Aberration Dmel\Df(2L)DS6

General Information
Symbol	Dmel\Df(2L)DS6	Species	D. melanogaster
Name		FlyBase ID	FBab0001435
Feature type	chromosomal_deletion

Computed Breakpoints include	38E2;39E7
Deleted segment	38E2--39E7
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Aberration
Cytological Order
Progenitor
Mutagen	triethylenemelamine
Class of aberration (relative to progenitor)	chromosomal_deletion (Pauli et al., 1995, Duffy et al., 1996, Sinclair et al., 1983)
Breakpoints	38F5;39E7 (Sinclair et al., 1983) 38F5;39E7-39F1 (Pauli et al., 1995, Duffy et al., 1996)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	l(2)38Ea << bk1 << l(2)38Eb << HIS-C << bk2 << Low
Genetic mapping information
Comments
Comments on Cytology
	Left limit of break 1 from non-inclusion of l(2)38Ea (FBrf0102956) Right limit of break 1 from inclusion of Hr38 (FBrf0102956) Limits of break 2 from polytene analysis (FBrf0039952)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	cad (Butler et al., 2001) dia (Kozlova et al., 1998) Fs(2)Ket (Butler et al., 2001, Kozlova et al., 1998) HIS-C (Sinclair et al., 1983) Hr38 (Kozlova et al., 1998, Butler et al., 2001) Itgβν (Reuter et al., 1993) l(2)38Eb (Kozlova et al., 1998, Butler et al., 2001) l(2)38EFb (Kozlova et al., 1998) l(2)38EFc (Kozlova et al., 1998) l(2)38EFd (Kozlova et al., 1998, Butler et al., 2001) l(2)38EFe (Kozlova et al., 1998) l(2)38EFf (Kozlova et al., 1998) l(2)01528 (Butler et al., 2001) tadr (Ni et al., 2008) vari (Bachmann et al., 2008, Kozlova et al., 1998)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	barr (Butler et al., 2001) ik2 (Kozlova et al., 1998, Butler et al., 2001) l(2)38Aa (Butler et al., 2001) l(2)38Ab (Butler et al., 2001) l(2)38Da (Kozlova et al., 1998) l(2)38Db (Kozlova et al., 1998) l(2)38Dc (Kozlova et al., 1998) l(2)38Dd (Kozlova et al., 1998) l(2)38De (Kozlova et al., 1998) Low (Bhadra et al., 1997) neb (Butler et al., 2001) spir (Butler et al., 2001) vls (Butler et al., 2001)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations	The position effect variegation of the w gene seen in In(1)w^m4 flies is partially suppressed by one copy of Df(2L)DS6. (Ner et al., 2002)
NOT in combination with other aberrations	Heterozygous flies show a reduced response of the M pacemaker neurons in the brain to Pdf. (Duvall and Taghert, 2012) Hemizygous mutants exhibit an acceleration of the S-Phase of mitosis in larval neuroblasts. (Fyodorov et al., 2004) The Df(2L)DS6 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion). (Mason et al., 2004) Dominantly causes tergite defects in less than 50% of run³ heterozygotes. (Duffy et al., 1996) Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovo^D2. (Pauli et al., 1995)
Stocks ( 2 )
Bloomington	2386 Df(2L)DS6, b¹ pr¹ cn¹/CyO, P{sevRas1.V12}FK1
Kyoto	107302 Df(2L)DS6, b¹ pr¹ cn¹/CyO =or= SM6a
Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	Df(2L)DS6 (Wehr et al., 2006, Crest et al., 2007, Kuranaga et al., 2006, Watanabe et al., 2011, Ni et al., 2008, Bachmann et al., 2008, Popkova et al., 2012, Duvall and Taghert, 2012) Df(2L)Ds6 (White et al., 2007) Df(2L)DS6b (Devenport and Brown, 2004) DS6 (Ner et al., 2002)
Name Synonym
Secondary FlyBase IDs

References ( 32 )

Generate a list of	All references relating to this aberration ( 32 )

List References by type	Research paper ( 28 ) Personal communication to FlyBase ( 1 ) Abstract ( 1 ) FlyBase analysis ( 1 ) Book ( 1 )
Recent research papers ( 3 )
	Duvall and Taghert, 2012, PLoS Biol. 10(6): e1001337 The Circadian Neuropeptide PDF Signals Preferentially through a Specific Adenylate Cyclase Isoform AC3 in M Pacemakers of Drosophila. [FBrf0218594] Popkova et al., 2012, PLoS Genet. 8(12): e1003159 Polycomb controls gliogenesis by regulating the transient expression of the gcm/glide fate determinant. [FBrf0220515] Watanabe et al., 2011, Behav. Genet. 41(5): 746--753 Gr39a, a Highly Diversified Gustatory Receptor in Drosophila, has a Role in Sexual Behavior. [FBrf0214804] Show all research papers ...