Aberration Dmel\Df(1)run1112

General Information
Symbol	Dmel\Df(1)run1112	Species	D. melanogaster
Name	Deficiency (1) runt	FlyBase ID	FBab0000920
Feature type	chromosomal_deletion
Also Known As	Df(1)run¹¹¹²

Computed Breakpoints include	19D1-19E1;19E6-19E8
Deleted segment	19D1--19E8
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor
Mutagen	ethyl methanesulfonate
Class of aberration (relative to progenitor)	chromosomal_deletion
Breakpoints
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	bk1 << mal << vao << bk2 << unc
Genetic mapping information
Comments
Comments on Cytology
	Left limit of break 1 from polytene analysis (citation unavailable) Right limit of break 1 from inclusion of mal (FBrf0042290) Left limit of break 2 from inclusion of l(1)19Ed (FBrf0042290) Right limit of break 2 from non-inclusion of unc (FBrf0049891)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	l(1)19Ed (Zusman et al., 1985, Perrimon et al., 1989, Torres and Sanchez, 1992) lf (Perrimon et al., 1989, Torres and Sanchez, 1992) mal (Zusman et al., 1985, Perrimon et al., 1989, Torres and Sanchez, 1992) mell (Perrimon et al., 1989, Torres and Sanchez, 1992) Npc1b (Zusman et al., 1985, Torres and Sanchez, 1992, Perrimon et al., 1989) run (Zusman et al., 1985, Perrimon et al., 1989, Torres and Sanchez, 1992) shakB (Zusman et al., 1985, Perrimon et al., 1989, Torres and Sanchez, 1992) vao (Zusman et al., 1985, Perrimon et al., 1989, Torres and Sanchez, 1992)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	bb (Zusman et al., 1985) eo (Zusman et al., 1985, Perrimon et al., 1989) fliI (Perrimon et al., 1989) fog (Zusman et al., 1985, Perrimon et al., 1989) Hlc (Perrimon et al., 1989) intro (Zusman et al., 1985, Perrimon et al., 1989) l(1)19Fb (Perrimon et al., 1989) l(1)20Ca (Perrimon et al., 1989) l(1)20Cb (Zusman et al., 1985, Perrimon et al., 1989) lfl (Perrimon et al., 1989) mst (Perrimon et al., 1989) slgA (Perrimon et al., 1989) sol (Perrimon et al., 1989) soz (Perrimon et al., 1989) sph (Perrimon et al., 1989) stnA (Zusman et al., 1985, Perrimon et al., 1989) stnB (Zusman et al., 1985, Perrimon et al., 1989) su(f) (Perrimon et al., 1989) tuh1 (Perrimon et al., 1989) unc (Perrimon et al., 1989) uncl (Zusman et al., 1985, Perrimon et al., 1989) wap (Zusman et al., 1985, Perrimon et al., 1989)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations	Df(1)run1112 In(2LR)Sco^rv1LTE35B-4^R double heterozygous females have reduced viability at 29^oC. (Sanchez et al., 1994)
NOT in combination with other aberrations	Display lethal phenotype when in combination with Df(1)N71. (Torres and Sanchez, 1992)
Stocks ( 0 )

Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 6 )
Reported As
Symbol Synonym	Df(1)run1112 Df(1)run¹¹¹² (Lammel and Saumweber, 2000, Sanchez et al., 1994, Torres and Sanchez, 1992) Df(1)run^III2 (Zusman et al., 1985) Df(1)runIII2 (Gutjahr et al., 1993) Df(1)runt¹¹¹² (Perrimon et al., 1989)
Name Synonym	Deficiency (1) runt
Secondary FlyBase IDs

References ( 11 )
Research paper	Lammel and Saumweber, 2000, Dev. Genes Evol. 210(11): 525--535 X-linked loci of Drosophila melanogaster causing defects in the morphology of the embryonic salivary glands. [FBrf0134551] Sanchez et al., 1994, Dev. Genet. 15(3): 251--264 Sex determination in Drosophila melanogaster: X-linked genes involved in the initial step of sex-lethal activation. [FBrf0074350] Granadino et al., 1993, Development 118(3): 813--816 Sex determination in the germ line of Drosophila melanogaster: activation of the gene Sex-lethal. [FBrf0058121] Gutjahr et al., 1993, Development 117(2): 609--623 Complex regulation of early paired expression: initial activation by gap genes and pattern modulation by pair-rule genes. [FBrf0058092] Torres and Sanchez, 1992, Genet. Res. (Camb.) 59(3): 189--198 The segmentation gene runt is needed to activate Sex-lethal, a gene that controls sex determination and dosage compensation in Drosophila. [FBrf0056153] Perrimon et al., 1989, Genetics 121: 313--331 Developmental genetics of loci at the base of the X chromosome of Drosophila melanogaster. [FBrf0049891] Gergen, 1987, Genetics 117: 477--485 Dosage compensation in Drosophila: Evidence that daughterless and Sex-lethal control X chromosome activity at the blastoderm stage of embryogenesis. [FBrf0046379] Gergen and Wieschaus, 1986, Cell 45: 289--299 Dosage requirements for runt in the segmentation of Drosophila embryos. [FBrf0043901] Zusman et al., 1985, D. I. S. 61: 217--218 Report of new mutants. [FBrf0042290]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]
Book	Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster. The Genome of Drosophila melanogaster. [FBrf0066905]