FB2025_01 , released February 20, 2025
Aberration: Dmel\Df(2L)Mdh
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General Information
Symbol
Df(2L)Mdh
Species
D. melanogaster
Name
Deficiency (2L) Malate dehydrogenase
FlyBase ID
FBab0001497
Feature type
chromosomal_deletion
Also Known As
Df(2L)MdhA
Computed Breakpoints include

30D-30F;31F

Features within 30D--31F
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
J1
Mutagen
X ray
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Kania et al., 1995)
Breakpoints

30D-30F;31F

(Kania et al., 1995)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

hoip << bk1 << J << da << bk2 << hup

Genetic mapping information
Comments
Comments on Cytology

Ref: Lindsley and Zimm, 1992

(Kania et al., 1995)

All limits from polytene analysis (FBrf0080145)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
E(Mer)IIb
(LaJeunesse et al., 2001)
ifm(2)RS2
(Babu and Ramachandra, 2007)
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
    In these cases, there will be no "Export to Hitlist" button to the left.
    Phenotypic Data
    In combination with other aberrations
    NOT in combination with other aberrations

    The Df(2L)Mdh chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion).

    (Mason et al., 2004)

    Df(2L)Mdh in combination with a pair of introgressions from D.simulans spanning 30F1-31E7 to 35D7-36A14 Dsim\Int(2L)S and 21A1 to 22D1--23A2 Dsim\Int(2L)D produces fertile male flies. These flies are female sterile.

    (Sawamura et al., 2000)

    Shows dominant enhancement of dominant haltere phenotype caused by Ubx195 and Ubx9.22.

    (Burnette et al., 1999)

    No second site non-complementing phenotype with zipEbr and zipmhc-c6.1.

    (Halsell and Kiehart, 1998)

    Deficient embryos show an uninterpretable mutant midgut phenotype.

    (Bilder and Scott, 1995)
    Stocks (3)
    Notes on Origin
    Discoverer
     

    Revertant

    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (5)
    Reported As
    Symbol Synonym
    Df(2L)Mdh
    (Muraoka et al., 2018)
    Df(2L)Mdh
    (Ribot et al., 2022, Marcogliese et al., 2017, Fernandes and Rao, 2011, Watson et al., 2010, Babu and Ramachandra, 2007)
    Df(2L)Mdh-2J
    Df(2L)MdhA
    (Gildea et al., 2000, Bilder and Scott, 1995)
    Name Synonyms
    Deficiency (2L) Malate dehydrogenase
    Secondary FlyBase IDs
      References (24)