Aberration Dmel\Df(2L)E110

General Information
Symbol	Dmel\Df(2L)E110	Species	D. melanogaster
Name		FlyBase ID	FBab0001456
Feature type	chromosomal_deletion
Also Known As	E110

Computed Breakpoints include	25F3-26A1;26D3-26D11
Deleted segment	25F3--26D11
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor
Mutagen	P-element activity PM hybrid dysgenesis (Locke et al., 1988)
Class of aberration (relative to progenitor)	chromosomal_deletion (Locke et al., 1988)
Breakpoints	25F3-26A1;26D3-26D11 (Locke et al., 1988)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	bk1 << E(var)26A << bk2
Genetic mapping information
Comments
Comments on Cytology
	All limits from polytene analysis (FBrf0048198)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	E(var)26A (Locke et al., 1988) eIF-4a (Spradling et al., 1999, Li et al., 2005, BDGP Project Members, 1994-1999) l(2)k06107 (BDGP Project Members, 1994-1999) l(2)k06502 (Spradling et al., 1999, BDGP Project Members, 1994-1999) lid (Gildea et al., 2000) slmo (Carhan et al., 2004)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	cype (Spradling et al., 1999, BDGP Project Members, 1994-1999) Kr-h1 (Spradling et al., 1999, BDGP Project Members, 1994-1999) l(2)00455b (BDGP Project Members, 1994-1999) l(2)k03201 (BDGP Project Members, 1994-1999) l(2)k04909b (BDGP Project Members, 1994-1999) l(2)k07502b (Spradling et al., 1999, BDGP Project Members, 1994-1999) l(2)k09923 (Spradling et al., 1999, BDGP Project Members, 1994-1999) Lam (Spradling et al., 1999, BDGP Project Members, 1994-1999) PDZ-GEF (Spradling et al., 1999, BDGP Project Members, 1994-1999) S(CycE^JP)2.8 (Brumby et al., 2004) Sec61α (Beaton, 1997.3.4)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations	Dominantly enhances position effect variegation at the w locus caused by In(1)w^m4, C(1;YL)w^mMc or T(1;4)w^m5 and position effect variegation at the y locus caused by In(1)y^3P. Position effect variegation at the w locus is not seen when Df(2L)E110 is combined with In(1)w^m4rv5, In(1)w^m4rv6 or In(1)w^m4rv26. (Locke et al., 1988)
NOT in combination with other aberrations	The Df(2L)E110 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion). (Mason et al., 2004) Heterozygosity for Df(2L)E110 results in 2.6% X chromosome nondisjunction and 0.5% fourth chromosome nondisjunction in In(1)FM7/X ; sv^spa-pol females. (Harris et al., 2003) Wild-type clones made in the ovaries of a mutant female, are significantly larger than clones of heterozygous mutant cells. This size difference is greater in clones initiated at 48 hours after egg laying (AEL) than 2 hours AEL. (Extavour and Garcia-Bellido, 2001) Enhance mottling in w^m4. (Tartof et al., 1989) Homozygous lethal. (Locke et al., 1988) Enhances position-effect variegation of In(1)w^m4. Recessive lethal.
Stocks ( 2 )
Bloomington	490 In(1)w^m4; Df(2L)E110/CyO
Kyoto	108906 In(1)w^m4; Df(2L)E110/CyO
Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	Df(2L)E110 (Secombe et al., 2007, Schimmelpfeng et al., 2006, Casso et al., 2008) E110 (Locke et al., 1988, Tartof et al., 1989)
Name Synonym
Secondary FlyBase IDs

References ( 22 )

Generate a list of	All references relating to this aberration ( 22 )

List References by type	Research paper ( 18 ) Personal communication to FlyBase ( 2 ) FlyBase analysis ( 1 ) Book ( 1 )
Recent research papers (0)
	All research papers listed in FlyBase were published before 2011 Show research papers ...