Aberration Dmel\Df(1)sc⁸

General Information
Symbol	Dmel\Df(1)sc⁸	Species	D. melanogaster
Name	Deficiency (1) scute-8	FlyBase ID	FBab0000930
Feature type	chromosomal_deletion
Also Known As	Df(1)sc8

Computed Breakpoints include	[<1A8];1B1--3
Deleted segment	1A8--1B3
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor	In(1)sc⁸
Mutagen	spontaneous
Class of aberration (relative to progenitor)	chromosomal_deletion (Garcia-Bellido and Robbins, 1983)
Breakpoints	XLt;1B1 (Garcia-Bellido and Robbins, 1983)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	bk1 << l(1)1Ac << ac << bk2 << sc
Genetic mapping information
Comments
Comments on Cytology
	Right limit of break 1 from inclusion of cin (FBrf0038305) Left limit of break 2 from inclusion of ac (FBrf0038305) Right limit of break 2 from non-inclusion of sc (FBrf0058545)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	sc (Dambly-Chaudiere and Ghysen, 1987)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	ac (Dambly-Chaudiere and Ghysen, 1987) elav (White et al., 1983) l(1)1Bl (White et al., 1983) rey (Sturtevant, 1948) sc (Lai and Mackay, 1993) skpA (Khush et al., 2002) vnd (White et al., 1983)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	homozygous lethal (Garcia-Bellido and Robbins, 1983) Male lethal, dies as late embryo; larva nearly complete (FBrf0005079) but little or no muscular movement (FBrf0021061).
Stocks ( 20 )
Bloomington	769 Df(1)sc⁸, sc⁸ w^a; Dp(1;3)sc^J4, sc^J4 6348 Df(1)sc⁸, w^a/C(1)M3, y²; Dp(1;3)sc^J4, y⁺, jv¹
Kyoto	102078 Df(1)sc⁸, w^a ; Ts(1Lt;4Lt)sc^H / + 106067 Dp(1;f)101/In(1)sc⁸, Df(1)sc⁸, sc⁸ w^a 106069 Dp(1;f)118/In(1)sc⁸, Df(1)sc⁸, sc⁸ w^a 106070 Dp(1;f)107/In(1)sc⁸, Df(1)sc⁸, sc⁸ w^a 101086 Dp(1;f)107 / In(1)sc⁸ Df(1)sc⁸, sc⁸ w^a 101087 Dp(1;f)118 / In(1)sc⁸ Df(1)sc⁸, sc⁸ w^a 106071 Dp(1;f)135, y²/In(1)sc⁸, Df(1)sc⁸, sc⁸ w^a 108745 Df(1)sc⁸, w^a/C(1)M3, y²; Dp(1;3)sc^J4, jv¹ 102063 Df(1)sc⁸, sc⁸ w^a / C(1)M3 ; Dp(1;3)sc^J4, jv¹ 108746 Df(1)sc⁸, w^a/C(1)M3, y²; Dp(1;3)sc^J4, mwh¹ jv¹/TM1
	More stocks available...
Notes on Origin
Discoverer	Noujdin.

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	Df(1)sc8 (Mueller et al., 2005, ) Df(1)Sc8 (Khush et al., 2002) Df(1)sc⁸
Name Synonym	Deficiency (1) scute-8
Secondary FlyBase IDs

References ( 14 )
Research paper	Mueller et al., 2005, Genetics 171(3): 1137--1152 Genetic modifier screens on hairless gain-of function phenotypes reveal genes involved in cell differentiation, cell growth and apoptosis in Drosophila melanogaster. [FBrf0190751] Khush et al., 2002, Curr. Biol. 12(20): 1728--1737 A ubiquitin-proteasome pathway represses the Drosophila immune deficiency signaling cascade. [FBrf0151852] Nguyen et al., 1997, Development 124(17): 3303--3312 The sidekick gene, a member of the immunoglobulin superfamily, is required for pattern formation in the Drosophila eye. [FBrf0098319] Lai and Mackay, 1993, Genet. Res. (Camb.) 61(3): 177--193 Mapping and characterization of P-element-induced mutations at quantitative trait loci in Drosophila melanogaster. [FBrf0058545] Dambly-Chaudiere and Ghysen, 1987, Genes Dev. 1(3): 297--306 Independent subpatterns of sense organs require independent genes of the achaete-scute complex in Drosophila larvae. [FBrf0046281] Garcia-Bellido and Robbins, 1983, Genetics 103: 235--247 Viability of female germ-line cells homozygous for zygotic lethals in Drosophila melanogaster. [FBrf0039441] White et al., 1983, Genetics 104: 433--448 Genetic and developmental analysis of the locus vnd in Drosophila melanogaster. [FBrf0039456] Baker, 1973, Dev. Biol. 33(2): 429--440 The maternal and zygotic control of development by cinnamon, a new mutant in Drosophila melanogaster. [FBrf0024902] Sturtevant, 1948, D. I. S. 22: 55--56 [New mutants report.] [FBrf0063893] Poulson, 1940, J. exp. Zool. 83: 271--325 The effects of certain X-chromosome deficiencies on the embryonic development of Drosophila melanogaster. [FBrf0005079] Noujdin, 1935, Zool. Zh. 14: 317--352 An investigation of an unstable chromosome in Drosophila melanogaster and of the mosaicism caused by it. [FBrf0003312]
Review	Wright, 1970, Adv. Genet. 15: 261--395 The genetics of embryogenesis in Drosophila. [FBrf0021061]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]
Book	Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster. The Genome of Drosophila melanogaster. [FBrf0066905]

Aberration Dmel\Df(1)sc8

Aberration Dmel\Df(1)sc⁸