cype << bk1 << l(2)25Ea << l(2)26Ad << bk2 << l(2)26Cf
Breakpoint(s) molecularly mapped
Df(2L)x528/Df(2L)Gpdh1-A is embryonic lethal and impacts founder cells for lateral transverse muscle 3, lateral transverse muscle 4, lateral oblique muscle 1 and ventral transverse muscle 1; loss of lateral transverse muscles.
Df(2L)x528/Df(2L)Gpdh1-A embryos show a loss of neuroblasts NB1-1, NB2-5 and NB2-4. This loss is much more pronounced in odd-numbered than even-numbered abdominal segments. However, the loss is similar to mid mutants, suggesting that the it is deletion of the mid gene and not the H15 gene that is causing the phenotype.
Df(2L)Gpdh1-A/Df(2L)x528 larvae show a loss of denticle belts; denticle rows 1 to 5 are frequently lost in odd-numbered segments, whereas even-numbered segments show milder defects. Df(2L)H15-x4/Df(2L)Gpdh1-A larvae show a weak loss of denticles phenotype.
Midgut development of mutant embryos is wild type.
Homozygous embryos are very abnormal compared to wild-type. The hindgut is short and broad, and the Malpighian tubules do not elongate.
Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovoD2.
Enhance mottling in wm4.