|Also Known As||Df(2L)GdhA, Df(2L)gdh-A|
|Computed Breakpoints include||25D7;26A8-26A9|
|Member of large scale dataset(s)|
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|Nature of the Aberration|
|Class of aberration (relative to progenitor)|
|Formalized genetic data||cype << bk1 << l(2)25Ea << l(2)26Ad << bk2 << l(2)26Cf|
|Genetic mapping information|
Breakpoint(s) molecularly mapped
|Comments on Cytology|
|Gene Deletion & Duplication Data|
|Genes Deleted / Disrupted|
|Completely deleted / disrupted|
|Genes NOT Deleted / Disrupted|
|Genes NOT Duplicated|
|In combination with other aberrations|
Df(2L)x528/Df(2L)GpdhA embryos show a loss of neuroblasts NB1-1, NB2-5 and NB2-4. This loss is much more pronounced in odd-numbered than even-numbered abdominal segments. However, the loss is similar to mid mutants, suggesting that the it is deletion of the mid gene and not the H15 gene that is causing the phenotype.
Df(2L)GpdhA/Df(2L)x528 larvae show a loss of denticle belts; denticle rows 1 to 5 are frequently lost in odd-numbered segments, whereas even-numbered segments show milder defects. Df(2L)H15-x4/Df(2L)GpdhA larvae show a weak loss of denticles phenotype.
Enhances position effect variegation at the w locus caused by In(1)wm4, C(1;YL)wmMc or T(1;4)wm5 and position effect variegation at the y locus caused by In(1)y3P.
|NOT in combination with other aberrations|
Heterozygosity for Df(2L)GpdhA results in 8.0% X chromosome nondisjunction and 2.2% fourth chromosome nondisjunction in In(1)FM7/X ; svspa-pol females.
Midgut development of mutant embryos is wild type.
Homozygous embryos are very abnormal compared to wild-type. The hindgut is short and broad, and the Malpighian tubules do not elongate.
Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovoD2.
Enhance mottling in wm4.
|Stocks ( 2 )|
|Notes on Origin|
|Balancer / Genotype Variants of the Aberration|
|Synonyms & Secondary IDs ( 14 )|
|Secondary FlyBase IDs|
|References ( 60 )|
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|Recent research papers ( 1 )|
|Recent reviews (0)|
|All reviews listed in FlyBase were published before 2011|