Aberration Dmel\Df(1)ovo7

General Information
Symbol	Dmel\Df(1)ovo7	Species	D. melanogaster
Name	Deficiency (1) ovo	FlyBase ID	FBab0000876
Feature type	chromosomal_deletion
Also Known As	Df(1)ovo^D1rG7, Df(1)ovoG7

Computed Breakpoints include	4C6;4E2-4E3
Deleted segment	4C6--4E3
Map ( GBrowse )	Untitled Document Error No matching regions found.
Sequence coordinates	X:4,421,875..4,425,334 [+] (Df(1)ovo7:bk1) (Pflugfelder et al., 1990, Pflugfelder et al., 1992)
Member of large scale dataset(s)
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor	ovo^D1 (Oliver et al., 1987, Garfinkel et al., 1992)
Mutagen	gamma ray (Oliver et al., 1987, Garfinkel et al., 1992)
Class of aberration (relative to progenitor)	chromosomal_deletion (Pflugfelder et al., 1990, Salz, 1992, Garfinkel et al., 1992)
Breakpoints	4A4;4F1-4F2 (Salz, 1992) 4C5-4C6;4E2-4E3 (Pflugfelder et al., 1990, Garfinkel et al., 1992)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	bi << bk1 << rb << rg << bk2 << snf
Genetic mapping information
Comments	Breakpoint(s) molecularly mapped (Pflugfelder et al., 1990)
Comments on Cytology
	Distal break defines the 3' limit of the olfactory lobe regulatory region. (Brunner et al., 1992) Left limit of break 1 from non-inclusion of bi (FBrf0048195) Right limit of break 1 from inclusion of amb (FBrf0048195) Limits of break 2 from polytene analysis (FBrf0051990)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	amb (Oliver et al., 1988) l(1)4Ea (Salz, 1992) mus108 (Laurencon, 2001.7.21) ovo (Oliver et al., 1988, Salz, 1992, Garfinkel et al., 1992) peb (Oliver et al., 1987, Oliver et al., 1988) rb (Oliver et al., 1988, Pflugfelder et al., 1990) rg (Oliver et al., 1988, Salz, 1992)
Molecular Data
Completely deleted	rap (Sigrist and Lehner, 1997)
Genes NOT Deleted / Disrupted
Complementation Data
	bi (Oliver et al., 1988) brn (Oliver et al., 1988) cho (Oliver et al., 1988) cv (Oliver et al., 1988) ec (Oliver et al., 1988) fs(1)A456 (Oliver et al., 1988, Salz, 1992) fs(1)A1059 (Oliver et al., 1988, Salz, 1992) l(1)4Fa (Salz, 1992) lac (Oliver et al., 1988, Pflugfelder et al., 1990) mei-9 (Oliver et al., 1988) norpA (Pflugfelder et al., 1990, Oliver et al., 1988) snf (Oliver et al., 1988, Salz, 1992)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	Gene activity of ovo is not detectable, embryonic lethal. Female germ line has no egg chambers. (Oliver et al., 1987)
Stocks ( 0 )

Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 6 )
Reported As
Symbol Synonym	Df(1)ovo7 Df(1)ovo^D1rG7 (Kretzschmar et al., 2000, Roth et al., 1991, Poeck et al., 1991, Garfinkel et al., 1992, Brunner et al., 1992, Poeck et al., 1993, Pflugfelder et al., 1992, Oliver et al., 1988, Oliver et al., 1987, Pflugfelder et al., 1990) Df(1)ovo-D1rG7 Df(1)ovoD7 (Hess et al., 1996) Df(1)ovoG7 (Laurencon, 2001.7.21, Salz, 1992)
Name Synonym	Deficiency (1) ovo
Secondary FlyBase IDs

References ( 16 )
Research paper	Kretzschmar et al., 2000, Genetics 155(1): 213--223 Defective pigment granule biogenesis and aberrant behavior caused by mutations in the Drosophila AP-3 adaptin gene ruby. [FBrf0127175] Sigrist and Lehner, 1997, Cell 90(4): 671--681 Drosophila fizzy-related down-regulates mitotic cyclins and is required for cell proliferation arrest and entry into endocycles. [FBrf0098351] Hess et al., 1996, Differentiation 61(2): 103--111 Spatial and temporal expression of 4f-RNP gene in Drosophila melanogaster. [FBrf0091078] Poeck et al., 1993, Mol. Gen. Genet. 238(3): 325--332 Transcript identification in the optomotor-blind locus of Drosophila melanogaster by intragenic recombination mapping and PCR-aided sequence analysis of lethal point mutations. [FBrf0059076] Brunner et al., 1992, J. Neurogenet. 8(1): 43--55 Mutations in the proximal region of the optomotor-blind locus of Drosophila melanogaster reveal a gradient of neuroanatomical and behavioral phenotypes. [FBrf0056569] Garfinkel et al., 1992, Genetics 130(4): 791--803 Molecular genetics of the Drosophila melanogaster ovo locus, a gene required for sex determination of germline cells. [FBrf0056260] Pflugfelder et al., 1992, Proc. Natl. Acad. Sci. U.S.A. 89: 1199--1203 The lethal(1)optomotor-blind gene of Drosophila melanogaster is a major organizer of optic lobe development: isolation and characterization of the gene. [FBrf0057510] Salz, 1992, Genetics 130: 547--554 The genetic analysis of snf: a Drosophila sex determination gene required for activation of Sex-lethal in both the germline and the soma. [FBrf0056236] Pflugfelder et al., 1990, Genetics 126: 91--104 Genetic and molecular characterization of the optomotor-blind gene locus in Drosophila melanogaster. [FBrf0051990] Oliver et al., 1988, Genetics 120: 159--171 Genetic evidence that the sans fille locus is involved in Drosophila sex determination. [FBrf0048195] Oliver et al., 1987, Genes Dev. 1: 913--923 The ovo locus is required for sex-specific germ line maintenance in Drosophila. [FBrf0046291]
Personal communication to FlyBase	Laurencon, 2001.7.21, mus108. mus108. [FBrf0137504]
Abstract	Poeck et al., 1991, J. Neurogenet. 7: 139 Genetic analysis of the optomotor blind gene locus of Drosophila. [FBrf0064240] Roth et al., 1991, J. Neurogenet. 7: 144 Molecular analysis of the optomotor blind gene locus of Drosophila melanogaster. [FBrf0064252]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]
Book	Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster. The Genome of Drosophila melanogaster. [FBrf0066905]

Aberration Dmel\Df(1)ovo7

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