FB2025_01 , released February 20, 2025
Aberration: Dmel\Df(2L)J39
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General Information
Symbol
Df(2L)J39
Species
D. melanogaster
Name
Deficiency (2L) Jammed
FlyBase ID
FBab0001478
Feature type
chromosomal_deletion
Computed Breakpoints include

31C;32D1-32E5

Features within 31C--32E5
Genomic Maps
Sequence coordinates
2L:10,247,078..10,272,324 (Df(2L)J39:bk1)
(Cook, 2016.2.8)
2L:11,013,206..11,169,361 (Df(2L)J39:bk2)
(Cook, 2016.2.8)
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
J1
Mutagen
X ray
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Schmidt et al., 1996, Kania et al., 1995, Clegg et al., 1993, Sinclair et al., 1992)
Breakpoints

31C-31D;32D-32E

(Sinclair et al., 1992)

31D;32B

(Clegg et al., 1993)

31A-31B;32D-32E

(Schmidt et al., 1996, Kania et al., 1995)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

chico << bk1 << M(2)31A << RpL9 << bk2

Genetic mapping information
Comments

The 2L:10247078..10272324 release 6 coordinates of the left breakpoint are estimates. The left extent corresponds to the right end of chico, which published results say is not deleted. The right extent corresponds to the right end of trk, which published results say is deleted.

(Cook, 2016.2.8)

The 2L:11013206..11169361 release 6 coordinates of the right breakpoint are estimates. The left extent corresponds to the left end of Samuel, which published results say is deleted. The right extent corresponds to the estimated position of the left end of band 32E1, because it is likely the breakpoint was seen to lie to the left of the 32E1,2 doublet band in reported polytene chromosome analyses.

(Cook, 2016.2.8)

This deletion removes multiple ribosomal protein-coding genes (in addition to other genes).

(Marygold et al., 2007)
Comments on Cytology

Ref: Lindsley and Zimm, 1992

(Kania et al., 1995)

Ref: Mange and Sandler, 1973, Genetics 73: 73--86

(Clegg et al., 1993)

Left limit of break 1 from polytene analysis (FBrf0056214) Right limit of break 1 from inclusion of l(2)31Bb (FBrf0058585) Left limit of break 2 from inclusion of RpL9 (FBrf0088926) Right limit of break 2 from polytene analysis (FBrf0056214)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
ao
(Sinclair et al., 1992)
aurB
(Wides et al., 1998)
bsk
(Clegg et al., 1993)
Cdk1
(Clegg et al., 1993)
da
(Clegg et al., 1993, Sinclair et al., 1992, Cronmiller and Cline, 1986)
dal
(Sinclair et al., 1992)
erratic
(Clegg et al., 1993)
Fkbp59
(Kania et al., 1995, BDGP Project Members, 1994-1999)
fs(2)ltoDG25
(Clegg et al., 1993)
fs(2)ltoPI23
(Clegg et al., 1993)
fs(2)ltoRU26
(Clegg et al., 1993)
Grip75
(Schnorrer et al., 2002)
hup
(Sinclair et al., 1992)
KdelR
(Clegg et al., 1993)
l(2)31Bb
(Clegg et al., 1993)
l(2)31Bc
(Clegg et al., 1993)
l(2)31Ca
(Clegg et al., 1993)
l(2)31Cb
(Clegg et al., 1993)
l(2)31Da
(Clegg et al., 1993)
l(2)31Db
(Clegg et al., 1993)
l(2)31Eb
(Clegg et al., 1993)
l(2)31Ec
(Clegg et al., 1993)
l(2)31Ed
(Clegg et al., 1993)
l(2)31Ee
(Clegg et al., 1993)
l(2)31Ef
(Clegg et al., 1993)
l(2)31Eg
(Clegg et al., 1993)
l(2)31Ej
(Clegg et al., 1993)
l(2)31En
(Clegg et al., 1993)
l(2)31Eo
(Clegg et al., 1993)
l(2)31Ep
(Clegg et al., 1993)
l(2)31Eq
(Clegg et al., 1993)
l(2)31Er
(Clegg et al., 1993)
l(2)31Es
(Clegg et al., 1993)
l(2)31Et
(Clegg et al., 1993)
l(2)31Eu
(Clegg et al., 1993)
l(2)31Fa
(Clegg et al., 1993)
l(2)32Aa
(Clegg et al., 1993)
l(2)32Ab
(Clegg et al., 1993)
l(2)32Ac
(Clegg et al., 1993)
l(2)32Ad
(Clegg et al., 1993)
l(2)32Ae
(Clegg et al., 1993)
l(2)32Af
(Clegg et al., 1993)
M(2)31A
(Schmidt et al., 1996)
mat(2)syn-E
(Kahsai and Cook, 2018, Clegg et al., 1993)
Nup154
(Kiger et al., 1999, Schmidt et al., 1996)
obx
(Kania et al., 1995, BDGP Project Members, 1994-1999)
pie
(Shi et al., 2003, Clegg et al., 1993, Sinclair et al., 1992)
pim
(Clegg et al., 1993)
RpL9
(Schmidt et al., 1996)
RpS27A
(Clegg et al., 1993, Sinclair et al., 1992)
SamDC
(Clegg et al., 1993)
Samuel
(Baker et al., 2007)
trk
(Clegg et al., 1993)
wdl
(Clegg et al., 1993, Sinclair et al., 1992)
Partially deleted / disrupted
Molecular Data
Completely deleted
mRpS7
(Marygold et al., 2007)
RpL9
(Marygold et al., 2007)
RpS27A
(Marygold et al., 2007)
Partially deleted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (216)
Phenotypic Data
In combination with other aberrations

Df(2L)J39/+ heterozygote showed slight suppression of In(1)wm4 variegation.

(Sinclair et al., 1992)
NOT in combination with other aberrations

Flies heterozygous for the deletion show a Minute bristle phenotype.

(Marygold et al., 2007)

Df(2L)J39 in combination with a pair of introgressions from D.simulans spanning 30F1-31E7 to 35D7-36A14 Dsim\Int(2L)S and 21A1 to 22D1--23A2 Dsim\Int(2L)D produces sterile male flies. These flies are female sterile.

(Sawamura et al., 2000)

Does not cause unconditional lethality in hybrid females when heterozygous with D.simulans chromosome.

(Coyne et al., 1998)

Weak second site non-complementing phenotype with zipEbr and zipmhc-c6.1 : malformed phenotype penetrance 10-24%.

(Halsell and Kiehart, 1998)

Deficient embryos show an uninterpretable mutant midgut phenotype.

(Bilder and Scott, 1995)

Dominant female sterile Minute phenotype.

(Cronmiller and Cline, 1986)
Stocks (2)
Notes on Origin
Discoverer
 

Revertant

Balancer / Genotype Variants of the Aberration
 
Separable Components
 
Other Comments
 

The Df(2L)J39 chromosome contains a lesion in the 21A region, in addition to the deficiency at 31D1-32E5.

(Brumby et al., 2004)

"31C--D;32D--E" was stated as revision.

(Sinclair et al., 1992)
Synonyms and Secondary IDs (7)
Reported As
Symbol Synonym
Df(2L)J39
(Muraoka et al., 2018)
Df(2L)J-der-39
(Cronmiller and Cline, 1986)
Df(2L)J-der39
Df(2L)J-rv39
Df(2L)J39
(Li et al., 2020, Sawyer et al., 2020, Lopez-Gonzalez et al., 2019, Kahsai and Cook, 2018, Anderson et al., 2017, Talsma et al., 2014, Watson et al., 2010, Baker et al., 2007)
Df39
(Sinclair et al., 1992)
Name Synonyms
Deficiency (2L) Jammed
Secondary FlyBase IDs
    References (37)