disrupted

Molecular Data

Completely deleted

(Marygold et al., 2007)

(Marygold et al., 2007)

(Marygold et al., 2007)

Partially deleted

Genes NOT Deleted / Disrupted

Complementation Data

(Andersson and Lambertsson, 1990)

(Andersson and Lambertsson, 1990)

Molecular Data

Genes Duplicated

Complementation Data

Completely duplicated

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Affected Genes Inferred by Location (105)

Related Comments

Phenotypic Data

In combination with other aberrations

NOT in combination with other aberrations

Flies heterozygous for the deletion show a Minute bristle phenotype.

(Marygold et al., 2007)

Deficiency heterozygotes demonstrated extremely retarded development during the larval period.

(Andersson and Lambertsson, 1990)

Stocks (1)

6698

Df(1)hl-a, w¹ cv¹ Bar¹/C(1)DX, y¹ f¹; Dp(1;2)sn⁺72d/Dp(?;2)bw^D, bw^D

Notes on Origin

Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Df(1)hl-a

(Casas-Tintó and Ferrús, 2021, Li et al., 2020, Sawyer et al., 2020, Rimal et al., 2019)

Df(1)hl^a

(Porsch et al., 1998, Andersson and Lambertsson, 1990)

Ir7a(Df)

(Rimal et al., 2019)

Name Synonyms

Secondary FlyBase IDs

References (13)

Report Sections