Aberration Dmel\Df(2L)A263

General Information
Symbol	Dmel\Df(2L)A263	Species	D. melanogaster
Name	Deficiency (2L) Aaron	FlyBase ID	FBab0001405
Feature type	chromosomal_deletion
Also Known As	A263

Computed Breakpoints include	34E5-34F1;35C3
Deleted segment	34E5--35C3
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor
Mutagen	X ray
Class of aberration (relative to progenitor)	chromosomal_deletion (Ashburner et al., 1990, Furukawa et al., 1992)
Breakpoints	34E5-34F1;35C3-35C5 (Ashburner et al., 1990, Furukawa et al., 1992)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	rk << bk1 << l(2)34Fa << gft << bk2 << esg
Genetic mapping information
Comments
Comments on Cytology
	Limits of break 1 from polytene analysis (FBrf0051973) Left limit of break 2 from inclusion of gft (FBrf0038050) Right limit of break 2 from non-inclusion of esg (FBrf0055544)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	Adh (Ashburner et al., 1982, Furukawa et al., 1992) ck (Ashburner et al., 1982, Furukawa et al., 1992) Cul-3 (Ashburner et al., 1982, Furukawa et al., 1992) dyn-p25 (Ashburner et al., 1982, Furukawa et al., 1992) elA (Ashburner et al., 1982) l(2)34Fc (Ashburner et al., 1982) l(2)34Fd (Ashburner et al., 1982) l(2)35Bc (Furukawa et al., 1992, Ashburner et al., 1982) l(2)35Bd (Ashburner et al., 1982, Furukawa et al., 1992) l(2)35Be (Ashburner et al., 1982, Furukawa et al., 1992) l(2)35Bg (Ashburner et al., 1982, Furukawa et al., 1992) l(2)35Cc (Furukawa et al., 1992) mol (Ashburner et al., 1982, Furukawa et al., 1992) ms(2)35Ci (Ashburner et al., 1999, Ashburner et al., 1999.10.12) nht (Ashburner et al., 1999.10.12, Hiller et al., 2004) NimC3 (Ashburner et al., 1982) noc (Ashburner et al., 1982) osp (Ashburner et al., 1982) pburs (Ashburner et al., 1982) Pgant35A (Ashburner et al., 1982) rd (Ashburner et al., 1982, Furukawa et al., 1992) stc (Ashburner et al., 1982, Furukawa et al., 1992) Su(H) (Ashburner et al., 1982, Furukawa et al., 1992) TfIIS (Furukawa et al., 1992) vas (Furukawa et al., 1992) wb (Ashburner et al., 1982)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	Ance (Ashburner et al., 1982) Arpc1 (Ashburner et al., 1982) b (Ashburner et al., 1982) CycE (Ashburner et al., 1982, Furukawa et al., 1992) DNApol-γ35 (Ashburner et al., 1982) esg (Furukawa et al., 1992) l(2)34Db (Ashburner et al., 1982) l(2)35De (Furukawa et al., 1992) l(2)35Df (Furukawa et al., 1992) lace (Ashburner et al., 1982, Furukawa et al., 1992) NimA (Ashburner et al., 1982) rk (Eriksen et al., 2000, Ashburner et al., 1982) RpII33 (Ashburner et al., 1982) sna (Ashburner et al., 1982, Furukawa et al., 1992) Sos (Ashburner et al., 1982) tam (Ashburner et al., 1982) wor (Ashburner et al., 1982, Furukawa et al., 1992)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	The Df(2L)A263 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion). (Mason et al., 2004)
Stocks ( 2 )
Bloomington	6062 Df(2L)A263, b¹ cn¹ bw¹/CyO, Adh^nB
Kyoto	108576 Df(2L)A263, b¹ cn¹ bw¹/CyO, Adh^nB
Notes on Origin
Discoverer	Aaron.
	selected as ADH null on 1-penten-3-ol.
Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	41612 (Eriksen et al., 2000) A263 (Ashburner et al., 1999.10.12, Furukawa et al., 1992) Df(2L)A263 (Moschetti et al., 2004)
Name Synonym	Deficiency (2L) Aaron
Secondary FlyBase IDs

References ( 13 )
Research paper	Hiller et al., 2004, Development 131(21): 5297--5308 Testis-specific TAF homologs collaborate to control a tissue-specific transcription program. [FBrf0180166] Mason et al., 2004, Genetics 168(3): 1353--1370 A deficiency screen for dominant suppressors of telomeric silencing in Drosophila. [FBrf0180277] Moschetti et al., 2004, Mol. Genet. Genomics 271: 394--401 FB elements can promote exon shuffling: a promoter-less white allele can be reactivated by FB mediated transposition in Drosophila melanogaster. [FBrf0186074] Eriksen et al., 2000, Genome Res. 10(7): 924--938 Molecular cloning, genomic organization, developmental regulation, and a knock-out mutant of a novel leu-rich repeats-containing G protein-coupled receptor (DLGR-2) from Drosophila melanogaster. [FBrf0128457] Pasyukova et al., 2000, Genetics 156(3): 1129--1146 Deficiency mapping of quantitative trait loci affecting longevity in Drosophila melanogaster. [FBrf0131237] Ashburner et al., 1999, Genetics 153(1): 179--219 An exploration of the sequence of a 2.9-Mb region of the genome of Drosophila melanogaster. The Adh region. [FBrf0111326] Furukawa et al., 1992, Cell 69: 1191--1197 The Drosophila homolog of the immunoglobulin recombination signal-binding protein regulates peripheral nervous system development. [FBrf0055544] Ashburner et al., 1990, Genetics 126: 679--694 The genetics of a small autosomal region of Drosophila melanogaster containing the structural gene for alcohol dehydrogenase. [FBrf0051973] Ashburner et al., 1982, Genetics 102: 421--435 The genetics of a small autosomal region of Drosophila melanogaster, including the structural gene for alcohol dehydrogenase. [FBrf0038050] Ashburner et al., 1982, Genetics 102: 401--420 The genetics of a small chromosome region of Drosophila melanogaster containing the structural gene for Alcohol dehydrogenase. [FBrf0038047]
Personal communication to FlyBase	Ashburner et al., 1999.10.12, Adh. Adh. [FBrf0112153]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]
Book	Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster. The Genome of Drosophila melanogaster. [FBrf0066905]