Aberration Dmel\Df(2L)VA12

General Information
Symbol	Dmel\Df(2L)VA12	Species	D. melanogaster
Name		FlyBase ID	FBab0001665
Feature type	chromosomal_deletion
Also Known As	VA12

Computed Breakpoints include	37C2-37C5;38B5-38C1
Deleted segment	37C2--38C1
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Aberration
Cytological Order
Progenitor
Mutagen	gamma ray (Wright et al., 1981, Stathakis et al., 1995)
Class of aberration (relative to progenitor)	chromosomal_deletion (Dura et al., 1993, Gilbert et al., 1984, Wright et al., 1981, Pauli et al., 1995, Stathakis et al., 1995, Fitzpatrick et al., 1995, Whalen and Wilson, 1986)
Breakpoints	37C1-37C5;38B1-38C2 (Gilbert et al., 1984, Whalen and Wilson, 1986) 37C1-37D1;38B1-38C2 (Wright et al., 1981) 37C2-37C5;38B2-38C1 (Dura et al., 1993, Pauli et al., 1995, Fitzpatrick et al., 1995, Stathakis et al., 1995)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	l(2)37Cg << bk1 << brat << l(2)38Aa << bk2 << ms(2)38C
Genetic mapping information
Comments	Breakpoint(s) molecularly mapped (Gilbert et al., 1984, Hirsh and Davidson, 1981) Ddc DNA coordinates from Gilbert, Hirsh and Wright, 1984, Genetics 106: 679-84: Distal breakpoint between +25.5 and +28.1 kb
Comments on Cytology
	Left limit of break 1 from polytene analysis (FBrf0080317) Right limit of break 1 from polytene analysis (FBrf0040975) Left limit of break 2 from inclusion of l(2)38Aa (citation unavailable) Right limit of break 2 from polytene analysis (FBrf0080317)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	barr (Butler et al., 2001, BDGP Project Members, 1994-1999) brat (Wright et al., 1981, Gilbert et al., 1984, Pentz et al., 1986, BDGP Project Members, 1994-1999, Stathakis et al., 1995, Wright, 1996) l(2)37Fe (Butler et al., 2001) l(2)38Ab (Butler et al., 2001) Lar (Fitzpatrick et al., 1995) neb (Butler et al., 2001, BDGP Project Members, 1994-1999) pigeon (Dura et al., 1993) pr (Butler et al., 2001, Wright et al., 1981) spi (Tio et al., 1994) γTub37C (Stathakis et al., 1995, Wright, 1996)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	Aats-asn (Wright et al., 1981, Pentz et al., 1986, Stathakis et al., 1995, Wright, 1996) Acn (Wright, 1996, Stathakis et al., 1995, Gilbert et al., 1984, Pentz et al., 1986, Wright et al., 1981) AcpC (Whalen and Wilson, 1986) amd (Wright et al., 1981, Gilbert et al., 1984, Stathakis et al., 1995, Wright, 1996) Bl (Butler et al., 2001) cad (Butler et al., 2001) Catsup (Wright et al., 1981, Gilbert et al., 1984, Pentz et al., 1986, Stathakis et al., 1995, Wright, 1996) cub (Gilbert et al., 1984, Pentz et al., 1986, Stathakis et al., 1995, Wright, 1996) Ddc (Wright et al., 1981, Gilbert et al., 1984, Stathakis et al., 1995, Wright, 1996) hk (Wright et al., 1981, Gilbert et al., 1984, Pentz et al., 1986, Stathakis et al., 1995, Wright, 1996) l(2)37Bb (Wright et al., 1981, Gilbert et al., 1984, Pentz et al., 1986, Stathakis et al., 1995, Wright, 1996) l(2)37Cb (Wright et al., 1981, Pentz et al., 1986, Stathakis et al., 1995, Wright, 1996) l(2)37Cc (Wright et al., 1981, Pentz et al., 1986, Stathakis et al., 1995, Wright, 1996) l(2)37Cd (Wright et al., 1981, Pentz et al., 1986, Stathakis et al., 1995, Wright, 1996) l(2)37Ce (Wright et al., 1981, Pentz et al., 1986, Stathakis et al., 1995, Wright, 1996) l(2)37Cg (Pentz et al., 1986, Stathakis et al., 1995, Wright, 1996) l(2)38Db (Butler et al., 2001) l(2)k09314b (BDGP Project Members, 1994-1999) Lim3 (Wright et al., 1981, Gilbert et al., 1984, Pentz et al., 1986, Stathakis et al., 1995, Wright, 1996) mib2 (Gilbert et al., 1984, Pentz et al., 1986, Stathakis et al., 1995, Wright, 1996) Rpn3 (Stathakis et al., 1995, Gilbert et al., 1984, Pentz et al., 1986, Wright, 1996) spir (Butler et al., 2001)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	Mutation does not affect the level of w expression in ph-p^lac+3 flies. (Fauvarque et al., 1995) Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovo^D2. (Pauli et al., 1995)
Stocks ( 2 )
Bloomington	3171 Df(2L)VA12, cn¹ bw¹/CyO
Kyoto	106892 Df(2L)VA12, cn¹ bw¹/CyO
Notes on Origin
Discoverer	A. Tomsett.

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments
	The Df(2L)VA12 chromosome acts as a dominant moderate suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion), but this is a false positive result (the suppressor is not within the bounds of the deficient region) because the region of the deficiency is covered by one or more nonsuppressing deficiencies. (Mason et al., 2004) 37C2-37C5 breakpoint is between position +26.5 and +29.1 on the Ddc map relative to the HpaI restriction site near the 3' end of Ddc. (Stathakis et al., 1995)
Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	Df(2L)VA12 (Casso et al., 2008) Df(2L)VA¹² (Tully et al., 1992) VA12 (Yamaguchi et al., 2001, Yamaguchi et al., 1999, Hirose et al., 2001)
Name Synonym
Secondary FlyBase IDs

References ( 30 )

Generate a list of	All references relating to this aberration ( 30 )

List References by type	Research paper ( 26 ) Personal communication to FlyBase ( 1 ) Abstract ( 1 ) FlyBase analysis ( 1 ) Book ( 1 )
Recent research papers (0)
	All research papers listed in FlyBase were published before 2011 Show research papers ...