FB2022_02, released March 29, 2022

Aberration: Dmel\Df(2L)Sd37

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General Information
Symbol
Df(2L)Sd37
Species
D. melanogaster
Name
Deficiency (2L) Segregation distorter
FlyBase ID
FBab0001557
Feature type
chromosomal_deletion
Also Known As
SD-5R37
Computed Breakpoints include

37D2-37D5;38A6-38B2

Features within 37D2--38B2
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
X ray
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Stathakis et al., 1995, Pentz et al., 1990, Ganetzky, 1977)
Breakpoints

37D2-37D7;38A6-38B2

(Pentz et al., 1990, Ganetzky, 1977)

37C6-37D1;38A6-38B2

(Stathakis et al., 1995)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

γTub37C << bk1 << l(2)37Dd << l(2)37Fg << bk2 << pr

Genetic mapping information
Comments

Copy number variation (CNV) analysis identifies a deletion on chromosome 2L with breakpoints occurring in approximately 3kb windows whose midpoints are coordinates 2L:19423344 and 2L:19962150 .

(Daines et al., 2009)
Comments on Cytology

Ref: FBrf0030142.

(Stathakis et al., 1995)

Left limit of break 1 from polytene analysis (FBrf0030142) Right limit of break 1 from inclusion of RanGap (FBrf0030142) Limits of break 2 from polytene analysis (FBrf0030142)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location
    Phenotypic Data
    In combination with other aberrations

    Viable and female fertile in combination with Df(2L)be408. Viable and fertile in combination with Df(2L)pr2b. Viable and fertile in combination with Df(2L)pr37. Viable, male fertile and female subfertile in combination with Df(2L)pr11163. Viable and fertile in combination with Df(2L)pr-M1. Lethal in combination with Df(2L)pr49. Lethal in combination with Df(2L)pr8311. Lethal in combination with Df(2L)pr1122. Lethal in combination with Df(2L)TW1. Lethal in combination with Df(2L)TW161.

    (Butler et al., 2001)
    NOT in combination with other aberrations

    The Df(2L)Sd37 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion).

    (Mason et al., 2004)
    Stocks (2)
    Notes on Origin
    Discoverer
     

    Induced on: SD-5.

    (McLean et al., 1994, Temin, 1991)

    Induced: on SD-5.

    (Brittnacher and Ganetzky, 1984)

    Induced on: an SD-5 chromosome carrying In(2R)SD5 and In(2R)NS.

    (Ganetzky, 1977)

    Induced on: In(2R)NS, In(2R)SD5, SD-5.

    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     

    37C6-37D1 breakpoint is between position +60.1 and +66.8 on the Ddc map relative to the HpaI restriction site near the 3' end of Ddc.

    (Stathakis et al., 1995)
    Synonyms and Secondary IDs (5)
    Reported As
    Symbol Synonym
    Df(2L)Sd37
    (Daines et al., 2009, Casso et al., 2008)
    Df(2L)Sd37
    (Pentz et al., 1990)
    SD-5R37
    (McLean et al., 1994, Temin, 1991, Brittnacher and Ganetzky, 1984, Brittnacher and Ganetzky, 1983)
    SDRev-37
    (Ganetzky, 1977)
    Name Synonyms
    Deficiency (2L) Segregation distorter
    Secondary FlyBase IDs
      References (16)