FlyBase Aberration Report: Dmel\Df(2L)RA5

General Information

Symbol

Df(2L)RA5

Species

D. melanogaster

Name

FlyBase ID

FBab0001523

Feature type

chromosomal_deletion

Also Known As

BicC^Δ

Computed Breakpoints include

35E1;35F11-36A1

Features within 35E1--36A1

Sequence coordinates

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

Progenitor

P{FZ}cact²⁵⁵

(Landis and Tower, 1999)

cact^E10

(Roote, 1996.8)

Mutagen

irradiation

(Roote, 1996.8)

Class of aberration (relative to wild type)

chromosomal_deletion

(FlyBase, 2007)

Class of aberration (relative to progenitor)

chromosomal_deletion

Breakpoints

Causes alleles

Carries alleles

Transposon Insertions

Formalized genetic data

l(2)35De << bk1 << fs(2)35Ec << l(2)35Fg << bk2 << dac

Genetic mapping information

Comments

This deletion removes a single ribosomal protein-coding gene (though other genes are also removed).

(Marygold et al., 2007)

Comments on Cytology

Left limit of break 1 from polytene analysis (citation unavailable) Right limit of break 1 from inclusion of ms(2)35Eb (FBrf0051973) Left limit of break 2 from inclusion of mRpL4 (FBrf0051973) Right limit of break 2 from non-inclusion of dac (FBrf0051973)

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

BicC

(Eberl et al., 1998, Mahone et al., 1995, Ashburner et al., 1990)

cact

(Levine et al., 2007, Eberl et al., 1998, Ashburner et al., 1990)

Ca-α1D

(Eberl et al., 1998, Mahone et al., 1995, Ashburner et al., 1990)

chif

(Levine et al., 2007, Eberl et al., 1998, Roote, 1996.8, Ashburner et al., 1990)

cni

(Eberl et al., 1998, Ashburner et al., 1990)

crp

(Eberl et al., 1998)

Cyp303a1

(Eberl et al., 1998, Ashburner et al., 1990)

EndoGI

(Temme et al., 2009)

fs(2)35Ec

(Roote, 1997.6.6)

fzy

(Eberl et al., 1998, Ashburner et al., 1990)

heix

(Eberl et al., 1998, Ashburner et al., 1990)

l(2)35Fg

(Roote, 2010.1.4, Levine et al., 2007, Roote, 1996.8, BDGP Project Members, 1994-1999)

mRpL4

(Levine et al., 2007, Eberl et al., 1998, Roote, 1996.8, Ashburner et al., 1990)

ms(2)35Eb

(Eberl et al., 1998, Roote, 1996.8, Mahone et al., 1995, Ashburner et al., 1990)

Syx5

(Eberl et al., 1998, Ashburner et al., 1990)

twe

(Eberl et al., 1998)

Partially deleted / disrupted

Molecular Data

Completely deleted

mRpL4

(Marygold et al., 2007)

Partially deleted

Genes NOT Deleted / Disrupted

Complementation Data

(Ashburner et al., 1990)

crp

(Ashburner et al., 1990)

Cul3

(Ashburner et al., 1990)

CycE

(Ashburner et al., 1990)

dac

(Roote, 1996.8, Ashburner et al., 1990)

esg

(Ashburner et al., 1990)

Gli

(Ashburner et al., 1990)

l(2)35De

(Roote, 1996.8, Ashburner et al., 1990)

l(2)36Aa

(Ashburner et al., 1990)

l(2)36Ab

(Ashburner et al., 1990)

l(2)36Ac

(Ashburner et al., 1990)

l(2)36Ad

(Ashburner et al., 1990)

lace

(Ashburner et al., 1990)

Mtr4

(Ashburner et al., 1990)

ND-B17

(Ashburner et al., 1990)

plo

(Ashburner et al., 1990)

PolD3

(Ashburner et al., 1990)

sna

(Ashburner et al., 1990)

stc

(Ashburner et al., 1990)

Su(H)

(Ashburner et al., 1990)

TfIIS

(Ashburner et al., 1990)

Uxt

(Ashburner et al., 1990)

vas

(Ashburner et al., 1990)

wek

(Roote, 1996.8, Ashburner et al., 1990)

wor

(Ashburner et al., 1990)

Molecular Data

Genes Duplicated

Complementation Data

Completely duplicated

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Affected Genes Inferred by Location (0)

If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
In these cases, there will be no "Export to Hitlist" button to the left.

Related Comments

Phenotypic Data

In combination with other aberrations

Df(2L)MN-I/Df(2L)RA5 animals are fertile.

(Levine et al., 2007)

Df(2L)RA5/Df(2L)H20 females have reduced fertility.

(Levine et al., 2007)

Female sterile in combination with Df(2L)TE35D-3. Male sterile in combination with Df(2L)TE35D-14. Viable in combination with Df(2L)TE35D-19.

(Ashburner et al., 1999)

Heterozygotes with Df(2L)el28, Df(2L)TE35B-2, In(2L)TE35B-13, Df(2L)Sco^rv10, Df(2L)Sco^rv14, Df(2L)TE35D-24, Df(2L)A246, In(2LR)pkD1-rv2, In(2LR)pkD1-rv3 or Df(2L)Adh-nBR120 exhibit a leaky female sterile phenotype (uncovering fs(2)35Ec). Heterozygotes with Df(2L)Sco7, Df(2L)TE35BC-8, Df(2L)TE35D-3, Df(2L)TE35D-11, Df(2L)TE35D-17, Df(2L)TE35D-5, Df(2L)TE35D-12 or In(2LR)noc^4LD6^R are completely female sterile (uncovering fs(2)35Ec).

(Roote, 1997.6.6)

NOT in combination with other aberrations

Flies heterozygous for the deletion do not show a Minute bristle phenotype.

(Marygold et al., 2007)

Most eggs laid develop to hatched larvae, some are undeveloped due to a developmental block in the later syncytial divisions.

(Mahone et al., 1995)

Stocks (2)

Bloomington

6915

Df(2L)RA5/CyO

Kyoto

101430

Df(2L)RA5, speck¹ / CyO

Notes on Origin

Discoverer

Y. Hiromi.

(Roote, 1996.8)

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

BicC^Δ

(Millet-Boureima et al., 2019, Gamberi et al., 2017)

Chif^RA5

(Cayirlioglu et al., 2003)

Df(2L)RA5

(Millet-Boureima et al., 2020, Millet-Boureima et al., 2019, Torres-Zelada et al., 2019, Dragh et al., 2017, Gamberi et al., 2017, Xia et al., 2015, O'Keefe et al., 2011, Gamberi, 2010.7.23, Roote, 2010.1.4, Temme et al., 2009, Von Stetina et al., 2008, Levine et al., 2007)

dfRA5

(Tower, 1999.12.23)

Name Synonyms

Secondary FlyBase IDs

References (27)

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