Aberration Dmel\Df(2L)TE35BC-3

General Information
Symbol	Dmel\Df(2L)TE35BC-3	Species	D. melanogaster
Name		FlyBase ID	FBab0001609
Feature type	chromosomal_deletion
Also Known As	Df(2L)TE36-GC, Df(2L)TE36(R)GW3

Computed Breakpoints include	35B10;35D2
Deleted segment	35B10--35D2
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor	Tp(1;2)TE35BC (Ashburner, 1982, Gubb et al., 1984)
Mutagen	gamma ray (Ashburner, 1982, Gubb et al., 1984, Grau et al., 1984)
Class of aberration (relative to progenitor)	chromosomal_deletion (Gubb et al., 1990, Gubb et al., 1984, Grau et al., 1984)
Breakpoints	35B9-35B10;35D2 (Gubb et al., 1984) 35C1;35D2 (Gubb et al., 1990, Grau et al., 1984)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	Su(H) << bk1 << ck << lace << bk2 << CycE
Genetic mapping information
Comments
Comments on Cytology
	Ref: FBrf0039455. (Grau et al., 1984) Left limit of break 1 from non-inclusion of Su(H) (FBrf0038053) Right limit of break 1 from polytene analysis (FBrf0040529) Left limit of break 2 from inclusion of lace (FBrf0038047) Right limit of break 2 from polytene analysis (citation unavailable)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	BicC (Gubb et al., 1984, Grau et al., 1984) ck (Ashburner et al., 1982, Ashburner, 1982, Gubb et al., 1984, Ashburner et al., 1990, Grau et al., 1984) Cul-3 (Cai et al., 2001, Ashburner et al., 1982, Ashburner, 1982, Ashburner et al., 1990) esg (Cai et al., 2001, Ashburner et al., 1990) l(2)35Cc (Cai et al., 2001, Ashburner et al., 1990) l(2)35Cg (Cai et al., 2001) l(2)35Ch (Cai et al., 2001) lace (Ashburner et al., 1982, Ashburner, 1982, Gubb et al., 1984, Ashburner et al., 1990, Grau et al., 1984) rd (Ashburner et al., 1982, Ashburner, 1982, Gubb et al., 1984, Ashburner et al., 1990, Grau et al., 1984) sna (Cai et al., 2001, Ashburner et al., 1982, Ashburner, 1982, Gubb et al., 1984, Ashburner et al., 1990, Grau et al., 1984) stc (Cai et al., 2001, Ashburner et al., 1982, Ashburner, 1982, Gubb et al., 1984, Ashburner et al., 1990, Grau et al., 1984) TfIIS (Cai et al., 2001, Ashburner et al., 1990) vas (Ashburner et al., 1990, Cai et al., 2001) vig (Cai et al., 2001) wor (Cai et al., 2001, Ashburner et al., 1982, Ashburner, 1982, Gubb et al., 1984, Ashburner et al., 1990, Grau et al., 1984)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	Adh (Ashburner et al., 1982, Ashburner, 1982, Gubb et al., 1984, Grau et al., 1984) Ance (Gubb et al., 1984) Arpc1 (Gubb et al., 1984) b (Gubb et al., 1984) BicC (Ashburner et al., 1990) cact (Ashburner et al., 1990) Ca-α1D (Ashburner et al., 1990) chif (Ashburner et al., 1990) cni (Ashburner et al., 1990) crp (Ashburner et al., 1990) CycE (Ashburner et al., 1982, Ashburner, 1982, Gubb et al., 1984, Ashburner et al., 1990, Grau et al., 1984) Cyp303a1 (Ashburner et al., 1990) dac (Ashburner et al., 1990) DNApol-γ35 (Gubb et al., 1984) dyn-p25 (Ashburner, 1982, Gubb et al., 1984) elA (Ashburner et al., 1982, Gubb et al., 1984, Grau et al., 1984) elB (Grau et al., 1984) fzy (Ashburner et al., 1990) Gli (Ashburner et al., 1990) heix (Ashburner et al., 1990) kuz (Gubb et al., 1984) l(2)34Db (Gubb et al., 1984) l(2)34Fc (Gubb et al., 1984, Ashburner et al., 1982) l(2)34Fd (Gubb et al., 1984) l(2)35Bc (Ashburner, 1982, Gubb et al., 1984) l(2)35Bd (Ashburner, 1982, Gubb et al., 1984) l(2)35Be (Ashburner, 1982, Gubb et al., 1984) l(2)35Bg (Ashburner et al., 1982, Ashburner, 1982, Gubb et al., 1984) l(2)35De (Ashburner et al., 1990) l(2)35Df (Ashburner et al., 1990) l(2)35Di (Ashburner et al., 1990) l(2)36Aa (Ashburner et al., 1990) l(2)36Ab (Ashburner et al., 1990) l(2)36Ac (Ashburner et al., 1990) l(2)36Ad (Ashburner et al., 1990) mol (Ashburner et al., 1982, Ashburner, 1982, Gubb et al., 1984, Grau et al., 1984) mRpL4 (Ashburner et al., 1990) ms(2)35Eb (Ashburner et al., 1990) NimA (Gubb et al., 1984) NimC3 (Gubb et al., 1984) noc (Ashburner et al., 1982, Gubb et al., 1984, Grau et al., 1984) Orc5 (Gubb et al., 1984) osp (Ashburner et al., 1982, Gubb et al., 1984, Grau et al., 1984) pburs (Ashburner et al., 1982, Gubb et al., 1984, Grau et al., 1984) Pgant35A (Ashburner et al., 1982, Gubb et al., 1984) plo (Ashburner et al., 1990) rk (Gubb et al., 1984) RpII33 (Gubb et al., 1984) Sos (Gubb et al., 1984) Su(H) (Ashburner, 1982, Gubb et al., 1984, Ashburner et al., 1990, Grau et al., 1984) Syx5 (Ashburner et al., 1990) tam (Gubb et al., 1984) wb (Gubb et al., 1984) wek (Ashburner et al., 1990)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	Df(2L)TE35BC-3 embryos show defective neuroblast asymmetry. Neuroblast spindles are misoriented as compared to wild-type, occasionally they are completely reversed. (Cai et al., 2001) Chromosome has no effect on the physical interaction between tandemly duplicated copies of w⁺ and z¹, despite having breakpoints within the critical region. (Gubb et al., 1990) Homozygous embryos fail to form a ventral furrow. Cephalic furrow formation, invagination of the endoderm and germ band elongation do take place in these embryos. (Grau et al., 1984) Df(2L)64j/Df(2L)TE35BC-3 heterozygotes are deleted for ck only and are larval lethal. (Gubb et al., 1984)
Stocks ( 0 )

Notes on Origin
Discoverer	Gubb.

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments
	Aberration has no effect on z but has breakpoints within the z critical region. (Gubb et al., 1990)
Synonyms & Secondary IDs ( 6 )
Reported As
Symbol Synonym	Df(2L)TE35BC-3 (Siegrist and Doe, 2005) Df(2L)TE36 Df(2L)TE36(R)GW3 (Ashburner et al., 1990, Gubb et al., 1990, ) Df(2L)TE36-GC (Ashburner et al., 1983, Ashburner, 1982, Ashburner et al., 1982) Df(2L)TE36-GW3 (Grau et al., 1984) GW3 (Gubb et al., 1984)
Name Synonym
Secondary FlyBase IDs

References ( 14 )
Research paper	Siegrist and Doe, 2005, Cell 123(7): 1323--1335 Microtubule-induced Pins/G alpha i cortical polarity in Drosophila neuroblasts. [FBrf0189924] Sawamura et al., 2004, Genetics 166(2): 789--796 Genetic complexity underlying hybrid male sterility in Drosophila. [FBrf0174711] Cai et al., 2003, Cell 112(1): 51--62 Apical complex genes control mitotic spindle geometry and relative size of daughter cells in Drosophila neuroblast and pI asymmetric divisions. [FBrf0155600] Cai et al., 2001, EMBO J. 20(7): 1704--1714 A family of Snail-related zinc finger proteins regulates two distinct and parallel mechanisms that mediate Drosophila neuroblast asymmetric divisions. [FBrf0135740] Pasyukova et al., 2000, Genetics 156(3): 1129--1146 Deficiency mapping of quantitative trait loci affecting longevity in Drosophila melanogaster. [FBrf0131237] Ashburner et al., 1990, Genetics 126: 679--694 The genetics of a small autosomal region of Drosophila melanogaster containing the structural gene for alcohol dehydrogenase. [FBrf0051973] Gubb et al., 1990, Genetics 126: 167--176 A novel transvection phenomenon affecting the white gene of Drosophila melanogaster. [FBrf0051930] Grau et al., 1984, Genetics 108: 347--360 Mutation and chromosomal rearrangements affecting the expression of snail, a gene involved in embryonic patterning in Drosophila melanogaster. [FBrf0063478] Gubb et al., 1984, Chromosoma 91: 54--64 The genetic analysis of a large transposing element of Drosophila melanogaster. The insertion of a w⁺ rst⁺ TE into the ck locus. [FBrf0040529] Ashburner et al., 1983, Genetics 104: 405--431 The genetics of a small autosomal region of Drosophila melanogaster containing the structural gene for alcohol dehydrogenase. [FBrf0039455] Ashburner, 1982, Genetics 101: 447--459 The genetics of a small autosomal region of Drosophila melanogaster containing the structural gene for Alcohol dehydrogenase. [FBrf0038053] Ashburner et al., 1982, Genetics 102: 401--420 The genetics of a small chromosome region of Drosophila melanogaster containing the structural gene for Alcohol dehydrogenase. [FBrf0038047]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]
Book	Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster. The Genome of Drosophila melanogaster. [FBrf0066905]