A Database of Drosophila Genes & Genomes

FB2013_03, released May 7th, 2013
 

Aberration Dmel\Df(2L)TW84

General Information
SymbolDmel\Df(2L)TW84SpeciesD. melanogaster
NameDeficiency (2L) Ted WrightFlyBase IDFBab0001658
Feature typechromosomal_deletion
Also Known AsDf(2L)84
Computed Breakpoints include 38A1;39D3-39E1
Deleted segment38A1--39E1
Map ( GBrowse ) GBrowse View Help Untitled Document

Error

No matching regions found.

Sequence coordinates
2L:19,691,198..19,701,223 [+] (Df(2L)TW84:bk1)
(Krueger et al., 1996)
Member of large scale dataset(s)
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Description
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FB2013_03
FB2013_02
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hide Nature of the Aberration
Cytological Order
Progenitor
amosTft
(Wright et al., 1976)
Mutagen
X ray
(Stathakis et al., 1995, Siegel, 1981)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Wright et al., 1976, Kania et al., 1995, Pauli et al., 1995, Duffy et al., 1996, Fitzpatrick et al., 1995, Harbecke and Lengyel, 1995)
Breakpoints
37F5-38A1;38B2-38C1
(Kania et al., 1995)
37F5-38A1;39D3-39E1
(Wright et al., 1976, Pauli et al., 1995, Harbecke and Lengyel, 1995, Fitzpatrick et al., 1995, Duffy et al., 1996)
Causes alleles
LarTW84
(Krueger et al., 1996)
Carries alleles
Transposon Insertions
Formalized genetic data Lar << bk1 << l(2)37Fd << l(2)39ADc << bk2 << Low
Genetic mapping information
Comments
Breakpoint(s) molecularly mapped
(Rutledge et al., 1992)
hide Comments on Cytology
Ref: Lindsley and Zimm, 1992
(Kania et al., 1995)
Left limit of break 1 from non-inclusion of Lar (FBrf0086508) Right limit of break 1 from inclusion of Lar (FBrf0083926) Limits of break 2 from polytene analysis (FBrf0028752)
 
hide Sequence Crossreferences
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
hide Gene Deletion & Duplication Data
hide Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Acon
(BDGP Project Members, 1994-1999)
barr
(Liu et al., 1999, Spradling et al., 1999, BDGP Project Members, 1994-1999, Kania et al., 1995)
Bl
(Wright et al., 1976, Siegel, 1981)
bur
(Neufeld et al., 1998, BDGP Project Members, 1994-1999)
bwa
(Boquet et al., 2000)
cad
(Harbecke and Lengyel, 1995)
crc
(Wright et al., 1976, Sparrow, 1981, Siegel, 1981)
dia
(Butler et al., 2001, Giansanti et al., 2004, Castrillon et al., 1993, BDGP Project Members, 1994-1999, Castrillon and Wasserman, 1994)
fs(2)ltoPP43
(Butler et al., 2001)
Gr39a
(Spradling et al., 1999, BDGP Project Members, 1994-1999)
l(2)37Fe
(Butler et al., 2001)
l(2)39Aa
(Siegel, 1981)
l(2)39Ad
(Siegel, 1981)
l(2)39ADa
(Siegel, 1981)
l(2)39ADb
(Siegel, 1981)
l(2)39ADc
(Siegel, 1981)
l(2)39ADd
(Siegel, 1981)
l(2)39ADe
(Siegel, 1981)
l(2)39Ah
(Siegel, 1981)
l(2)39DEa
(Siegel, 1981)
l(2)39DEb
(Siegel, 1981)
l(2)39DEc
(Siegel, 1981)
l(2)39DEd
(Siegel, 1981)
l(2)39DEe
(Siegel, 1981)
l(2)39DEi
(Siegel, 1981)
l(2)39DEj
(Siegel, 1981)
l(2)39DEk
(Siegel, 1981)
l(2)k07215
(Spradling et al., 1999, BDGP Project Members, 1994-1999)
l(2)k07312b
(BDGP Project Members, 1994-1999)
Lar
(Fitzpatrick et al., 1995, Krueger et al., 1996)
Mpp6
(BDGP Project Members, 1994-1999)
neb
(BDGP Project Members, 1994-1999, Ohkura et al., 1997)
pr
(Butler et al., 2001, Wright et al., 1976, Siegel, 1981)
scw
(Nusslein-Volhard et al., 1984)
Su(dpp)39CDE
(Murthy, 1999.3.3)
vari
(Beitel and Krasnow, 2000)
vls
(Schupbach and Wieschaus, 1986, Tearle and Nusslein-Volhard, 1987)
Partially deleted / disrupted
l(2)39DEf
(Siegel, 1981)
l(2)39DEg
(Siegel, 1981)
l(2)39DEh
(Siegel, 1981)
l(2)39DEl
(Siegel, 1981)
l(2)39DEm
(Siegel, 1981)
l(2)39DEn
(Siegel, 1981)
l(2)39DEo
(Siegel, 1981)
Molecular Data
hide Genes NOT Deleted / Disrupted
Complementation Data
Acon
(Spradling et al., 1999)
amd
(Wright et al., 1976)
amos
(Wright et al., 1976)
CadN
(Wright et al., 1976)
Ddc
(Wright et al., 1976)
esc
(Wright et al., 1976)
hk
(Wright et al., 1976)
l(2)37Fc
(Butler et al., 2001)
l(2)39Ea
(Beaton, 1998.3.3)
l(2)01528
(Spradling et al., 1999, BDGP Project Members, 1994-1999)
l(2)k07713
(BDGP Project Members, 1994-1999)
l(2)k11241
(BDGP Project Members, 1994-1999)
Low
(Bhadra et al., 1997)
lt
(Wright et al., 1976, Siegel, 1981)
M(2)39F
(Wright et al., 1976, Siegel, 1981)
rdo
(Wright et al., 1976)
RpS26
(Wright et al., 1976)
spi
(Spradling et al., 1999, BDGP Project Members, 1994-1999)
Molecular Data
hide Genes Duplicated
Complementation Data
Molecular Data
hide Genes NOT Duplicated
Complementation Data
Molecular Data
hide Related Comments
Partially complements l(2)39DEfI4, l(2)39DEhD95, l(2)39DElK234, l(2)39DEmK236, l(2)39DEnL110, l(2)39DEoL138 and l(2)39DEgK213.
(Siegel, 1981)
hide Phenotypic Data
In combination with other aberrations
Does not suppress the ry position effect variegation phenotype associated with In(3R)ryps11136.
(Rushlow et al., 1984)
NOT in combination with other aberrations
Heterozygosity for Df(2L)TW84 results in 3.3% X chromosome nondisjunction and 0.4% fourth chromosome nondisjunction in In(1)FM7/X ; svspa-pol females.
(Harris et al., 2003)
Heterozygotes show no adult central brain defect.
(Boquet et al., 2000)
Shows dominant enhancement of dominant haltere phenotype caused by Ubx195 and Ubx9.22.
(Burnette et al., 1999)
Does not cause unconditional lethality in hybrid females when heterozygous with D.simulans chromosome.
(Coyne et al., 1998)
No second site non-complementing phenotype with zipEbr and zipmhc-c6.1.
(Halsell and Kiehart, 1998)
Shows no maternal enhancement of dpphr4.
(Nicholls and Gelbart, 1998)
Dominantly causes tergite defects in less than 50% of run3 heterozygotes.
(Duffy et al., 1996)
Deficient embryos show an uninterpretable mutant midgut phenotype.
(Bilder and Scott, 1995)
Homozygous embryos are very abnormal compared to wild-type.
(Harbecke and Lengyel, 1995)
Heterozygosity for this deletion suppresses the mutant ovarian phenotype of ovoD2.
(Pauli et al., 1995)
hide Stocks ( 2 )
Bloomington
3346
Df(2L)TW84, l(2)74i1, amosTft LarTW84/CyO
Kyoto
106994
Df(2L)TW84, l(2)74i1, amosTft LarTW84/CyO
hide Notes on Origin
Discoverer
hide Balancer / Genotype Variants of the Aberration
hide Separable Components
hide Other Comments
The Df(2L)TW84 chromosome may act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion), but the eye colour phenotype in the presence of Df(2L)TW84 overlaps the eye colour phenotype in a wild-type background so it cannot be unequivocally demonstrated that the deficiency chromosome uncovers a suppressor of telomeric silencing. In addition, any suppression is a false positive result (the suppressor is not within the bounds of the deficient region) because the region of the deficiency is covered by one or more nonsuppressing deficiencies.
(Mason et al., 2004)
Chromosome also carries amosTft and l(2)74i1.
(Wright et al., 1976)
hide Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym
Df(2L)84
(Sparrow, 1981, Rushlow et al., 1984, Siegel, 1981, Wright et al., 1976, Takano and McKee, 1995, Nusslein-Volhard et al., 1984, )
Df(2L)TW84
(Crest et al., 2007)
TW84
(Beaton, 1998.3.3)
Name Synonym
Deficiency (2L) Ted Wright
 
Secondary FlyBase IDs
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