Aberration Dmel\Df(2L)N22-5

General Information
Symbol	Dmel\Df(2L)N22-5	Species	D. melanogaster
Name		FlyBase ID	FBab0001500
Feature type	chromosomal_deletion

Computed Breakpoints include	29C3-29C5;30C8-30C9
Deleted segment	29C3--30C9
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor	P{en-lacZ(wXba)}9 (Neuman-Silberberg and Schupbach, 1993)
Mutagen	gamma ray (Neuman-Silberberg and Schupbach, 1993)
Class of aberration (relative to progenitor)	chromosomal_deletion (Neuman-Silberberg and Schupbach, 1993, Ashburner, 1992.5.27, Collier and Gubb, 1997, Wustmann et al., 1989)
Breakpoints	29C3--5;[] (Neuman-Silberberg and Schupbach, 1993) 29C3-29C5;30C8-30C9 (Ashburner, 1992.5.27, Collier and Gubb, 1997) 29D1-29D2;30C4-30D1 (Wustmann et al., 1989)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	fy << bk1 << l(2)DB2 << bk2
Genetic mapping information
Comments
Comments on Cytology
	Limits of break 1 from polytene analysis (FBrf0065509) Limits of break 2 from polytene analysis (FBrf0089969)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	aust (Gao et al., 2008) d (Thibault et al., 2004, Mao et al., 2006) hoip (Spradling et al., 1999, BDGP Project Members, 1994-1999) huc29DE (Silva et al., 2006) l(2)DB2 (Spradling et al., 1999, Cook, 2002.3.7, BDGP Project Members, 1994-1999, Beaton, 1997.3.4) l(2)k04003 (Spradling et al., 1999, BDGP Project Members, 1994-1999) l(2)k05125a (Spradling et al., 1999, BDGP Project Members, 1994-1999) l(2)rH280 (Spradling et al., 1999, BDGP Project Members, 1994-1999) l(2)s2978 (Spradling et al., 1999) lmgA (BDGP Project Members, 1994-1999) nAcRα-30D (Watson et al., 2010) Orct (Spradling et al., 1999) raw (Spradling et al., 1999, Byars et al., 1999, BDGP Project Members, 1994-1999) Sema-1a (Yu et al., 1998, Spradling et al., 1999, BDGP Project Members, 1994-1999, Yu et al., 2010) SoxN (Overton et al., 2002) tai (Spradling et al., 1999, BDGP Project Members, 1994-1999) zf30C (Cook, 2002.3.7)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	Acer (Spradling et al., 1999, BDGP Project Members, 1994-1999) emb (Spradling et al., 1999, BDGP Project Members, 1994-1999) FKBP59 (Spradling et al., 1999, BDGP Project Members, 1994-1999) fy (Ashburner, 1992.5.27, Collier and Gubb, 1997) grk (Neuman-Silberberg and Schupbach, 1993) l(2)01482 (Spradling et al., 1999, BDGP Project Members, 1994-1999) l(2)k01006 (BDGP Project Members, 1994-1999) l(2)k03706 (BDGP Project Members, 1994-1999) l(2)k12408 (BDGP Project Members, 1994-1999) l(2)k12914 (Spradling et al., 1999, BDGP Project Members, 1994-1999) l(2)k14204 (Spradling et al., 1999, BDGP Project Members, 1994-1999) l(2)k15306 (BDGP Project Members, 1994-1999) l(2)s2978 (BDGP Project Members, 1994-1999) mus201 (Sekelsky et al., 2000) RpS13 (Spradling et al., 1999, BDGP Project Members, 1994-1999) snRNA:U6atac:29B (Spradling et al., 1999, BDGP Project Members, 1994-1999)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations	No effect on In(1)w^m4h position-effect variegation. (Wustmann et al., 1989)
NOT in combination with other aberrations	The Df(2L)N22-5 chromosome acts as a dominant weak suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion). (Mason et al., 2004) Heterozygosity for Df(2L)N22-5 results in 0.4% X chromosome nondisjunction and 0.0% fourth chromosome nondisjunction in In(1)FM7/X ; sv^spa-pol females. (Harris et al., 2003)
Stocks ( 2 )
Bloomington	384 w^*; Df(2L)N22-5/CyO
Kyoto	105882 w^*; Df(2L)N22-5/CyO
Notes on Origin
Discoverer	Schupbach.

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments
	Deletes in a proximal direction from stated breakpoint. Cytology of second break not reported. (Neuman-Silberberg and Schupbach, 1993) "29C3--5;30C8--9" was stated as revision. (Ashburner, 1992.5.27)
Synonyms & Secondary IDs ( 6 )
Reported As
Symbol Synonym	Df(2)N22--5 (Cafferty et al., 2006) Df(2L)N22-5 (Mao et al., 2006, Gao et al., 2008, Casso et al., 2008, Tanaka and Nakamura, 2008, Silva et al., 2006, Watson et al., 2010) DfN-22 (Buescher et al., 2002) N22-5 (Yamaguchi et al., 2001) sema1a^Df(2)N22-5 (Yu et al., 2010) Sema1a^Df(2L)N22-5 (Miller et al., 2011)
Name Synonym
Secondary FlyBase IDs

References ( 30 )

Generate a list of	All references relating to this aberration ( 30 )

List References by type	Research paper ( 23 ) Personal communication to FlyBase ( 4 ) Abstract ( 1 ) FlyBase analysis ( 1 ) Book ( 1 )
Recent research papers ( 1 )
	Miller et al., 2011, J. Neurosci. 31(14): 5335--5347 Drosophila mmp2 regulates the matrix molecule faulty attraction (frac) to promote motor axon targeting in Drosophila. [FBrf0213409] Show all research papers ...