A Database of Drosophila Genes & Genomes

FB2008_06, released July 3, 2008
 

Aberration Dmel\Df(2L)GpdhA

General Information
SymbolDmel\Df(2L)GpdhASpeciesD. melanogaster
NameFlyBase IDFBab0001468
Feature typechromosomal_deletionCreated / Updated2006-08-22/2006-08-22
Formalized genetic data cype << bk1 << l(2)25Ea << l(2)26Ad << bk2 << l(2)26Cf
Sequence coordinates
Deleted segment25D7--26A9
Duplicated segment
Computed Breakpoints include 25D7;26A8-26A9
Breakpoints Inherited  
hide Nature of the Aberration
Cytological Order
Progenitor
Mutagen
X ray
(Kotarski et al., 1983, Knipple and MacIntyre, 1984)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Pauli et al., 1995, de Belle et al., 1989, Duffy et al., 1996, Knipple and MacIntyre, 1984, Harbecke and Lengyel, 1995, Giansanti et al., 1998, Locke et al., 1988, Aguade, 1998, Basu and Li, 1998, Racine et al., 1980)
Breakpoints
25E2-25E4;26B3-26B9
(Racine et al., 1980)
25E1-25E2;26A8-26A9
(Knipple and MacIntyre, 1984)
25D7;26A8-26A9
(Locke et al., 1988, Aguade, 1998)
25D7-25E1;26A8-26A9
(de Belle et al., 1989, Pauli et al., 1995, Harbecke and Lengyel, 1995, Duffy et al., 1996, Giansanti et al., 1998, Basu and Li, 1998)
Causes alleles
Carries alleles
Transposon Insertions
Genetic mapping information
Comments
Breakpoint(s) molecularly mapped
(Knipple et al., 1991)
hide Comments on Cytology
Limits of break 1 from polytene analysis (FBrf0048198) Left limit of break 2 from inclusion of lid (FBrf0067338) Right limit of break 2 from polytene analysis (FBrf0041503)
 
H2.0 maps (by in situ hybridisation) to the right of the Df(2L)GpdhA deficiency.
(Barad et al., 1988)
hide Molecularly Mapped Breakpoints
 
hide Sequence Crossreferences
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
hide Gene Deletion & Duplication Data
hide Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
H15
(Miskolczi-McCallum et al., 2005)
tkv
(Harbecke and Lengyel, 1995)
mid
(Tearle and Nusslein-Volhard, 1987, Harbecke and Lengyel, 1995, Miskolczi-McCallum et al., 2005)
cl
(Kotarski et al., 1983)
Lam
(Kotarski et al., 1983, BDGP Project Members, 1994-1999, Guillemin, 1997.6.19, Spradling et al., 1999, Guillemin et al., 2001, Osouda et al., 2005)
Hel25E
(Kotarski et al., 1983)
CG31647
(Miskolczi-McCallum et al., 2005)
Gpdh
(Racine et al., 1980, Kotarski et al., 1983)
Acp26Aa
(Aguade, 1998)
Acp26Ab
(Aguade, 1998)
eIF-4a
(Kotarski et al., 1983, Dorn et al., 1993, BDGP Project Members, 1994-1999, Beaton, 1997.3.4, Spradling et al., 1999, Li et al., 2005)
ifc
(Kotarski et al., 1983, Castrillon et al., 1993, BDGP Project Members, 1994-1999, Basu and Li, 1998, Spradling et al., 1999)
Gal
(Knipple and MacIntyre, 1984)
lid
(BDGP Project Members, 1994-1999, Spradling et al., 1999, Gildea et al., 2000)
chic
(Castrillon et al., 1993, BDGP Project Members, 1994-1999, Giansanti et al., 1998, Wills et al., 1999, Spradling et al., 1999)
milt
(BDGP Project Members, 1994-1999)
l(2)k07109a
(BDGP Project Members, 1994-1999)
l(2)k06502
(BDGP Project Members, 1994-1999)
E(var)26A
(Locke et al., 1988)
l(2)25Fe
(Kotarski et al., 1983)
l(2)25Fd
(Kotarski et al., 1983)
l(2)25Fa
(Kotarski et al., 1983)
l(2)PN-11
(Racine et al., 1980)
l(2)PN-6
(Racine et al., 1980)
l(2)25Ef
(Kotarski et al., 1983)
l(2)25Ee
(Kotarski et al., 1983)
l(2)25Fb
(Kotarski et al., 1983)
l(2)26Ae
(Kotarski et al., 1983)
l(2)25Ed
(Kotarski et al., 1983)
l(2)25Eg
(Kotarski et al., 1983)
l(2)25Fc
(Kotarski et al., 1983)
l(2)26Ad
(Kotarski et al., 1983)
l(2)25Ea
(Kotarski et al., 1983)
Molecular Data
Completely deleted
H15
(Buescher et al., 2004)
mid
(Buescher et al., 2004)
CG31647
(Buescher et al., 2004)
hide Genes NOT Deleted / Disrupted
Complementation Data
vri
(BDGP Project Members, 1994-1999)
cype
(BDGP Project Members, 1994-1999, Spradling et al., 1999)
tkv
(Kotarski et al., 1983)
Kr-h1
(BDGP Project Members, 1994-1999, Spradling et al., 1999)
wg
(Kotarski et al., 1983)
qua
(Bloomington Drosophila Stock Center, 1998.9.22)
dp
(Kotarski et al., 1983)
for
(de Belle et al., 1989)
l(2)04884
(BDGP Project Members, 1994-1999)
l(2)k04909b
(BDGP Project Members, 1994-1999)
l(2)26Cf
(Kotarski et al., 1983)
M(2)25C
(Kotarski et al., 1983)
Molecular Data
hide Genes Duplicated
Complementation Data
Molecular Data
hide Genes NOT Duplicated
Complementation Data
Molecular Data
hide Related Comments
hide Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations
Dominantly causes tergite defects in less than 50% of run3 heterozygotes.
(Duffy et al., 1996)
Enhance mottling in wm4.
(Tartof et al., 1989)
Heterozygosity for Df(2L)GpdhA results in 8.0% X chromosome nondisjunction and 2.2% fourth chromosome nondisjunction in In(1)FM7/X ; svspa-pol females.
(Harris et al., 2003)
Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovoD2.
(Pauli et al., 1995)
Homozygous embryos are very abnormal compared to wild-type. The hindgut is short and broad, and the Malpighian tubules do not elongate.
(Harbecke and Lengyel, 1995)
Midgut development of mutant embryos is wild type.
(Bilder and Scott, 1995)
Shows no maternal enhancement of dpphr4.
(Nicholls and Gelbart, 1998)
hide Position Effect Variegation Data
  
hide Stocks ( 2 )
Kyoto
106215
Df(2L)GpdhA/CyO
Bloomington
1128
Df(2L)GpdhA/CyO, P{sevRas1.V12}FK1
hide Notes on Origin
Discoverer
hide Balancer / Genotype Variants of the Aberration
    hide Separable Components
      hide Other Comments
      hide Synonyms & Secondary IDs ( 12 )
      Reported As
      Symbol Synonym
      Df(2)GdhA
      (Verheyen and Cooley, 1994)
      Df(2L)GdhA
      (Wilanowski et al., 1998)
      Df(2L)gdh-A
      (Osouda et al., 2005)
      Df(2L)Gdh-A
      (Abrell et al., 2000)
      Df(2L)GdhA
      (Bewley, 1981, Locke et al., 1988, Tearle and Nusslein-Volhard, 1987, Bewley, 1983, Knipple and MacIntyre, 1984, de Belle et al., 1989, Kotarski et al., 1983, Dorn et al., 1993, Symonds and Gibson, 1992, Tartof et al., 1989, )
      Df(2L)Gdh-A,dpL
      (Aguade, 1998)
      Df(2L)GpdhA
      (Gibson et al., 1990)
      Df(2L)GpdhA
      (Crest et al., 2007)
      Df(2L)GpdHA
      (Buescher et al., 2006)
      Df-GpdhA
      (Buescher et al., 2004)
      GpdhA
      (Yamaguchi et al., 2001)
      Name Synonym
      GdhA deficiency
      (Barad et al., 1988)
      Secondary FlyBase IDs
        hide References ( 57 )
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        hide Recent research papers ( 2 )
        Crest et al., 2007, Genetics 175(2): 567--584
        Onset of the DNA replication checkpoint in the early Drosophila embryo. [FBrf0194644]
        Buescher et al., 2006, Dev. Biol. 292(2): 418--429
        Functions of the segment polarity genes midline and H15 in Drosophila melanogaster neurogenesis. [FBrf0190096]
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