Aberration Dmel\Df(2L)A220

General Information
Symbol	Dmel\Df(2L)A220	Species	D. melanogaster
Name	Deficiency (2L) Aaron	FlyBase ID	FBab0001400
Feature type	chromosomal_deletion

Computed Breakpoints include	35B2;35C1-35C3
Deleted segment	35B2--35C3
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor
Mutagen	X ray (McNabb et al., 1996, Fossett et al., 1994)
Class of aberration (relative to progenitor)	chromosomal_deletion (McNabb et al., 1996, Roote et al., 1996)
Breakpoints	35B1-35B2;35B9 (McNabb et al., 1996, Roote et al., 1996)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	noc << bk1 << Adh << stc << bk2 << rd
Genetic mapping information
Comments	Breakpoint(s) molecularly mapped (Chia et al., 1985)
Comments on Cytology
	Left limit of break 1 from non-inclusion of noc (FBrf0038050) Right limit of break 1 from inclusion of Adh (FBrf0038050) Left limit of break 2 from inclusion of TfIIS (FBrf0073088) Right limit of break 2 from non-inclusion of esg (FBrf0073088)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	Adh (Ashburner et al., 1982, Fossett et al., 1994, McNabb et al., 1996) ck (Ashburner et al., 1982, Fossett et al., 1994) dyn-p25 (Ashburner et al., 1982) l(2)35Bc (Ashburner et al., 1982) l(2)35Bd (Ashburner et al., 1982) l(2)35Be (Ashburner et al., 1982) l(2)35Bg (Ashburner et al., 1982) mol (Ashburner et al., 1982, Fossett et al., 1994, McNabb et al., 1996) osp (Ashburner et al., 1982, Fossett et al., 1994, McNabb et al., 1996, Roote et al., 1996) stc (Ashburner et al., 1982, Fossett et al., 1994, Roote et al., 1996) Su(H) (Ashburner et al., 1982, Roote, 1996.5.20) TfIIS (Fossett et al., 1994)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	Ance (Ashburner et al., 1982, Fossett et al., 1994) Arpc1 (Ashburner et al., 1982) b (Ashburner et al., 1982) Ca-α1D (Fossett et al., 1994) Cul-3 (Ashburner et al., 1982, Fossett et al., 1994) CycE (Ashburner et al., 1982, Fossett et al., 1994) DNApol-γ35 (Ashburner et al., 1982) elA (Ashburner et al., 1982, Fossett et al., 1994) elB (Fossett et al., 1994) esg (Fossett et al., 1994) kuz (Fossett et al., 1994) l(2)34Db (Ashburner et al., 1982, Fossett et al., 1994) l(2)34Fc (Fossett et al., 1994, Ashburner et al., 1982) l(2)34Fd (Ashburner et al., 1982) l(2)35Cc (Fossett et al., 1994) l(2)35De (Fossett et al., 1994) lace (Ashburner et al., 1982, Fossett et al., 1994) mRpL4 (Fossett et al., 1994) NimA (Ashburner et al., 1982) NimC3 (Ashburner et al., 1982, Fossett et al., 1994) noc (Ashburner et al., 1982, Fossett et al., 1994, McNabb et al., 1996) pburs (Ashburner et al., 1982) Pgant35A (Ashburner et al., 1982, Fossett et al., 1994) rd (Ashburner et al., 1982) rk (Ashburner et al., 1982, Fossett et al., 1994) RpII33 (Ashburner et al., 1982, Fossett et al., 1994) sna (Ashburner et al., 1982, Fossett et al., 1994) Sos (Ashburner et al., 1982) tam (Ashburner et al., 1982) wb (Ashburner et al., 1982, Fossett et al., 1994) wek (Fossett et al., 1994) wor (Ashburner et al., 1982, Fossett et al., 1994)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	Mitotic phenotype of Su(H)^M28 is uncovered by Df(2L)A220, Su(H)^M28/Df(2L)A220 heterozygotes are lethal. (Roote, 1996.5.20)
Stocks ( 2 )
Bloomington	6059 Df(2L)A220, b¹ cn¹ bw¹/CyO, Adh^nB
Kyoto	108573 Df(2L)A220, b¹ cn¹ bw¹/CyO, Adh^nB
Notes on Origin
Discoverer	Aaron.
	selected as ADH null on 1-penten-3-ol.
Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	A220 (Fossett et al., 1994) Df(2L)A220
Name Synonym	Deficiency (2L) Aaron
Secondary FlyBase IDs

References ( 9 )
Research paper	McNabb et al., 1996, Genetics 143(2): 897--911 The alcohol dehydrogenase gene is nested in the outspread locus of Drosophila melanogaster. [FBrf0087599] Roote et al., 1996, D. I. S. 77: 55--65 Aberrations in the l(2)34Fc - l(2)35Bb region of chromosome arm 2L. [FBrf0091422] Fossett et al., 1994, Mutat. Res. 307(1): 213--222 The influence of large deletions on the mutation frequency induced by tritiated water and X-radiation in male Drosophila melanogaster post-meiotic germ cells. [FBrf0073088] Ashburner et al., 1990, Genetics 126: 679--694 The genetics of a small autosomal region of Drosophila melanogaster containing the structural gene for alcohol dehydrogenase. [FBrf0051973] Chia et al., 1985, J. Mol. Biol. 186(2): 689--706 Molecular analysis of the Adh region of the genome of Drosophila melanogaster. [FBrf0043115] Ashburner et al., 1982, Genetics 102: 421--435 The genetics of a small autosomal region of Drosophila melanogaster, including the structural gene for alcohol dehydrogenase. [FBrf0038050]
Personal communication to FlyBase	Roote, 1996.5.20, 35B. 35B. [FBrf0086797]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]
Book	Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster. The Genome of Drosophila melanogaster. [FBrf0066905]