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General Information
D. melanogaster
Deficiency (2L) Star
FlyBase ID
Feature type
Also Known As
Df(2L)S3, S3
Computed Breakpoints include
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Class of aberration (relative to wild type)




Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

ex << bk1 << l(2)21Da << bk2 << shr

Genetic mapping information
Comments on Cytology

Ref: Lewis, 1945, Genetics 30: 137--166

Left break is just to the right of 21D1-21D2, right break is just before 22A1-22A2.

Left limit of break 1 from polytene analysis (FBrf0006343) Right limit of break 1 from polytene analysis (FBrf0042627) Limits of break 2 from polytene analysis (FBrf0006343)

Sequence Crossreferences
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
Molecular Data
Affected Genes Inferred by Location
    Phenotypic Data
    In combination with other aberrations

    No effect on In(1)wm4h position-effect variegation.

    Lethal in combination with T(2;4)astv.

    NOT in combination with other aberrations

    Eye phenotype is dominantly enhanced by astK6.

    Hemizygosity weakly enhances the phl::tor12D.hs.sev phenotype.

    Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovoD2.

    Stocks (5)
    Notes on Origin

    E.B. Lewis, 1940.

    Balancer / Genotype Variants of the Aberration
    Separable Components
    Other Comments

    The Df(2L)S3 chromosome may act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion), but the eye colour phenotype in the presence of Df(2L)S3 overlaps the eye colour phenotype in a wild-type background so it cannot be unequivocally demonstrated that the deficiency chromosome uncovers a suppressor of telomeric silencing.

    Synonyms and Secondary IDs (10)
    References (26)