Open Close
General Information
Symbol
Df(2L)S2
Species
D. melanogaster
Name
Deficiency (2L) Star
FlyBase ID
FBab0001537
Feature type
Also Known As
Df(2L)S2
Computed Breakpoints include

21C8-21D1;22A8-22B1

Deleted Segment
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Class of aberration (relative to wild type)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

Gsc << bk1 << lea << bk2 << Got2

Genetic mapping information
Comments
Comments on Cytology

Ref: Lindsley and Zimm, 1992

Left break appears to be just left of 21D1-21D2, right break appears to be just before 22B1-22B2, although the breaks may be in the middle of these two doublets.

Left limit of break 1 from polytene analysis (FBrf0006343) Right limit of break 1 from polytene analysis (FBrf0042627) Left limit of break 2 from polytene analysis (FBrf0006343) Right limit of break 2 from polytene analysis (FBrf0042627)

Sequence Crossreferences
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Phenotypic Data
In combination with other aberrations

No effect on In(1)wm4h position-effect variegation.

NOT in combination with other aberrations

Heterozygosity for Df(2L)S2 results in 0.3% X chromosome nondisjunction and 0.5% fourth chromosome nondisjunction in In(1)FM7/X ; svspa-pol females.

Dominantly causes tergite defects in less than 50% of run3 heterozygotes.

Deficient embryos show a variably penetrant mutant midgut phenotype: incomplete constriction formation.

Homozygous embryos have head defects and tracheae are disconnected.

Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovoD2.

Stocks (1)
Notes on Origin
Discoverer

E.B. Lewis, 1940.

 
Balancer / Genotype Variants of the Aberration
 
Separable Components
 
Other Comments
 

The Df(2L)S2 chromosome acts as a dominant moderate suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion), but this is assumed to be a false positive result (the suppressor may not be within the bounds of the deficient region) because the 2L TAS array on the chromosome is reduced (as assayed by in situ hybridization) and it has previously been shown (FBrf0137248, FBrf0158986) that partial or complete deficiency of the 2L TAS array on the homologue suppresses silencing of brown-red variants of P{3'WP-2,wvar}2Lt.

Synonyms and Secondary IDs (8)
Reported As
Name Synonyms
Deficiency (2L) Star
Secondary FlyBase IDs
    References (34)