Aberration Dmel\Df(2L)PM44

General Information
Symbol	Dmel\Df(2L)PM44	Species	D. melanogaster
Name		FlyBase ID	FBab0001513
Feature type	chromosomal_deletion

Computed Breakpoints include	21A1;21B2-21B4
Deleted segment	21A1--21B4
Sequence coordinates
Recent Updates
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FB2012_01
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Aberration
Cytological Order
Progenitor
Mutagen
Class of aberration (relative to progenitor)	chromosomal_deletion
Breakpoints
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	bk1 << l(2)gl << l(2)21Ba1 << bk2 << Gs1
Genetic mapping information
Comments
Comments on Cytology
	All limits from polytene analysis (citation unavailable)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	l(2)21Ba1 (Caggese et al., 1994) l(2)gl (Caggese et al., 1994, Larsson et al., 1996) net (Caggese et al., 1988, Caggese et al., 1994) Sam-S (Larsson et al., 1995, Larsson et al., 1996)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	al (Caggese et al., 1988, Caggese et al., 1994) Gs1 (Caggese et al., 1988, Caggese et al., 1994, Larsson et al., 1996) l(2)21Ba (Caggese et al., 1988, Caggese et al., 1994, Larsson et al., 1996) l(2)21Bb (Caggese et al., 1988, Caggese et al., 1994, Larsson et al., 1996) l(2)21Bd (Caggese et al., 1988, Caggese et al., 1994) l(2)21Be (Caggese et al., 1994)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	Homozygotes die during the late embryonic and first larval instar stages. (Larsson and Rasmuson-Lestander, 1998) Fails to suppress z¹ w^is and In(1)w^m4 mutant phenotypes and weakly enhances Pc¹¹. (Larsson et al., 1996)
Stocks ( 2 )
Bloomington	6132 Df(2L)PM44/SM6a
Kyoto	108632 Df(2L)PM44/SM6a
Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	Df(2)PM44 (Larssen et al., 1994) Df(2L)PM44 DfnetPM44 (Caggese et al., 1994)
Name Synonym
Secondary FlyBase IDs

References ( 9 )
Research paper	Dai et al., 2003, Dev. Cell 4(6): 917--928 A hedgehog-responsive region in the Drosophila wing disc is defined by debra-mediated ubiquitination and lysosomal degradation of Ci. [FBrf0160468] Larsson and Rasmuson-Lestander, 1998, FEBS Lett. 427(1): 119--123 Somatic and germline clone analysis in mutants of the S-adenosylmethionine synthetase encoding gene in Drosophila melanogaster. [FBrf0102516] Larsson et al., 1996, Genetics 143(2): 887--896 Mutations in the Drosophila melanogaster gene encoding S-adenosylmethionine synthetase suppress position-effect variegation. [FBrf0087538] Caggese et al., 1988, Biochem. Genet. 26(9--10): 571--584 Genetic determinants of glutamine synthetase in Drosophila melanogaster: a gene for glutamine synthetase I resides in the 21B3-6 region. [FBrf0047556]
Review	Caggese et al., 1994, Genetica 94(2-3): 275--281 Genetic, molecular and developmental analysis of the glutamine synthetase isozymes of Drosophila melanogaster. [FBrf0079921]
Abstract	Larsson et al., 1995, Europ. Dros. Res. Conf. 14: 144 Genetical and molecular analysis of the Su(z)5 gene in Drosophila melanogaster. [FBrf0083251] Larssen et al., 1994, Hereditas 121(3): 209 Genetical and molecular analysis of the Su(z)5 gene in Drosophila melanogaster. [FBrf0095545]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]
Book	Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster. The Genome of Drosophila melanogaster. [FBrf0066905]