Open Close
General Information
D. melanogaster
FlyBase ID
Feature type
Computed Breakpoints include
Sequence coordinates
2L:19,691,199..19,701,224 [+] (Df(2L)E55:bk2)
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Class of aberration (relative to wild type)
Carries alleles
Transposon Insertions
Formalized genetic data

γTub37C << bk1 << l(2)37Da << fs(2)lto3 << bk2 << Lar

Genetic mapping information

Breakpoint(s) molecularly mapped

Comments on Cytology

Left limit of break 1 from polytene analysis (FBrf0028752) Right limit of break 1 from inclusion of l(2)37Da (citation unavailable) Left limit of break 2 from inclusion of Lar (FBrf0086508) Right limit of break 2 from polytene analysis (FBrf0028752)

Sequence Crossreferences
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
Molecular Data
Affected Genes Inferred by Location
    Phenotypic Data
    In combination with other aberrations

    The width of the CNS is closer to wild-type in Df(2L)E55 ; Df(3L)H99 double mutant embryos than in Df(2L)E55 single mutant embryos, although commissure separation remains incomplete.

    No effect on In(1)wm4h position-effect variegation.

    Df(2L)E55/Df(2L)TW330 lethal Df(2L)E55/Df(2L)VA15 lethal Df(2L)E55/Df(2L)VA20 lethal Df(2L)E55/Df(2L)VA22 lethal Df(2L)E55/Df(2L)VA23 lethal Df(2L)E55/Df(2L)VA25 lethal Df(2L)E55/Df(2L)TW9 lethal Df(2L)E55/Df(2L)TW12 lethal Df(2L)E55/Df(2L)TW150 viable Df(2L)E55/Df(2L)TW84 viable Df(2L)E55/Df(2L)OD16 viable Df(2L)E55/Df(2L)TW150 non-transparent wing phenotype Df(2L)E55/Df(2L)TW84 non-transparent wing phenotype Df(2L)E55/Df(2L)OD16 non-transparent wing phenotype

    NOT in combination with other aberrations

    Heterozygosity for Df(2L)E55 results in 3.5% X chromosome nondisjunction and 2.4% fourth chromosome nondisjunction in In(1)FM7/X ; svspa-pol females.

    Shows no maternal enhancement of dpphr4.

    The central nervous system (CNS) is narrower than normal and the commissures are thicker than normal and incompletely separated in Df(2L)E55 embryos.

    Dominantly causes tergite defects in less than 50% of run3 heterozygotes.

    Midgut development of mutant embryos is wild type.

    Homozygous embryos do not always complete head involution.

    Heterozygosity for this deletion suppresses the mutant ovarian phenotype of ovoD2.

    Stocks (3)
    Notes on Origin
    Balancer / Genotype Variants of the Aberration
    Separable Components
    Other Comments

    The Df(2L)E55 chromosome acts as a dominant moderate suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion), but this is a false positive result (the suppressor is not within the bounds of the deficient region) because the region of the deficiency is covered by one or more nonsuppressing deficiencies.

    Synonyms and Secondary IDs (4)
    References (47)