Aberration Dmel\Df(1)su(s)83

General Information
Symbol	Dmel\Df(1)su(s)83	Species	D. melanogaster
Name		FlyBase ID	FBab0000971
Feature type	chromosomal_deletion
Also Known As	Df(1)su(s)⁸³

Computed Breakpoints include	1B10;1C3
Deleted segment	1B10--1C3
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor
Mutagen	gamma ray X ray (Voelker et al., 1989)
Class of aberration (relative to progenitor)	chromosomal_deletion (Voelker et al., 1989, Degelmann, 1993, Pauli et al., 1995, Duffy et al., 1996)
Breakpoints	1B7;1D6-1E1 (Degelmann, 1993) 1B10;1D6-1E1 (Voelker et al., 1989, Pauli et al., 1995, Duffy et al., 1996)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	l(1)1Bg << bk1 << l(1)1Bh << brc << bk2 << l(1)1Dc
Genetic mapping information
Comments
Comments on Cytology
	Limits of break 1 from polytene analysis (FBrf0049919) Left limit of break 2 from inclusion of brc (FBrf0049919) Right limit of break 2 from non-inclusion of l(1)1Dc (FBrf0049919)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	brc (Voelker et al., 1989) l(1)1Bh (Voelker et al., 1989) l(1)1Bi (Voelker et al., 1989, Duffy et al., 1996) l(1)1Bk (Voelker et al., 1989) l(1)1Ca (Voelker et al., 1989) l(1)1Da (Voelker et al., 1989) mul (Voelker et al., 1989) Rbf (Du and Dyson, 1999) RpL36 (Voelker et al., 1989, Duffy et al., 1996) skpA (Khush et al., 2002, Murphy, 2003) su(s) (Voelker et al., 1989) tw (Voelker et al., 1989)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	fs(1)A147 (Voelker et al., 1989) fs(1)M11 (Voelker et al., 1989) fs(1)M41 (Voelker et al., 1989) Klp3A (Voelker et al., 1989) l(1)1Bg (Voelker et al., 1989) l(1)1Dc (Voelker et al., 1989) rey (Voelker et al., 1989) su(w^a) (Voelker et al., 1989) Yp2 (Voelker et al., 1989)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	Acts as a dosage sensitive maternal modifier of run: causes tergite defects in greater than 65% of run³ heterozygotes. Shows a dominant Minute phenotype: short fine bristles, delayed development and reduced viability. Both phenotypes are alleviated by maternal P{1BD#1}. None of 79 females with germline clones for Df(1)su(s)83 were fecund: dissection revealed an agametic phenotype. (Duffy et al., 1996) Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovo^D2. (Pauli et al., 1995) Poor viability and fertility. Heterozygotes have poor viability and fertility. The Minute phenotype of Df(1)su(s)83/+ flies is resued by RpL36^+t10. (Voelker et al., 1989)
Stocks ( 2 )
Bloomington	3370 Df(1)su(s)83, y¹ cho¹ ras¹ v¹/Dp(1;Y)y²sc/C(1)DX, y¹ f¹
Kyoto	107014 Df(1)su(s)83, y¹ cho¹ ras¹ v¹/Dp(1;Y)y²sc/C(1)DX, y¹ f¹
Notes on Origin
Discoverer	Fleming.
	on y cho
Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	Df(1)su83 (Pauli et al., 1995) Df(1)Su(s)83 (Secombe et al., 1998) Df(1)su(s)83 (Nakamura et al., 2010) Df(1)su(s)⁸³ (Voelker et al., 1989, Eberl et al., 1988)
Name Synonym
Secondary FlyBase IDs

References ( 16 )
Research paper	Nakamura et al., 2010, Glycobiology 20(3): 381--394 Drosophila Dystroglycan is a target of O-mannosyltransferase activity of two protein O-mannosyltransferases, Rotated Abdomen and Twisted. [FBrf0209880] Lyalin et al., 2006, Genetics 172(1): 343--353 The twisted gene encodes Drosophila protein O-mannosyltransferase 2 and genetically interacts with the rotated abdomen gene encoding Drosophila protein O-mannosyltransferase 1. [FBrf0190741] Murphy, 2003, J. Cell Sci. 116(11): 2321--2332 Drosophila skpA, a component of SCF ubiquitin ligases, regulates centrosome duplication independently of cyclin E accumulation. [FBrf0159039] Khush et al., 2002, Curr. Biol. 12(20): 1728--1737 A ubiquitin-proteasome pathway represses the Drosophila immune deficiency signaling cascade. [FBrf0151852] Du and Dyson, 1999, EMBO J. 18(4): 916--925 The role of RBF in the introduction of G1 regulation during Drosophila embryogenesis. [FBrf0106433] Secombe et al., 1998, Genetics 149(4): 1867--1882 Analysis of a Drosophila cyclin E hypomorphic mutation suggests a novel role for cyclin E in cell proliferation control during eye imaginal disc development. [FBrf0103367] Nguyen et al., 1997, Development 124(17): 3303--3312 The sidekick gene, a member of the immunoglobulin superfamily, is required for pattern formation in the Drosophila eye. [FBrf0098319] Duffy et al., 1996, Genetics 142(3): 839--852 Dosage-sensitive maternal modifiers of the Drosophila segmentation gene runt. [FBrf0086390] Pauli et al., 1995, Genetics 139(2): 713--732 Identification of regions interacting with ovo^D mutations: Potential new genes involved in germline sex determination or differentiation in Drosophila melanogaster. [FBrf0080317] Pauli et al., 1995, D. I. S. 76: 107--124 Dose dependent enhancers and suppressors of ovoD2. [FBrf0082455] Degelmann, 1993, Mol. Gen. Genet. 239(1-2): 257--268 Genetic analysis of the X-chromosomal region 1E-2A of Drosophila melanogaster. [FBrf0059082] Lai and Mackay, 1993, Genet. Res. (Camb.) 61(3): 177--193 Mapping and characterization of P-element-induced mutations at quantitative trait loci in Drosophila melanogaster. [FBrf0058545] Voelker et al., 1989, Genetics 122: 625--642 Molecular and genetic organization of the suppressor of sable and Minute(1)1B region in Drosophila melanogaster. [FBrf0049919] Eberl et al., 1988, D. I. S. 67: 36 Determination of lethal phases of mutations in the su(s) microregion. [FBrf0047748]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]
Book	Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster. The Genome of Drosophila melanogaster. [FBrf0066905]