A Database of Drosophila Genes & Genomes

FB2013_03, released May 7th, 2013
 

Aberration Dmel\Df(2L)H20

General Information
SymbolDmel\Df(2L)H20SpeciesD. melanogaster
NameFlyBase IDFBab0001470
Feature typechromosomal_deletion
Also Known AsDf(2L)H2, Df(2)H20, H20
Computed Breakpoints include 36A8-36A9;36F1
Deleted segment36A8--36F1
Map ( GBrowse ) GBrowse View Help Untitled Document

Error

No matching regions found.

Sequence coordinates
2L:16,686,357..16,689,573 [+] (Df(2L)H20:bk1)
(Li and Baker, 1998)
Member of large scale dataset(s)
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Description
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FB2013_03
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hide Nature of the Aberration
Cytological Order
Progenitor
Mutagen
X ray
(Steward and Nusslein-Volhard, 1986, Simpson, 1983)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Steward and Nusslein-Volhard, 1986, Simpson, 1983, Pultz et al., 1994, Pauli et al., 1995, Homyk and Emerson, 1988, Duffy et al., 1996, Fitzpatrick et al., 1995, Harbecke and Lengyel, 1995, Landecker et al., 1994, Whalen and Wilson, 1986)
Breakpoints
36A6-36A7;36F1-36F2
(Homyk and Emerson, 1988)
36A6-36A10;36E3-36F2
(Steward and Nusslein-Volhard, 1986)
36A6-36A11;36E3-36F2
(Pultz et al., 1994)
36A8-36A9;36E1-36E2
(Schupbach and Wieschaus, 1989, Pauli et al., 1995, Harbecke and Lengyel, 1995, Duffy et al., 1996)
36A8-36A9;36E3-36E4
(Whalen and Wilson, 1986, Landecker et al., 1994, Fitzpatrick et al., 1995)
36A12-36A14;36E1-36E2
(Simpson, 1983)
Causes alleles
Fas3H20
(Marygold, 2005.1.19)
Carries alleles
Transposon Insertions
Formalized genetic data her << bk1 << l(2)k04206 << bk2 << Dox-A3
Genetic mapping information
Comments
hide Comments on Cytology
Ref: Ashburner et al., 1990, Genetics 126: 679--694
(Pultz et al., 1994)
Ref: FBrf0045239.
(Homyk and Emerson, 1988)
Limits of break 1 from polytene analysis (FBrf0044474) Left limit of break 2 from polytene analysis (FBrf0048188) Right limit of break 2 from polytene analysis (FBrf0044468)
 
hide Sequence Crossreferences
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
hide Gene Deletion & Duplication Data
hide Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Aac11
(Spradling et al., 1999, BDGP Project Members, 1994-1999, Morris et al., 2006)
AcpC
(Whalen and Wilson, 1986)
BicD
(Steward and Nusslein-Volhard, 1986, Schupbach and Wieschaus, 1991)
bst
(Boquet et al., 2000)
CadN
(Brumby et al., 2004, Steward and Nusslein-Volhard, 1986)
Cas
(Spradling et al., 1999, BDGP Project Members, 1994-1999)
Cyt-c-d
(Castrillon et al., 1993)
dl
(Steward and Nusslein-Volhard, 1986, Schupbach and Wieschaus, 1989, Schupbach and Wieschaus, 1991)
Dox-3
(Rizki et al., 1985)
E(var)36AE
(Wustmann et al., 1989)
fs(2)ltoHC44
(Schupbach and Wieschaus, 1991)
glu
(Spradling et al., 1999, BDGP Project Members, 1994-1999, Kania et al., 1995)
grp
(Li and Baker, 1998, Spradling et al., 1999, BDGP Project Members, 1994-1999)
kel
(Steward and Nusslein-Volhard, 1986, Schupbach and Wieschaus, 1991)
l(2)36Aa
(Steward and Nusslein-Volhard, 1986, Ashburner et al., 1990)
l(2)36Ab
(Steward and Nusslein-Volhard, 1986, Ashburner et al., 1990)
l(2)36Ac
(Steward and Nusslein-Volhard, 1986, Ashburner et al., 1990)
l(2)36Ad
(Steward and Nusslein-Volhard, 1986, Ashburner et al., 1990)
l(2)36Ba
(Steward and Nusslein-Volhard, 1986)
l(2)36Bb
(Steward and Nusslein-Volhard, 1986)
l(2)36Bc
(Steward and Nusslein-Volhard, 1986)
l(2)36Bd
(Steward and Nusslein-Volhard, 1986)
l(2)36Ca
(Steward and Nusslein-Volhard, 1986)
l(2)k04206
(Roote, 1998.11.16)
l(2)k13905
(Spradling et al., 1999, BDGP Project Members, 1994-1999)
mdy
(Schupbach and Wieschaus, 1991)
Mhc
(Kronert et al., 1999, Cripps et al., 1994, Nongthomba et al., 2003, Homyk and Emerson, 1988, Spradling et al., 1999, Montana and Littleton, 2004, Steward and Nusslein-Volhard, 1986, BDGP Project Members, 1994-1999, Nongthomba and Ramachandra, 1999, Babu and Ramachandra, 2007)
ninaD
(Steward and Nusslein-Volhard, 1986)
plo
(Steward and Nusslein-Volhard, 1986, Ashburner et al., 1990)
Ptp36E
(Fitzpatrick et al., 1995)
qua
(Steward and Nusslein-Volhard, 1986, Schupbach and Wieschaus, 1991)
rdo
(Steward and Nusslein-Volhard, 1986)
Molecular Data
Completely deleted
Acp36DE
(Marygold, 2005.1.19)
Partially deleted
Fas3
(Marygold, 2005.1.19)
hide Genes NOT Deleted / Disrupted
Complementation Data
BicC
(Ashburner et al., 1990)
bun
(BDGP Project Members, 1994-1999)
cact
(Tearle and Nusslein-Volhard, 1987, Ashburner et al., 1990)
Ca-α1D
(Ashburner et al., 1990)
chif
(Ashburner et al., 1990)
ck
(Ashburner et al., 1990)
cni
(Ashburner et al., 1990)
crp
(Ashburner et al., 1990)
Cul-3
(Ashburner et al., 1990)
CycE
(Ashburner et al., 1990)
Cyp303a1
(Ashburner et al., 1990)
dac
(Ashburner et al., 1990)
esg
(Ashburner et al., 1990)
fzy
(Ashburner et al., 1990)
Gli
(Ashburner et al., 1990)
heix
(Ashburner et al., 1990)
her
(Li and Baker, 1998, Pultz et al., 1994)
l(2)35Cc
(Ashburner et al., 1990)
l(2)35De
(Ashburner et al., 1990)
l(2)35Df
(Ashburner et al., 1990)
l(2)35Di
(Ashburner et al., 1990)
l(2)k07020
(BDGP Project Members, 1994-1999)
l(2)k09927
(BDGP Project Members, 1994-1999)
l(2)k10816
(BDGP Project Members, 1994-1999)
l(2)k16215
(BDGP Project Members, 1994-1999)
l(2)k17039
(BDGP Project Members, 1994-1999)
lace
(Ashburner et al., 1990)
mRpL4
(Ashburner et al., 1990)
ms(2)35Eb
(Ashburner et al., 1990)
nAcRα-30D
(Watson et al., 2010)
ncm
(Marygold, 2005.1.19, Coelho et al., 2005)
rd
(Ashburner et al., 1990)
RpS26
(Marygold, 2005.1.19, Rizki et al., 1985, BDGP Project Members, 1994-1999, Spradling et al., 1999)
sna
(Ashburner et al., 1990)
stc
(Ashburner et al., 1990)
Su(H)
(Ashburner et al., 1990)
Syx5
(Ashburner et al., 1990)
TfIIS
(Ashburner et al., 1990)
vas
(Ashburner et al., 1990)
wek
(Ashburner et al., 1990)
wor
(Ashburner et al., 1990)
Molecular Data
bsf
(Marygold, 2005.1.19)
CG10176
(Marygold, 2005.1.19)
CG10178
(Marygold, 2005.1.19)
CG10211
(Marygold, 2005.1.19)
CG10283
(Marygold, 2005.1.19)
CG31749
(Marygold, 2005.1.19)
kon
(Marygold, 2005.1.19)
ncm
(Marygold, 2005.1.19)
Pde11
(Marygold, 2005.1.19)
RpS26
(Marygold, 2005.1.19)
hide Genes Duplicated
Complementation Data
Molecular Data
hide Genes NOT Duplicated
Complementation Data
Molecular Data
hide Related Comments
hide Phenotypic Data
In combination with other aberrations
Df(2L)M36F-S6 is semi-lethal in combination with Df(2L)H20. Surviving males and females are fertile.
(Levine et al., 2007)
Df(2L)RA5/Df(2L)H20 females have reduced fertility.
(Levine et al., 2007)
Df(2L)r10/Df(2L)H20 results in almost complete lethality.
(Levine et al., 2007)
Inferred to overlap with: Df(2L)TW137.
(Marygold, 2005.1.19)
Effect on variegation of y in In(1)y3P and Sb in T(2;3)SbV studied: inactivation of y occurs independently of inactivation of Sb.
(Bishop, 1992)
Enhancer of In(1)wm4h position-effect variegation.
(Wustmann et al., 1989)
Df(2L)H20/Df(2L)TW119 lethal Df(2L)H20/Df(2L)M36F-S5 lethal Df(2L)H20/Df(2L)TW137 lethal Df(2L)H20/Df(2L)T317 lethal Df(2L)H20/Df(2L)TW201 lethal Df(2L)H20/Df(2L)203 lethal Df(2L)H20/Df(2L)330 lethal Df(2L)H20/Df(2L)VA18 lethal
 
NOT in combination with other aberrations
Lysates from 4 hour old prepupae heterozygous for Df(2L)H20 show no reduction in caspase activation compared to wild type.
(Dorstyn et al., 2004)
The Df(2L)H20 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion).
(Mason et al., 2004)
Heterozygosity for Df(2L)H20 results in 2.8% X chromosome nondisjunction and 0.0% fourth chromosome nondisjunction in In(1)FM7/X ; svspa-pol females.
(Harris et al., 2003)
Heterozygotes show no adult central brain defect.
(Boquet et al., 2000)
Df(2L)H20 in combination with a pair of introgressions from D.simulans spanning 30F1-31E7 to 35D7-36A14 Dsim\Int(2L)S and 21A1 to 22D1--23A2 Dsim\Int(2L)D produces sterile male flies. These flies are female sterile.
(Sawamura et al., 2000)
Heterozygotes are flightless, but show normal muscle patterns, except for a reduced birefringence of the indirect flight muscles compared to those of wild type.
(Nongthomba and Ramachandra, 1999)
Does not cause unconditional lethality in hybrid females when heterozygous with D.simulans chromosome.
(Coyne et al., 1998)
Intermediate second site non-complementing phenotype with zipEbr and zipmhc-c6.1: malformed phenotype penetrance 25-75%.
(Halsell and Kiehart, 1998)
Shows no maternal enhancement of dpphr4.
(Nicholls and Gelbart, 1998)
Dominantly causes tergite defects in less than 50% of run3 heterozygotes.
(Duffy et al., 1996)
Midgut development of mutant embryos is wild type.
(Bilder and Scott, 1995)
Homozygous embryos have a truncated head and the stomodeum is shifted anteriorly.
(Harbecke and Lengyel, 1995)
Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovoD2.
(Pauli et al., 1995)
Nonmotile germ cells.
(Warrior, 1994)
hide Stocks ( 3 )
Bloomington
3180
Df(2L)H20, b1 pr1 cn1 sca1/CyO
Kyoto
106898
Df(2L)H20, b1 pr1 cn1 sca1/CyO
103256
CyO, Cy1 dplv1 pr1 cn2 / Df(2L)H20, b1 pr1 cn1 sca1
hide Notes on Origin
Discoverer
Nusslein-Volhard.
 
C. Nusslein-Volhard.
(Simpson, 1983)
hide Balancer / Genotype Variants of the Aberration
hide Separable Components
hide Other Comments
hide Synonyms & Secondary IDs ( 12 )
Reported As
Symbol Synonym
DcasDf(2L)H20
(Ratan et al., 2008)
Df(2)H20
(Nongthomba et al., 2003, Kronert et al., 1999)
Df(2L)dl2034
 
Df(2L)dlH20
(Simpson, 1983)
Df(2L)dl-H20
 
Df(2L)H2
(Duffy et al., 1996, Bilder and Scott, 1995, Watson et al., 2010)
Df(2L)H20
(Jordan et al., 2006, Marygold, 2005.1.19, Dorstyn et al., 2004, Crest et al., 2007, Minidorff et al., 2007, Ratan et al., 2008, McGraw et al., 2008, Rickmyre et al., 2007, Barbash and Lorigan, 2007, Pane et al., 2007, Morris et al., 2006, Levine et al., 2007, Babu and Ramachandra, 2007)
Df(2L) H20
(Dorstyn et al., 2004)
Df(2L)H20(d12034)
(Harris et al., 2003)
Df(2L)H2O
(Chapman et al., 2000)
Df(Δdc3/dc4)
(Dorstyn et al., 2004)
H20
(Hirose et al., 2001, Rizki et al., 1985)
Name Synonym
Secondary FlyBase IDs
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