FlyBase Aberration Report: Dmel\Df(2L)TW2

General Information

Symbol

Df(2L)TW2

Species

D. melanogaster

Name

Deficiency (2L) Ted Wright

FlyBase ID

FBab0001649

Feature type

chromosomal_deletion

Also Known As

Df(2L)2

Computed Breakpoints include

37D6-37E1;38E6-38E9

Features within 37D6--38E9

Sequence coordinates

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

Progenitor

amos^Tft

(Wright et al., 1976)

Mutagen

X ray

(Stathakis et al., 1995)

Class of aberration (relative to wild type)

chromosomal_deletion

(FlyBase, 2007)

Class of aberration (relative to progenitor)

chromosomal_deletion

(Pauli et al., 1995, Wright et al., 1976)

Breakpoints

37D2-37E1;38E6-38E9

(Pauli et al., 1995, Wright et al., 1976)

Causes alleles

Carries alleles

Transposon Insertions

Formalized genetic data

l(2)37Dg << bk1 << l(2)37Dm << del << bk2 << crc

Genetic mapping information

Comments

Comments on Cytology

Left limit of break 1 from non-inclusion of l(2)37Dc (FBrf0028753) Right limit of break 1 from polytene analysis (FBrf0028752) Limits of break 2 from polytene analysis (FBrf0082455)

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

(Butler et al., 2001, Wright et al., 1976)

cad

(Butler et al., 2001)

del

(Schupbach and Wieschaus, 1991)

dia

(Butler et al., 2001)

Fs(2)Ket

(Butler et al., 2001, Schupbach and Wieschaus, 1991)

fs(2)lto3

(Schupbach and Wieschaus, 1991)

fs(2)ltoPP43

(Butler et al., 2001, Schupbach and Wieschaus, 1991)

fs(2)ltoRV64

(Schupbach and Wieschaus, 1991)

Hr38

(Butler et al., 2001)

IKKε

(Butler et al., 2001)

l(2)37Di

(Brittnacher and Ganetzky, 1983, Wright et al., 1976)

l(2)37Dk

(Wright et al., 1976)

l(2)37Dl

(Wright et al., 1976)

l(2)37Dm

(Wright et al., 1976)

l(2)38EFb

(Butler et al., 2001)

l(2)01528

(Butler et al., 2001)

(Butler et al., 2001, Wright et al., 1976)

scw

(Nusslein-Volhard et al., 1984)

spi

(BDGP Project Members, 1994-1999)

spir

(Schupbach and Wieschaus, 1991)

swm

(Gay and Contamine, 1993, Brittnacher and Ganetzky, 1983, Wright et al., 1976)

vari

(Butler et al., 2001)

vls

(Schupbach and Wieschaus, 1991, Schupbach and Wieschaus, 1989, Tearle and Nusslein-Volhard, 1987, Schupbach and Wieschaus, 1986)

Partially deleted / disrupted

Molecular Data

Completely deleted

Partially deleted

Genes NOT Deleted / Disrupted

Complementation Data

amd

(Wright et al., 1976)

amos

(Wright et al., 1976)

brat

(Brittnacher and Ganetzky, 1983)

CadN

(Wright et al., 1976)

crc

(Wright et al., 1976)

Ddc

(Wright et al., 1976)

esc

(Wright et al., 1976)

hook

(Wright et al., 1976)

l(2)37CDa

(Wright et al., 1976)

l(2)37CDb

(Wright et al., 1976)

l(2)37CDc

(Wright et al., 1976)

l(2)37CDd

(Wright et al., 1976)

l(2)37CDe

(Wright et al., 1976)

l(2)37CDf

(Wright et al., 1976)

l(2)37Db

(Brittnacher and Ganetzky, 1983, Wright et al., 1976)

l(2)37Dc

(Brittnacher and Ganetzky, 1983, Wright et al., 1976)

l(2)37De

(Brittnacher and Ganetzky, 1983)

l(2)38EFd

(Butler et al., 2001)

(Wright et al., 1976)

M(2)39F

(Wright et al., 1976)

RanGAP

(Brittnacher and Ganetzky, 1983)

rdo

(Wright et al., 1976)

RpS26

(Wright et al., 1976)

Molecular Data

Genes Duplicated

Complementation Data

Completely duplicated

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Affected Genes Inferred by Location (0)

If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
In these cases, there will be no "Export to Hitlist" button to the left.

Related Comments

Phenotypic Data

In combination with other aberrations

NOT in combination with other aberrations

Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovo^D2.

(Pauli et al., 1995)

Stocks (3)

Bloomington

3780

Df(2L)TW2, amos^Tft l(2)74i¹/CyO

Kyoto

107228

Df(2L)TW2, amos^Tft l(2)74i¹/CyO

101419

CyO, Dp(2;2)M(2)m⁺, Duox^Cy dpy^lv1 pr¹ cn² / Df(2L)TW2, amos^Tft l(2)74i¹

Notes on Origin

Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

The Df(2L)TW2 chromosome acts as a dominant weak suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion), but this is a false positive result (the suppressor is not within the bounds of the deficient region) because the region of the deficiency is covered by one or more nonsuppressing deficiencies.

(Mason et al., 2004)

Chromosome also carries amos^Tft and l(2)74i¹.

(Wright et al., 1976)

Complementation data suggest that l(2)37De² and l(2)37De³ complement Df(2L)TW2 whereas l(2)37De⁴ and l(2)37De⁵ fail to complement Df(2L)TW2.

(Wright et al., 1976)

Synonyms and Secondary IDs (6)

Reported As

Symbol Synonym

(Brittnacher and Ganetzky, 1983)

Df(2)TW2

(Lehmann, 1988)

Df(2L)2

(Nusslein-Volhard et al., 1984, Wright et al., 1976, Wright et al., 1976)

Df(2L)TW2

(Crest et al., 2007, Wu et al., 2007, Kuranaga et al., 2006)

Df(2R)TW2

(Wolfgang and Forte, 1995)

Name Synonyms

Deficiency (2L) Ted Wright

Secondary FlyBase IDs

References (31)

Report Sections

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