FB2021_02, released April 13, 2021

Aberration: Dmel\Df(2L)A48

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General Information
Symbol
Df(2L)A48
Species
D. melanogaster
Name
Deficiency (2L) Aaron
FlyBase ID
FBab0001416
Feature type
chromosomal_deletion
Computed Breakpoints include

35B2;35D5

Features within 35B2--35D5
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
X ray
(McNabb et al., 1996, Fossett et al., 1994, Grau et al., 1984)
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Tinker et al., 1998, Duffy et al., 1996, McNabb et al., 1996, Rodriguez et al., 1996, Roote et al., 1996, Gubb et al., 1990, Gubb et al., 1985, Grau et al., 1984, Gubb et al., 1984, Ashburner et al., 1983, Ashburner et al., 1982)
Breakpoints

35B3;35D5-35D7

(Grau et al., 1984, Ashburner et al., 1982)

35B1-35B2;35D5-35D7

(Gubb et al., 1985, Ashburner et al., 1983)

35B2-35B3;35D5-35D7

(Duffy et al., 1996, McNabb et al., 1996, Rodriguez et al., 1996, Roote et al., 1996, Gubb et al., 1984)

35B2;35D5-35D7

(Tinker et al., 1998)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

noc << bk1 << Adh << lace << bk2 << CycE

Genetic mapping information
Comments

Breakpoint(s) molecularly mapped

(Chia et al., 1985)
Comments on Cytology

Ref: FBrf0038050.

(Grau et al., 1984)

Left limit of break 1 from polytene analysis (FBrf0040529) Right limit of break 1 from inclusion of Adh (FBrf0038047) Left limit of break 2 from polytene analysis (FBrf0038047) Right limit of break 2 from non-inclusion of CycE (FBrf0038047)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Adh
(Roote, 2002.1.15, McNabb et al., 1996, Roote et al., 1996, Fossett et al., 1994, Gubb et al., 1990, Grau et al., 1984, Ashburner et al., 1982, Ashburner et al., 1982)
Ankrd49
(Ashburner et al., 1982)
CG15269
(BDGP Project Members, 1994-1999)
CIAPIN1
(Spradling et al., 1999, BDGP Project Members, 1994-1999, Ashburner et al., 1982, Ashburner et al., 1982)
ck
(Cai et al., 2001, Spradling et al., 1999, BDGP Project Members, 1994-1999, Fossett et al., 1994, Grau et al., 1984, Ashburner et al., 1982, Ashburner et al., 1982)
Cul3
(Cai et al., 2001, Spradling et al., 1999, BDGP Project Members, 1994-1999, Fossett et al., 1994, Ashburner et al., 1982, Ashburner et al., 1982)
DCTN5-p25
(Ashburner et al., 1982)
esg
(Cai et al., 2001, Spradling et al., 1999, Rodriguez et al., 1996, Tanaka-Matakatsu et al., 1996, BDGP Project Members, 1994-1999, Fossett et al., 1994)
l(2)35Cg
(Cai et al., 2001)
l(2)35Ch
(Cai et al., 2001)
lace
(Roote et al., 1996, BDGP Project Members, 1994-1999, Fossett et al., 1994, Grau et al., 1984, Ashburner et al., 1982, Ashburner et al., 1982)
mol
(McNabb et al., 1996, Roote et al., 1996, Fossett et al., 1994, Gubb et al., 1990, Grau et al., 1984, Ashburner et al., 1982, Ashburner et al., 1982)
ms(2)35Dj
(Roote, 2010.1.4)
osp
(Ashraf et al., 1999, McNabb et al., 1996, Roote et al., 1996, Fossett et al., 1994, Gubb et al., 1990, Grau et al., 1984, Ashburner et al., 1982, Ashburner et al., 1982)
PolD3
(Grau et al., 1984, Ashburner et al., 1982, Ashburner et al., 1982)
Rnmt
(Spradling et al., 1999, BDGP Project Members, 1994-1999, Ashburner et al., 1982)
sna
(Cai et al., 2001, Fossett et al., 1994, Grau et al., 1984, Ashburner et al., 1982, Ashburner et al., 1982)
stc
(Cai et al., 2001, Spradling et al., 1999, Fossett et al., 1994, Grau et al., 1984, Ashburner et al., 1982, Ashburner et al., 1982)
Su(H)
(Ma et al., 2009, Spradling et al., 1999, BDGP Project Members, 1994-1999, Grau et al., 1984, Ashburner et al., 1982)
TfIIS
(Cai et al., 2001, Fossett et al., 1994)
THG
(Gubb et al., 1990, Ashburner et al., 1982)
Uxt
(Cai et al., 2001, Fossett et al., 1994)
vas
(Cai et al., 2001, Tinker et al., 1998)
vig
(Cai et al., 2001)
wor
(Cai et al., 2001, Fossett et al., 1994, Grau et al., 1984, Ashburner et al., 1982, Ashburner et al., 1982)
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Ance
(Fossett et al., 1994, Gubb et al., 1990, Ashburner et al., 1982)
Arpc1
(Gubb et al., 1990, Ashburner et al., 1982)
b
(Gubb et al., 1990, Ashburner et al., 1982)
Ca-α1D
(Fossett et al., 1994)
CycE
(BDGP Project Members, 1994-1999, Fossett et al., 1994, Grau et al., 1984, Ashburner et al., 1982, Ashburner et al., 1982)
elA
(Roote et al., 1996, Fossett et al., 1994, Gubb et al., 1990, Grau et al., 1984, Ashburner et al., 1982, Ashburner et al., 1982)
elB
(Roote et al., 1996, BDGP Project Members, 1994-1999, Fossett et al., 1994, Grau et al., 1984)
fs(2)lto1
(Ashburner et al., 1999.10.12, Roote, 1997.12.2)
kuz
(Fossett et al., 1994)
l(2)34Db
(Fossett et al., 1994, Ashburner et al., 1982)
l(2)34Fc
(Roote et al., 1996, Fossett et al., 1994, Gubb et al., 1990, Ashburner et al., 1982, Ashburner et al., 1982)
l(2)34Fd
(Roote et al., 1996, Gubb et al., 1990, Ashburner et al., 1982)
l(2)35De
(Fossett et al., 1994)
l(2)k04207
(BDGP Project Members, 1994-1999)
l(2)k05614
(BDGP Project Members, 1994-1999)
l(2)k09017a
(BDGP Project Members, 1994-1999)
l(2)k09033
(BDGP Project Members, 1994-1999)
l(2)k09208
(BDGP Project Members, 1994-1999)
mRpL4
(Fossett et al., 1994)
ms(2)34Fe
(Roote et al., 1996, Gubb et al., 1990)
Mtr4
(BDGP Project Members, 1994-1999)
NimA
(Gubb et al., 1990, Ashburner et al., 1982)
NimC3
(Fossett et al., 1994, Gubb et al., 1990, Ashburner et al., 1982)
noc
(McNabb et al., 1996, Roote et al., 1996, Fossett et al., 1994, Gubb et al., 1990, Grau et al., 1984, Ashburner et al., 1982, Ashburner et al., 1982)
Orc5
(Gubb et al., 1990)
osp
(Spradling et al., 1999, BDGP Project Members, 1994-1999)
Pburs
(Roote et al., 1996, Gubb et al., 1990, Grau et al., 1984, Ashburner et al., 1982, Ashburner et al., 1982)
Pgant35A
(Roote et al., 1996, Fossett et al., 1994, Gubb et al., 1990, Ashburner et al., 1982, Ashburner et al., 1982)
PolG1
(Gubb et al., 1990, Ashburner et al., 1982)
PolG2
(Gubb et al., 1990, Ashburner et al., 1982)
Polr2C
(Fossett et al., 1994, Gubb et al., 1990, Ashburner et al., 1982)
rk
(Eriksen et al., 2000, Fossett et al., 1994, Gubb et al., 1990, Ashburner et al., 1982)
Sos
(Gubb et al., 1990, Ashburner et al., 1982)
vas
(BDGP Project Members, 1994-1999)
wb
(Fossett et al., 1994, Gubb et al., 1990, Ashburner et al., 1982)
wek
(BDGP Project Members, 1994-1999, Fossett et al., 1994)
Molecular Data
 
BicC
(Gamberi, 2010.7.23)
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location
    Phenotypic Data
    In combination with other aberrations

    Does not suppress the zeste phenotype in a z1 w11E4; Tp(1;2)TE35B homologue.

    (Gubb et al., 1990)

    No effect on In(1)wm4h position-effect variegation.

    (Wustmann et al., 1989)
    NOT in combination with other aberrations

    Df(2L)A48 embryos show defective neuroblast asymmetry.

    (Cai et al., 2001)

    Embryos have severe neural defects.

    (Ashraf et al., 1999)

    Dominantly causes tergite defects in less than 50% of run3 heterozygotes.

    (Duffy et al., 1996)

    Chromosome has no effect on the physical interaction between tandemly duplicated copies of w+ and z1, despite having breakpoints within the critical region.

    (Gubb et al., 1990)
    Stocks (3)
    Notes on Origin
    Discoverer

    Aaron.

     

    selected as ADH null on 1-penten-3-ol.

    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     

    Reported to delete Adhr in error; see FBrf0141768 for correction.

    (Roote et al., 1996)
    Synonyms and Secondary IDs (4)
    Reported As
    Symbol Synonym
    3213
    (Eriksen et al., 2000)
    A48
    (Ashburner et al., 1999.10.12, Fossett et al., 1994)
    Df(2L)A48
    (Gamberi, 2010.7.23, Roote, 2010.1.4, Ma et al., 2009, Munro et al., 2006)
    Name Synonyms
    Deficiency (2L) Aaron
    Secondary FlyBase IDs
      References (34)