Aberration Dmel\Df(2L)DS5

General Information
Symbol	Dmel\Df(2L)DS5	Species	D. melanogaster
Name		FlyBase ID	FBab0001434
Feature type	chromosomal_deletion

Computed Breakpoints include	38C7-38C10;39D3-39E1
Deleted segment	38C7--39E1
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Aberration
Cytological Order
Progenitor
Mutagen	triethylenemelamine
Class of aberration (relative to progenitor)	chromosomal_deletion (Carpenter, 1997.9.30)
Breakpoints	38C7-38C10;39D3-39E1 (Carpenter, 1997.9.30)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	HIS-C << bk2 << Low
Genetic mapping information
Comments
Comments on Cytology
	All limits from polytene analysis (FBrf0098598)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	cad (Butler et al., 2001) dia (Butler et al., 2001) Fs(2)Ket (Butler et al., 2001) Hr38 (Butler et al., 2001) ik2 (Butler et al., 2001) l(2)38DEa (Butler et al., 2001) l(2)38EFb (Butler et al., 2001) l(2)38EFd (Butler et al., 2001) l(2)01528 (Butler et al., 2001) l(2)k14505 (BDGP Project Members, 1994-1999) ms(2)38DEa (Butler et al., 2001) vari (Butler et al., 2001)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	barr (Butler et al., 2001) Df31 (BDGP Project Members, 1994-1999) l(2)38Ab (Butler et al., 2001) l(2)38Db (Butler et al., 2001) l(2)k06113 (BDGP Project Members, 1994-1999) Low (Bhadra et al., 1997) neb (Butler et al., 2001) spir (Butler et al., 2001)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations	The position effect variegation of the w gene seen in In(1)w^m4 flies is partially suppressed by one copy of Df(2L)DS5. (Ner et al., 2002) Viable and fertile in combination with Df(2L)pr9201. Viable, female fertile and male sterile in combination with Df(2L)pr-A16. Semilethal and female sterile in combination with Df(2L)pr2b. Semilethal in combination with Df(2L)pr8311. Lethal in combination with Df(2L)pr11. (Butler et al., 2001)
NOT in combination with other aberrations
Stocks ( 0 )

Notes on Origin
Discoverer
	Induced on an isogenic P{w^bcd.2.5}b^- pr¹ cn^- chromosome. (Carpenter, 1997.9.30)
Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	Df(2L)DS5 (Kao and Megraw, 2009) DS5 (Ner et al., 2002)
Name Synonym
Secondary FlyBase IDs

References ( 12 )
Research paper	Kao and Megraw, 2009, Curr. Biol. 19(11): 937--942 Centrocortin cooperates with centrosomin to organize Drosophila embryonic cleavage furrows. [FBrf0214291] Ner et al., 2002, Genetics 162(4): 1763--1774 A role for the Drosophila SU(VAR)3-9 protein in chromatin organization at the histone gene cluster and in suppression of position-effect variegation. [FBrf0155808] Berloco et al., 2001, Proc. Natl. Acad. Sci. U.S.A. 98(21): 12126--12131 The maternal effect gene, abnormal oocyte (abo), of Drosophila melanogaster encodes a specific negative regulator of histones. [FBrf0139792] Butler et al., 2001, Genetics 158(4): 1597--1614 Map position and expression of the genes in the 38 region of Drosophila. [FBrf0138405] Bhadra et al., 1997, Genetics 146(3): 903--917 A sex-influenced modifier in Drosophila that affects a broad spectrum of target loci including the histone repeats. [FBrf0094158] Moore et al., 1983, Genetics 105(2): 327--344 Histone gene multiplicity and position effect variegation in Drosophila melanogaster. [FBrf0039446]
Personal communication to FlyBase	Doerig, 1999.8.9, P lethals from Paul Lasko. P lethals from Paul Lasko. [FBrf0109616] Carpenter, 1997.9.30, Revised cytology of Df(2L)DS. Revised cytology of Df(2L)DS. [FBrf0098598] BDGP Project Members, 1994-1999, BDGP Project Members, 1994-1999, Berkeley Drosophila Genome Project. (Computer file) BDGP Project Members, 1994-1999, Berkeley Drosophila Genome Project. (Computer file) [FBrf0067338]
Abstract	Sinclair et al., 1980, Genetics 94(4/2): s96--s97 Isolation and preliminary characterization of putative histone gene deficiencies in Drosophila melanogaster. [FBrf0034964]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]
Book	Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster. The Genome of Drosophila melanogaster. [FBrf0066905]