FB2025_01 , released February 20, 2025
Aberration: Dmel\Df(2L)S3
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General Information
Symbol
Df(2L)S3
Species
D. melanogaster
Name
Deficiency (2L) Star
FlyBase ID
FBab0001538
Feature type
chromosomal_deletion
Also Known As
Df(2L)S3, S3
Computed Breakpoints include

21D2;21F3-22A1

Features within 21D2--22A1
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
X ray
(Higson et al., 1993, Roberts et al., 1985, Lewis, 1945)
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Adler et al., 1998, Kotarski et al., 1998, Pauli et al., 1995, Higson et al., 1993, de Belle et al., 1989, Caggese et al., 1988, Roberts et al., 1985, Lewis, 1945)
Breakpoints

21D2-21D3;21F3-22A1

(Lewis, 1945)

21D2;21F3-22A1

(Roberts et al., 1985)

21D1-21D3;21F2-22A1

(Caggese et al., 1988)

21D2-21D3;21F2-22A1

(Kotarski et al., 1998, Pauli et al., 1995, Higson et al., 1993, de Belle et al., 1989)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

ex << bk1 << l(2)21Da << bk2 << shr

Genetic mapping information
Comments
Comments on Cytology

Ref: FBrf0006343.

(Kotarski et al., 1998)

Ref: Lewis, 1945, Genetics 30: 137--166

(Caggese et al., 1988)

Left break is just to the right of 21D1-21D2, right break is just before 22A1-22A2.

(Lewis, 1945)

Left limit of break 1 from polytene analysis (FBrf0006343) Right limit of break 1 from polytene analysis (FBrf0042627) Limits of break 2 from polytene analysis (FBrf0006343)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
ast
(Roberts et al., 1985, Lewis, 1945)
capt
(Benlali et al., 2000)
S
(Sapir et al., 1998, Dickson et al., 1996, Tearle and Nusslein-Volhard, 1987, Lewis, 1945)
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
    In these cases, there will be no "Export to Hitlist" button to the left.
    Phenotypic Data
    In combination with other aberrations

    No effect on In(1)wm4h position-effect variegation.

    (Wustmann et al., 1989)

    Lethal in combination with T(2;4)astv.

    (Lewis, 1945)
    NOT in combination with other aberrations

    Eye phenotype is dominantly enhanced by astK6.

    (Kotarski et al., 1998)

    Hemizygosity weakly enhances the phl::tor12D.hs.sev phenotype.

    (Dickson et al., 1996)

    Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovoD2.

    (Pauli et al., 1995)
    Stocks (5)
    Notes on Origin
    Discoverer

    E.B. Lewis, 1940.

     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     

    The Df(2L)S3 chromosome may act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion), but the eye colour phenotype in the presence of Df(2L)S3 overlaps the eye colour phenotype in a wild-type background so it cannot be unequivocally demonstrated that the deficiency chromosome uncovers a suppressor of telomeric silencing.

    (Mason et al., 2004)
    Synonyms and Secondary IDs (10)
    References (26)