Aberration Dmel\Df(1)m259-4

General Information
Symbol	Dmel\Df(1)m259-4	Species	D. melanogaster
Name	Deficiency (1) miniature	FlyBase ID	FBab0000846
Feature type	chromosomal_deletion
Also Known As	Df(1)m^259-4, Df m^259-4, m^259-4, Df(1)m^259.4

Computed Breakpoints include	10C2;10E2
Deleted segment	10C2--10E2
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor
Mutagen	X ray
Class of aberration (relative to progenitor)	chromosomal_deletion (Geer et al., 1983, Prudhommeau and Proust, 1990, Voelker et al., 1985, Wilson and Fabian, 1986, Pauli et al., 1995, Lim, 1979, Duffy et al., 1996, Arora et al., 1987, Konopka et al., 1991, Rodrigues et al., 1991, Wilson, 1996, Simmons et al., 1984, Ashok et al., 1998, DiBartolomeis et al., 2002)
Breakpoints	10C1-10C2;10E1-10E2 (Simmons et al., 1984) 10C2-10C3;10E1-10E2 (Konopka et al., 1991, Rodrigues et al., 1991, Pauli et al., 1995, Duffy et al., 1996, Wilson, 1996, DiBartolomeis et al., 2002) 10C2-10C3;10E2-10E3 (Lim, 1979, Geer et al., 1983, Voelker et al., 1985, Prudhommeau and Proust, 1990) 10C2;10D4 (Ashok et al., 1998) 10C2;10E2 (Wilson and Fabian, 1986) 10C12;10E3 (Arora et al., 1987)
Causes alleles	m^259-4 (Burdick, 1961, Roch et al., 2003)
Carries alleles
Transposon Insertions
Formalized genetic data	l(1)10Bj << bk1 << RpII215 << l(1)10Db << bk2 << gustD
Genetic mapping information
Comments	Breakpoint(s) molecularly mapped (Jackson, 1990) Left DNA breakpoint between -19 and -23 kb (Woods and Marsh).
Comments on Cytology
	Ref: FBrf0034402. (Wilson and Fabian, 1986) Left limit of break 1 from polytene analysis (FBrf0033204) Right limit of break 1 from inclusion of RpII215 (FBrf0038443) Left limit of break 2 from polytene analysis (FBrf0033204) Right limit of break 2 from polytene analysis (FBrf0040956)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	dsl (Voelker et al., 1985) gustB (Arora et al., 1987) gustC (Rodrigues et al., 1991) l(1)10Cc (Voelker et al., 1985, Eeken et al., 1985) l(1)10Cd (Voelker et al., 1985) l(1)10Ce (Kramers et al., 1983, Voelker et al., 1985) l(1)10Db (Voelker et al., 1985) l(1)10Dc (Voelker et al., 1985) m (Roch et al., 2003, Lefevre, 1969, Kramers et al., 1983, Eeken et al., 1985) Met (Ashok et al., 1998, Wilson and Fabian, 1986, Minkoff and Wilson, 1992) nod (Voelker et al., 1985) RpII215 (Mortin and Kaufman, 1982, Voelker et al., 1985, Eeken et al., 1985) tyl (Craymer and Roy, 1980)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	dy (DiBartolomeis et al., 2002, Roch et al., 2003, Newby et al., 1991, Konopka et al., 1991) Gtd (Rodrigues et al., 1991) gustD (Rodrigues et al., 1991) hop (Eeken et al., 1985, Hanratty and Dearolf, 1993) l(1)10Ae (Eeken et al., 1985) l(1)10Bj (Voelker et al., 1985) l(1)10Bk (Voelker et al., 1985) l(1)10Bl (Voelker et al., 1985) l(1)10Bm (Kramers et al., 1983) l(1)10Bp (Schalet, 1986) l(1)10Bq (Kramers et al., 1983) l(1)10Br (Kramers et al., 1983) l(1)10Bs (Kramers et al., 1983) l(1)10Bt (Kramers et al., 1983) l(1)B8.5 (Proust et al., 1992) l(1)B64.2 (Proust et al., 1992) l(1)D36.5 (Proust et al., 1992) l(1)ESHS40 (Eeken et al., 1985) l(1)ESHS41 (Eeken et al., 1985) l(1)ESHS42 (Eeken et al., 1985) l(1)ESHS43 (Eeken et al., 1985) l(1)ESHS44 (Eeken et al., 1985) l(1)J30.4 (Proust et al., 1992) m (DiBartolomeis et al., 2002) ras (Eeken et al., 1985) roX2 (Franke and Baker, 1999) rtv (Eeken et al., 1985) sbr (Eeken et al., 1985) v (Eeken et al., 1985) wisp (Tadros et al., 2003)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations	Df(1)KA6/Df(1)m259-4 heterozygotes are viable. (Rodrigues et al., 1991) Heterozygotes with Df(1)KA6 survive and have an extreme m phenotype with flimsy wings. (Craymer and Roy, 1980) Df(1)m259-4/Df(1)KA6 viable (Craymer and Roy, 1980). Df(1)m259-4/Df(1)KA6 extreme m phenotype (Craymer and Roy, 1980)
NOT in combination with other aberrations	hemizygous late embryonic lethal (Franke and Baker, 1999) Dominantly causes tergite defects in less than 50% of run³ heterozygotes. (Duffy et al., 1996) Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovo^D2. (Pauli et al., 1995) male lethal. Heterozygote with m has m phenotype. Heterozygote with dy is wild type. Recombines with m⁵⁹, m,
Stocks ( 4 )
Bloomington	905 Df(1)m259-4, ras¹ m^259-4 f¹/Dp(1;Y)y⁺v⁺#3/C(1)DX, y¹ w¹ f¹
Kyoto	106048 Df(1)m259-4, m^259-4/FM4 100969 Dp(1;Y)y⁺v⁺#3 / Df(1)m259-4, feo¹ v¹ / FM6 106112 Df(1)m259-4, ras¹ m^259-4 f¹/Dp(1;Y)y⁺v⁺#3/C(1)DX, y¹ w¹ f¹
Notes on Origin
Discoverer	Demerec, Sep. 1933.

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 12 )
Reported As
Symbol Synonym	Df(1)259-4 (Burdick, 1961) Df(1)M259-4 (Franke and Baker, 1999) Df(1)m259-4 (Zhao et al., 2008) Df(1)m259.4 (Prudhommeau and Proust, 1990) Df(1)m^259-4 (Lammel and Saumweber, 2000, Wilson and Ashok, 1998, Ashok et al., 1998, Simmons et al., 1984, Mortin and Kaufman, 1982, Rodrigues et al., 1991, Konopka et al., 1991, Craymer and Roy, 1980, Minkoff and Wilson, 1992, Lim, 1979, Wilson and Fabian, 1986, Eeken et al., 1985, Newby et al., 1991, Kulkarni and Hall, 1987) Df(1)M^259-4 (Bahri and Chia, 1994) Df(1)m^259.4 (Wieschaus et al., 1984, Prudhommeau and Proust, 1990) Df(1)m²⁵⁹ (Roch et al., 2003) Df m^259-4 (Lefevre, 1969, Proust et al., 1992) Dfm²⁵⁹ m^259-4 (Sanchez et al., 1994, Geer et al., 1983)
Name Synonym	Deficiency (1) miniature
Secondary FlyBase IDs

References ( 42 )

Generate a list of	All references relating to this aberration ( 42 )

List References by type	Research paper ( 39 ) Personal communication to FlyBase ( 1 ) FlyBase analysis ( 1 ) Book ( 1 )
Recent research papers (0)
	All research papers listed in FlyBase were published before 2011 Show research papers ...