FB2025_01 , released February 20, 2025
Aberration: Dmel\Df(2L)RF
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General Information
Symbol
Df(2L)RF
Species
D. melanogaster
Name
FlyBase ID
FBab0001524
Feature type
chromosomal_deletion
Also Known As
wgRF
Computed Breakpoints include

27E3-27F2;28B3-28B4

Features within 27E3--28B4
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
gamma ray
(Tiong and Nash, 1990)
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Buratovich et al., 1997, Tiong and Nash, 1990)
Breakpoints

27E3-27F;28B3-28B4

(Tiong and Nash, 1990)

27E-27F;28B3-28B4

(Buratovich et al., 1997)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

l(2)27Ea << bk1 << wg << l(2)28Aa << bk2 << l(2)28Bc

Genetic mapping information
Comments
Comments on Cytology

Left limit of break 1 from polytene analysis (FBrf0051986) Right limit of break 1 from inclusion of wg (FBrf0051986) Limits of break 2 from polytene analysis (FBrf0051986)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
l(2)28Aa
(Tiong and Nash, 1990)
l(2)28Ab
(Tiong and Nash, 1990)
l(2)28Ac
(Tiong and Nash, 1990)
wg
(Buratovich et al., 1997, Tiong and Nash, 1990)
Wnt4
(Cohen et al., 2002)
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
    In these cases, there will be no "Export to Hitlist" button to the left.
    Phenotypic Data
    In combination with other aberrations
    NOT in combination with other aberrations

    Df(2L)RF clones at the edge of the eye result in ectopic interommatidial bristles forming up to the edge of the eye in 1/3 of cases.

    (Cadigan et al., 2002)

    When Pka-C1E95, Df(2L)RF (which removes the genes Wnt4, Wnt6 and Wnt10) homozygous clones are made in the adult abdomen, the polarity os reversed in the same way as Pka-C1E95 clones are.

    (Lawrence et al., 2002)

    Homozygotes show a severe P{en1}wgen11 phenotype. Transheterozygotes with wgspd-fg exhibit a markedly etched wing margin. When in combination with wgspd-fg homozygotes the level of wing etching is also increased (compared to wgspd-fg homozygotes).

    (Buratovich et al., 1997)
    Stocks (1)
    Notes on Origin
    Discoverer
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     

    Also deletes Sternopleural.

    (Buratovich et al., 1997)
    Synonyms and Secondary IDs (2)
    Reported As
    Symbol Synonym
    Df(2L)RF
    (Casso et al., 2008, Joshi et al., 2007)
    wgRF
    (Hatori et al., 2021, Mottier-Pavie et al., 2016)
    Name Synonyms
    Secondary FlyBase IDs
      References (12)