Aberration Dmel\Df(2L)TW2

General Information
Symbol	Dmel\Df(2L)TW2	Species	D. melanogaster
Name	Deficiency (2L) Ted Wright	FlyBase ID	FBab0001649
Feature type	chromosomal_deletion
Also Known As	Df(2L)2

Computed Breakpoints include	37D6-37E1;38E6-38E9
Deleted segment	37D6--38E9
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor	amos^Tft (Wright et al., 1976)
Mutagen	X ray (Stathakis et al., 1995)
Class of aberration (relative to progenitor)	chromosomal_deletion (Wright et al., 1976, Pauli et al., 1995)
Breakpoints	37D2-37E1;38E6-38E9 (Wright et al., 1976, Pauli et al., 1995)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	l(2)37Dg << bk1 << l(2)37Dm << del << bk2 << crc
Genetic mapping information
Comments
Comments on Cytology
	Left limit of break 1 from non-inclusion of l(2)37Dc (FBrf0028753) Right limit of break 1 from polytene analysis (FBrf0028752) Limits of break 2 from polytene analysis (FBrf0082455)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	Bl (Butler et al., 2001, Wright et al., 1976) cad (Butler et al., 2001) del (Schupbach and Wieschaus, 1991) dia (Butler et al., 2001) Fs(2)Ket (Schupbach and Wieschaus, 1991, Butler et al., 2001) fs(2)lto3 (Schupbach and Wieschaus, 1991) fs(2)ltoPP43 (Butler et al., 2001, Schupbach and Wieschaus, 1991) fs(2)ltoRV64 (Schupbach and Wieschaus, 1991) Hr38 (Butler et al., 2001) ik2 (Butler et al., 2001) l(2)37Di (Wright et al., 1976, Brittnacher and Ganetzky, 1983) l(2)37Dk (Wright et al., 1976) l(2)37Dl (Wright et al., 1976) l(2)37Dm (Wright et al., 1976) l(2)38EFb (Butler et al., 2001) l(2)01528 (Butler et al., 2001) pr (Butler et al., 2001, Wright et al., 1976) scw (Nusslein-Volhard et al., 1984) spi (BDGP Project Members, 1994-1999) spir (Schupbach and Wieschaus, 1991) swm (Wright et al., 1976, Brittnacher and Ganetzky, 1983, Gay and Contamine, 1993) vari (Butler et al., 2001) vls (Schupbach and Wieschaus, 1986, Tearle and Nusslein-Volhard, 1987, Schupbach and Wieschaus, 1989, Schupbach and Wieschaus, 1991)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	amd (Wright et al., 1976) amos (Wright et al., 1976) brat (Brittnacher and Ganetzky, 1983) CadN (Wright et al., 1976) crc (Wright et al., 1976) Ddc (Wright et al., 1976) esc (Wright et al., 1976) hk (Wright et al., 1976) l(2)37CDa (Wright et al., 1976) l(2)37CDb (Wright et al., 1976) l(2)37CDc (Wright et al., 1976) l(2)37CDd (Wright et al., 1976) l(2)37CDe (Wright et al., 1976) l(2)37CDf (Wright et al., 1976) l(2)37Db (Wright et al., 1976, Brittnacher and Ganetzky, 1983) l(2)37Dc (Wright et al., 1976, Brittnacher and Ganetzky, 1983) l(2)37De (Brittnacher and Ganetzky, 1983) l(2)38EFd (Butler et al., 2001) lt (Wright et al., 1976) M(2)39F (Wright et al., 1976) RanGAP (Brittnacher and Ganetzky, 1983) rdo (Wright et al., 1976) RpS26 (Wright et al., 1976)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovo^D2. (Pauli et al., 1995)
Stocks ( 3 )
Bloomington	3780 Df(2L)TW2, amos^Tft l(2)74i¹/CyO
Kyoto	107228 Df(2L)TW2, amos^Tft l(2)74i¹/CyO 101419 CyO, Dp(2;2)M(2)m⁺, Cy¹ dp^lv1 pr¹ cn² / Df(2L)TW2, amos^Tft l(2)74i¹
Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments
	The Df(2L)TW2 chromosome acts as a dominant weak suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion), but this is a false positive result (the suppressor is not within the bounds of the deficient region) because the region of the deficiency is covered by one or more nonsuppressing deficiencies. (Mason et al., 2004) Chromosome also carries amos^Tft and l(2)74i¹. (Wright et al., 1976) Complementation data suggest that l(2)37De² and l(2)37De³ complement Df(2L)TW2 whereas l(2)37De⁴ and l(2)37De⁵ fail to complement Df(2L)TW2. (Wright et al., 1976)
Synonyms & Secondary IDs ( 6 )
Reported As
Symbol Synonym	2 (Brittnacher and Ganetzky, 1983) Df(2)TW2 (Lehmann, 1988) Df(2L)2 (Wright et al., 1976, Wright et al., 1976, Nusslein-Volhard et al., 1984, ) Df(2L)TW2 (Crest et al., 2007, Kuranaga et al., 2006, Wu et al., 2007) Df(2R)TW2 (Wolfgang and Forte, 1995)
Name Synonym	Deficiency (2L) Ted Wright
Secondary FlyBase IDs

References ( 31 )

Generate a list of	All references relating to this aberration ( 31 )

List References by type	Research paper ( 26 ) Personal communication to FlyBase ( 1 ) Abstract ( 1 ) FlyBase analysis ( 1 ) Stock list ( 1 ) Book ( 1 )
Recent research papers (0)
	All research papers listed in FlyBase were published before 2011 Show research papers ...