FlyBase Aberration Report: Dmel\Df(2L)DS6

General Information

Symbol

Df(2L)DS6

Species

D. melanogaster

Name

FlyBase ID

FBab0001435

Feature type

chromosomal_deletion

Computed Breakpoints include

38E2;39E7

Features within 38E2--39E7

Sequence coordinates

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

Progenitor

Mutagen

triethylenemelamine

Class of aberration (relative to wild type)

chromosomal_deletion

(FlyBase, 2007)

Class of aberration (relative to progenitor)

chromosomal_deletion

(Duffy et al., 1996, Pauli et al., 1995, Sinclair et al., 1983)

Breakpoints

38F5;39E7

(Sinclair et al., 1983)

38F5;39E7-39F1

(Duffy et al., 1996, Pauli et al., 1995)

Causes alleles

Carries alleles

Transposon Insertions

Formalized genetic data

l(2)38Ea << bk1 << l(2)38Eb << HIS-C << bk2 << Low

Genetic mapping information

Comments

Comments on Cytology

Left limit of break 1 from non-inclusion of l(2)38Ea (FBrf0102956) Right limit of break 1 from inclusion of Hr38 (FBrf0102956) Limits of break 2 from polytene analysis (FBrf0039952)

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

cad

(Butler et al., 2001)

dia

(Kozlova et al., 1998)

Fs(2)Ket

(Butler et al., 2001, Kozlova et al., 1998)

HIS-C

(Sinclair et al., 1983)

Hr38

(Butler et al., 2001, Kozlova et al., 1998)

Itgbn

(Reuter et al., 1993)

l(2)38Eb

(Butler et al., 2001, Kozlova et al., 1998)

l(2)38EFb

(Kozlova et al., 1998)

l(2)38EFc

(Kozlova et al., 1998)

l(2)38EFd

(Butler et al., 2001, Kozlova et al., 1998)

l(2)38EFe

(Kozlova et al., 1998)

l(2)38EFf

(Kozlova et al., 1998)

l(2)01528

(Butler et al., 2001)

tadr

(Ni et al., 2008)

vari

(Bachmann et al., 2008, Kozlova et al., 1998)

Partially deleted / disrupted

Molecular Data

Completely deleted

Partially deleted

Genes NOT Deleted / Disrupted

Complementation Data

barr

(Butler et al., 2001)

IKKε

(Butler et al., 2001, Kozlova et al., 1998)

l(2)38Aa

(Butler et al., 2001)

l(2)38Ab

(Butler et al., 2001)

l(2)38Da

(Kozlova et al., 1998)

l(2)38Db

(Kozlova et al., 1998)

l(2)38Dc

(Kozlova et al., 1998)

l(2)38Dd

(Kozlova et al., 1998)

l(2)38De

(Kozlova et al., 1998)

Low

(Bhadra et al., 1997)

neb

(Butler et al., 2001)

spir

(Butler et al., 2001)

vls

(Butler et al., 2001)

Molecular Data

Genes Duplicated

Complementation Data

Completely duplicated

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Affected Genes Inferred by Location (0)

If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
In these cases, there will be no "Export to Hitlist" button to the left.

Related Comments

Phenotypic Data

In combination with other aberrations

The position effect variegation of the w gene seen in In(1)w^m4 flies is partially suppressed by one copy of Df(2L)DS6.

(Ner et al., 2002)

NOT in combination with other aberrations

Heterozygous flies show a reduced response of the M pacemaker neurons in the brain to Pdf.

(Duvall and Taghert, 2012)

Hemizygous mutants exhibit an acceleration of the S-Phase of mitosis in larval neuroblasts.

(Fyodorov et al., 2004)

The Df(2L)DS6 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion).

(Mason et al., 2004)

Dominantly causes tergite defects in less than 50% of run³ heterozygotes.

(Duffy et al., 1996)

Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovo^D2.

(Pauli et al., 1995)

Stocks (2)

Bloomington

2386

Df(2L)DS6, Adc^b-1 pr¹ cn¹/CyO, P{sevRas1.V12}FK1

Kyoto

107302

Df(2L)DS6, Adc^b-1 pr¹ cn¹/CyO =or= SM6a

Notes on Origin

Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

DS6

(Ner et al., 2002)

Df(2L)DS6

(Iampietro et al., 2014, Duvall and Taghert, 2012, Popkova et al., 2012, Watanabe et al., 2011, Bachmann et al., 2008, Ni et al., 2008, Crest et al., 2007, Kuranaga et al., 2006, Wehr et al., 2006)

Df(2L)DS6b

(Devenport and Brown, 2004)

Df(2L)Ds6

(Salzler et al., 2013, White et al., 2007)

Name Synonyms

Secondary FlyBase IDs

References (34)

Report Sections

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