FlyBase Aberration Report: Dmel\Df(2L)TW137

General Information

Symbol

Df(2L)TW137

Species

D. melanogaster

Name

Deficiency (2L) Ted Wright

FlyBase ID

FBab0001645

Feature type

chromosomal_deletion

Also Known As

Df(2L)137

Computed Breakpoints include

36C2-36C4;37B9-37B10

Features within 36C2--37B10

Sequence coordinates

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

Progenitor

Mutagen

X ray

(Stathakis et al., 1995, Wright et al., 1976)

Class of aberration (relative to wild type)

chromosomal_deletion

(FlyBase, 2007)

Class of aberration (relative to progenitor)

chromosomal_deletion

(Zak, 1998, Pauli et al., 1995, Pentz et al., 1990, Wright et al., 1976)

Breakpoints

36C2-36C4;37B9-37C1

(Zak, 1998, Pauli et al., 1995, Pentz et al., 1990, Wright et al., 1976)

Causes alleles

Carries alleles

Transposon Insertions

Formalized genetic data

l(2)36Bd << bk1 << l(2)36Ca << pre << bk2 << hk

Genetic mapping information

Comments

This deletion removes multiple ribosomal protein-coding genes (in addition to other genes).

(Marygold et al., 2007)

Distal DNA breakpoints given (Steward, McNally, and Schedl, 1984, Nature 311: 262-65)

Comments on Cytology

Limits of break 1 from polytene analysis (FBrf0028752) Left limit of break 2 from polytene analysis (FBrf0028752) Right limit of break 2 from non-inclusion of Catsup (FBrf0084402)

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

amos

(Wright et al., 1976)

BicD

(Steward and Nusslein-Volhard, 1986)

CadN

(Brumby et al., 2004, Steward and Nusslein-Volhard, 1986, Wright et al., 1976)

(Schupbach and Wieschaus, 1991, Schupbach and Wieschaus, 1989, Tearle and Nusslein-Volhard, 1987, Steward and Nusslein-Volhard, 1986)

kel

(Xue and Cooley, 1993, Schupbach and Wieschaus, 1991, Steward and Nusslein-Volhard, 1986)

kon

(Schnorrer et al., 2007)

l(2)36Ca

(Steward and Nusslein-Volhard, 1986)

l(2)37Ad

(Doerig, 1999.8.9, BDGP Project Members, 1994-1999)

l(2)00455b

(BDGP Project Members, 1994-1999)

l(2)k13805

(BDGP Project Members, 1994-1999)

msl-1

(Bevan et al., 1993)

ncm

(Coelho et al., 2005, Marygold, 2005.1.19)

ninaD

(Steward and Nusslein-Volhard, 1986)

pre

(Schupbach and Wieschaus, 1991, Schupbach and Wieschaus, 1989)

qua

(Schnorrer et al., 2002, Bloomington Drosophila Stock Center, 1998.9.22, Mahajan-Miklos and Cooley, 1994, Steward and Nusslein-Volhard, 1986)

rdo

(Steward and Nusslein-Volhard, 1986, Wright et al., 1976)

RpS26

(Marygold, 2005.1.19, Wright et al., 1976)

tup

(Zak, 1998)

Partially deleted / disrupted

Molecular Data

Completely deleted

mRpL13

(Marygold et al., 2007)

RpL30

(Marygold et al., 2007)

RpS26

(Marygold et al., 2007)

Partially deleted

Genes NOT Deleted / Disrupted

Complementation Data

Acn

(Stathakis et al., 1995)

amd

(Stathakis et al., 1995, Wright et al., 1976)

AsnRS

(Stathakis et al., 1995)

(Wright et al., 1976)

brat

(Stathakis et al., 1995, BDGP Project Members, 1994-1999)

bst

(Boquet et al., 2000)

Catsup

(Stathakis et al., 1995, BDGP Project Members, 1994-1999)

crc

(Wright et al., 1976)

cub

(Stathakis et al., 1995)

DCTN6-p27

(Stathakis et al., 1995)

Ddc

(Stathakis et al., 1995, BDGP Project Members, 1994-1999, Wright et al., 1976)

hook

(Stathakis et al., 1995)

l(2)36Aa

(Steward and Nusslein-Volhard, 1986)

l(2)36Ab

(Steward and Nusslein-Volhard, 1986)

l(2)36Ac

(Steward and Nusslein-Volhard, 1986)

l(2)36Ad

(Steward and Nusslein-Volhard, 1986)

l(2)36Ba

(Steward and Nusslein-Volhard, 1986)

l(2)36Bb

(Steward and Nusslein-Volhard, 1986)

l(2)36Bc

(Steward and Nusslein-Volhard, 1986)

l(2)36Bd

(Steward and Nusslein-Volhard, 1986)

l(2)37Bb

(Stathakis et al., 1995)

l(2)37Cb

(Stathakis et al., 1995)

l(2)37Cd

(Stathakis et al., 1995)

l(2)37Db

(BDGP Project Members, 1994-1999)

l(2)10206

(BDGP Project Members, 1994-1999)

Lim3

(Stathakis et al., 1995)

(Wright et al., 1976)

M(2)39F

(Wright et al., 1976)

Mhc

(Steward and Nusslein-Volhard, 1986)

mib2

(Stathakis et al., 1995)

nAChRα6

(Watson et al., 2010)

Phb1

(Stathakis et al., 1995)

plo

(Steward and Nusslein-Volhard, 1986)

Polr1D

(Stathakis et al., 1995)

(Wright et al., 1976)

RpL30

(BDGP Project Members, 1994-1999)

Rpn3

(Stathakis et al., 1995)

tyr1

(Pentz et al., 1990)

γTub37C

(Stathakis et al., 1995)

Molecular Data

Genes Duplicated

Complementation Data

Completely duplicated

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Affected Genes Inferred by Location (0)

If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
In these cases, there will be no "Export to Hitlist" button to the left.

Related Comments

Phenotypic Data

In combination with other aberrations

Df(2L)MN-I is semi-lethal in combination with Df(2L)TW137. Surviving males and females have reduced fertility.

(Levine et al., 2007)

Inferred to overlap with: Df(2L)H20.

(Marygold, 2005.1.19)

Lethal over Df(2L)E71.

(Wright et al., 1976)

NOT in combination with other aberrations

Flies heterozygous for the deletion show a Minute bristle phenotype.

(Marygold et al., 2007)

The Df(2L)TW137 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion).

(Mason et al., 2004)

Heterozygosity for Df(2L)TW137 results in 1.0% X chromosome nondisjunction and 0.0% fourth chromosome nondisjunction in In(1)FM7/X ; sv^spa-pol females.

(Harris et al., 2003)

Df(2L)TW137 in combination with a pair of introgressions from D.simulans spanning 30F1-31E7 to 35D7-36A14 Dsim\Int(2L)S and 21A1 to 22D1--23A2 Dsim\Int(2L)D produces fertile male flies. These flies are female sterile.

(Sawamura et al., 2000)

Does not cause unconditional lethality in hybrid females when heterozygous with D.simulans chromosome.

(Coyne et al., 1998)

No second site non-complementing phenotype with zip^Ebr and zip^mhc-c6.1.

(Halsell and Kiehart, 1998)

Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovo^D2.

(Pauli et al., 1995)

Moderate Minute.

(Wright et al., 1976)

Stocks (3)

Bloomington

420

Df(2L)TW137, cn¹ bw¹/CyO, Dp(2;2)M(2)m⁺

Kyoto

108900

Df(2L)TW137, cn¹ bw¹/CyO, Dp(2;2)M(2)m⁺

103254

CyO, Dp(2;2)M(2)m⁺ / Df(2L)TW137, cn¹ bw¹

Notes on Origin

Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms and Secondary IDs (6)

Reported As

Symbol Synonym

Df(2L)137

(Zak, 1998, Wright et al., 1976, Wright et al., 1976)

Df(2L)^TW137

(Muraoka et al., 2018)

Df(2L)TW137

(Clough et al., 2014, Schäfer et al., 2014, Fernandes and Rao, 2011, Watson et al., 2010, O'Farrell et al., 2008, Vicente-Crespo et al., 2008, Levine et al., 2007, Schnorrer et al., 2007)

Df-TW137

(Schnorrer et al., 2007)

TW137

(Yamaguchi et al., 1999)

Name Synonyms

Deficiency (2L) Ted Wright

Secondary FlyBase IDs

FBab0017886

References (55)

Report Sections

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